| Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex M Grenon, C Gilbert, NF Lowndes Nature cell biology 3 (9), 844-847, 2001 | 262 | 2001 |
| Eukaryotic DNA damage checkpoint activation in response to double-strand breaks K Finn, NF Lowndes, M Grenon Cellular and Molecular Life Sciences 69, 1447-1473, 2012 | 186 | 2012 |
| 53BP1: function and mechanisms of focal recruitment JE FitzGerald, M Grenon, NF Lowndes Biochemical Society Transactions 37 (4), 897-904, 2009 | 183 | 2009 |
| Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation GWL Toh, AM O'Shaughnessy, S Jimeno, IM Dobbie, M Grenon, S Maffini, ... DNA repair 5 (6), 693-703, 2006 | 162 | 2006 |
| MRN and the race to the break A Rupnik, NF Lowndes, M Grenon Chromosoma 119, 115-135, 2010 | 154 | 2010 |
| Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain M Grenon, T Costelloe, S Jimeno, A O'Shaughnessy, J FitzGerald, ... Yeast 24 (2), 105-119, 2007 | 146 | 2007 |
| Transcriptional Response of Candida parapsilosis following Exposure to Farnesol T Rossignol, ME Logue, K Reynolds, M Grenon, NF Lowndes, G Butler Antimicrobial agents and chemotherapy 51 (7), 2304-2312, 2007 | 97 | 2007 |
| Topoisomerase III acts upstream of Rad53p in the S-phase DNA damage checkpoint RK Chakraverty, JM Kearsey, TJ Oakley, M Grenon, MA de la Torre Ruiz, ... Molecular and Cellular Biology 21 (21), 7150-7162, 2001 | 88 | 2001 |
| Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle–regulated by CDK1 activity M Granata, F Lazzaro, D Novarina, D Panigada, F Puddu, CM Abreu, ... PLoS genetics 6 (8), e1001047, 2010 | 86 | 2010 |
| The MRN complex A Rupnik, M Grenon, N Lowndes Current Biology 18 (11), R455-R457, 2008 | 66 | 2008 |
| p56chk1 protein kinase is required for the DNA replication checkpoint at 37 C in fission yeast S Francesconi, M Grenon, D Bouvier, G Baldacci The EMBO Journal, 1997 | 59 | 1997 |
| Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor J FitzGerald, S Moureau, P Drogaris, E O'Connell, N Abshiru, A Verreault, ... PloS one 6 (2), e14714, 2011 | 52 | 2011 |
| Site-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1 CM Abreu, R Kumar, D Hamilton, AW Dawdy, K Creavin, S Eivers, K Finn, ... PLoS genetics 9 (4), e1003310, 2013 | 46 | 2013 |
| The budding yeast Rad9 checkpoint complex: chaperone proteins are required for its function CS Gilbert, M van den Bosch, CM Green, JE Vialard, M Grenon, ... EMBO reports 4 (10), 953-958, 2003 | 41 | 2003 |
| ING3 is required for ATM signaling and DNA repair in response to DNA double strand breaks A Mouche, J Archambeau, C Ricordel, L Chaillot, N Bigot, T Guillaudeux, ... Cell Death & Differentiation 26 (11), 2344-2357, 2019 | 30 | 2019 |
| Double-strand breaks trigger MRX-and Mec1-dependent, but Tel1-independent, checkpoint activation M Grenon, CP Magill, NF Lowndes, SP Jackson FEMS yeast research 6 (5), 836-847, 2006 | 30 | 2006 |
| PCNA and DNA Polymerase δ Catalytic Subunit fromSchizosaccharomyces pombeDo Not Interact Directly I Tratner, K Piard, M Grenon, M Perderiset, G Baldacci Biochemical and biophysical research communications 231 (2), 321-328, 1997 | 23 | 1997 |
| Researchers: share your passion for science! C Concannon, M Grenon Biochemical Society Transactions 44 (5), 1507-1515, 2016 | 22 | 2016 |
| Multiple approaches to study S. cerevisiae Rad9, a prototypical checkpoint protein AM O'Shaughnessy, M Grenon, C Gilbert, GWL Toh, CM Green, ... Methods in enzymology 409, 131-150, 2006 | 19 | 2006 |
| Fission yeast chk1 mutants show distinct responses to different types of DNA damaging treatments S Francesconi, M Smeets, M Grenon, J Tillit, J Blaisonneau, G Baldacci Genes to Cells 7 (7), 663-673, 2002 | 15 | 2002 |
Noel LowndesEstablished Professor of Biochemistry & Director, Centre for Chromsome BiologyVerified email at universityofgalway.ie