Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock Y Zhang, B Fang, MJ Emmett, M Damle, Z Sun, D Feng, SM Armour, ... Science 348 (6242), 1488-1492, 2015 | 340 | 2015 |
Tumor-associated B-cells induce tumor heterogeneity and therapy resistance R Somasundaram, G Zhang, M Fukunaga-Kalabis, M Perego, C Krepler, ... Nature communications 8 (1), 607, 2017 | 137 | 2017 |
Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion S Hong, W Zhou, B Fang, W Lu, E Loro, M Damle, G Ding, J Jager, ... Nature medicine 23 (2), 223-234, 2017 | 104 | 2017 |
Physiological suppression of lipotoxic liver damage by complementary actions of HDAC3 and SCAP/SREBP R Papazyan, Z Sun, YH Kim, PM Titchenell, DA Hill, W Lu, M Damle, ... Cell metabolism 24 (6), 863-874, 2016 | 80 | 2016 |
The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γ Y Zhang, R Papazyan, M Damle, B Fang, J Jager, D Feng, LC Peed, ... Genes & Development 31 (12), 1202-1211, 2017 | 74 | 2017 |
An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides SM Armour, JR Remsberg, M Damle, S Sidoli, WY Ho, Z Li, BA Garcia, ... Nature communications 8 (1), 1-11, 2017 | 69 | 2017 |
HNF6 and Rev-erbα integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanisms Y Zhang, B Fang, M Damle, D Guan, Z Li, YH Kim, M Gannon, MA Lazar Genes & development 30 (14), 1636-1644, 2016 | 65 | 2016 |
Deletion of histone deacetylase 3 in adult beta cells improves glucose tolerance via increased insulin secretion JR Remsberg, BN Ediger, WY Ho, M Damle, Z Li, C Teng, C Lanzillotta, ... Molecular metabolism 6 (1), 30-37, 2017 | 60 | 2017 |
Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice RE Soccio, Z Li, ER Chen, YH Foong, KK Benson, JR Dispirito, ... The Journal of clinical investigation 127 (4), 1451-1462, 2017 | 52 | 2017 |
Identification of C2CD4A as a human diabetes susceptibility gene with a role in β cell insulin secretion T Kuo, MJ Kraakman, M Damle, R Gill, MA Lazar, D Accili Proceedings of the National Academy of Sciences 116 (40), 20033-20042, 2019 | 42 | 2019 |
Genetic backgrounds determine brown remodeling of white fat in rodents G Ferrannini, M Namwanje, B Fang, M Damle, D Li, Q Liu, MA Lazar, ... Molecular metabolism 5 (10), 948-958, 2016 | 40 | 2016 |
Induction of α cell–restricted Gc in dedifferentiating β cells contributes to stress-induced β cell dysfunction T Kuo, M Damle, BJ González, D Egli, MA Lazar, D Accili JCI insight 4 (13), 2019 | 34 | 2019 |
A Polycomb domain found in committed cells impairs differentiation when introduced into PRC1 in pluripotent cells ES Jaensch, J Zhu, JC Cochrane, SK Marr, TA Oei, M Damle, ... Molecular cell 81 (22), 4677-4691. e8, 2021 | 28 | 2021 |
Elongin A associates with actively transcribed genes and modulates enhancer RNA levels with limited impact on transcription elongation rate in vivo MB Ardehali, M Damle, C Perea-Resa, MD Blower, RE Kingston Journal of Biological Chemistry 296, 2021 | 23 | 2021 |
Full methylation of H3K27 by PRC2 is dispensable for initial embryoid body formation but required to maintain differentiated cell identity SA Miller, M Damle, J Kim, RE Kingston Development 148 (7), dev196329, 2021 | 17 | 2021 |
S-phase enriched non-coding RNAs regulate gene expression and cell cycle progression O Yildirim, EC Izgu, M Damle, V Chalei, F Ji, RI Sadreyev, JW Szostak, ... Cell reports 31 (6), 2020 | 17 | 2020 |
Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle Y Gong, R Cao, G Ding, S Hong, W Zhou, W Lu, M Damle, B Fang, ... Molecular and cellular endocrinology 471, 22-32, 2018 | 14 | 2018 |
TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways IA Tchasovnikarova, SK Marr, M Damle, RE Kingston Molecular cell 82 (2), 479-491. e7, 2022 | 13 | 2022 |
HERVH-derived lncRNAs negatively regulate chromatin targeting and remodeling mediated by CHD7 FK Hsieh, F Ji, M Damle, RI Sadreyev, RE Kingston Life Science Alliance 5 (1), 2022 | 5 | 2022 |
H3K27me3 is dispensable for early differentiation but required to maintain differentiated cell identity SA Miller, M Damle, RE Kingston bioRxiv, 2020.06. 27.175612, 2020 | 2 | 2020 |