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Achim Werner
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Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease
DB Beck, MA Ferrada, KA Sikora, AK Ombrello, JC Collins, W Pei, ...
New England Journal of Medicine 383 (27), 2628-2638, 2020
9192020
Assembly and function of heterotypic ubiquitin chains in cell-cycle and protein quality control
RG Yau, K Doerner, ER Castellanos, DL Haakonsen, A Werner, N Wang, ...
Cell 171 (4), 918-933. e20, 2017
3232017
Cell-fate determination by ubiquitin-dependent regulation of translation
A Werner, S Iwasaki, CA McGourty, S Medina-Ruiz, N Teerikorpi, ...
Nature 525 (7570), 523-527, 2015
1912015
Novel somatic mutations in UBA1 as a cause of VEXAS syndrome
JA Poulter, JC Collins, C Cargo, RM De Tute, P Evans, D Ospina Cardona, ...
Blood, The Journal of the American Society of Hematology 137 (26), 3676-3681, 2021
1842021
Regulation of the CUL3 ubiquitin ligase by a calcium-dependent co-adaptor
CA McGourty, D Akopian, C Walsh, A Gorur, A Werner, R Schekman, ...
Cell 167 (2), 525-538. e14, 2016
1352016
Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis
MA Ferrada, S Savic, DO Cardona, JC Collins, H Alessi, ...
Blood, The Journal of the American Society of Hematology 140 (13), 1496-1506, 2022
1092022
Dimerization quality control ensures neuronal development and survival
EL Mena, RAS Kjolby, RA Saxton, A Werner, BG Lew, JM Boyle, ...
Science 362 (6411), eaap8236, 2018
822018
Disorders of ubiquitylation: unchained inflammation
DB Beck, A Werner, DL Kastner, I Aksentijevich
Nature Reviews Rheumatology 18 (8), 435-447, 2022
772022
Endosomal fusion upon SNARE knockdown is maintained by residual SNARE activity and enhanced docking
I Bethani, A Werner, C Kadian, U Geumann, R Jahn, SO Rizzoli
Traffic 10 (10), 1543-1559, 2009
592009
The Colossus of ubiquitylation: decrypting a cellular code
A Williamson, A Werner, M Rape
Molecular cell 49 (4), 591-600, 2013
562013
Ubiquitin-dependent regulation of stem cell biology
A Werner, AG Manford, M Rape
Trends in cell biology 27 (8), 568-579, 2017
492017
SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression
A Werner, A Disanza, N Reifenberger, G Habeck, J Becker, M Calabrese, ...
Nature cell biology 15 (2), 179-188, 2013
462013
Deubiquitylases in developmental ubiquitin signaling and congenital diseases
MA Basar, DB Beck, A Werner
Cell Death & Differentiation 28 (2), 538-556, 2021
392021
Linkage-specific deubiquitylation by OTUD5 defines an embryonic pathway intolerant to genomic variation
DB Beck, MA Basar, AJ Asmar, JJ Thompson, H Oda, DT Uehara, K Saida, ...
Science advances 7 (4), eabe2116, 2021
322021
Novel Somatic UBA1 Variant in a Patient With VEXAS Syndrome
B Stiburkova, K Pavelcova, M Belickova, SJ Magaziner, JC Collins, ...
Arthritis & Rheumatology 75 (7), 1285-1290, 2023
312023
Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions
A Werner, R Baur, N Teerikorpi, DU Kaya, M Rape
Elife 7, e35407, 2018
272018
Novel CUL3 Variant Causing Familial Hyperkalemic Hypertension Impairs Regulation and Function of Ubiquitin Ligase Activity
HE Chatrathi, JC Collins, LA Wolfe, TC Markello, DR Adams, WA Gahl, ...
Hypertension 79 (1), 60-75, 2022
222022
Myelodysplasia and bone marrow manifestations of somatic UBA1 mutated autoinflammatory disease
IE Obiorah, DB Beck, W Wang, A Ombrello, MA Ferrada, Z Wu, KA Sikora, ...
Blood 136, 20-21, 2020
222020
Nix interacts with WIPI2 to induce mitophagy
EN Bunker, F Le Guerroué, C Wang, MP Strub, A Werner, N Tjandra, ...
The EMBO journal 42 (22), e113491, 2023
212023
TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1
F Le Guerroué, EN Bunker, WM Rosencrans, JT Nguyen, MA Basar, ...
Molecular cell 83 (6), 927-941. e8, 2023
192023
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