| Towards a proteome-scale map of the human protein–protein interaction network JF Rual, K Venkatesan, T Hao, T Hirozane-Kishikawa, A Dricot, N Li, ... Nature 437 (7062), 1173-1178, 2005 | 3591 | 2005 |
| WAF1/CIP1 Is Induced in p53-mediated G1 Arrest and Apoptosis WS El-Deiry, JW Harper, PM O'Connor, VE Velculescu, CE Canman, ... Cancer research 54 (5), 1169-1174, 1994 | 3026 | 1994 |
| A mitochondrial protein compendium elucidates complex I disease biology DJ Pagliarini, SE Calvo, B Chang, SA Sheth, SB Vafai, SE Ong, ... Cell 134 (1), 112-123, 2008 | 2315 | 2008 |
| A map of the interactome network of the metazoan C. elegans S Li, CM Armstrong, N Bertin, H Ge, S Milstein, M Boxem, PO Vidalain, ... Science 303 (5657), 540-543, 2004 | 2206 | 2004 |
| Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial MN Ramasamy, AM Minassian, KJ Ewer, AL Flaxman, PM Folegatti, ... The Lancet 396 (10267), 1979-1993, 2020 | 1798 | 2020 |
| COT drives resistance to RAF inhibition through MAP kinase pathway reactivation CM Johannessen, JS Boehm, SY Kim, SR Thomas, L Wardwell, ... Nature 468 (7326), 968-972, 2010 | 1763 | 2010 |
| High-quality binary protein interaction map of the yeast interactome network H Yu, P Braun, MA Yıldırım, I Lemmens, K Venkatesan, J Sahalie, ... Science 322 (5898), 104-110, 2008 | 1746 | 2008 |
| A proteome-scale map of the human interactome network T Rolland, M Taşan, B Charloteaux, SJ Pevzner, Q Zhong, N Sahni, S Yi, ... Cell 159 (5), 1212-1226, 2014 | 1518 | 2014 |
| Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library JF Rual, J Ceron, J Koreth, T Hao, AS Nicot, T Hirozane-Kishikawa, ... Genome research 14 (10b), 2162-2168, 2004 | 1120 | 2004 |
| A reference map of the human binary protein interactome K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ... Nature 580 (7803), 402-408, 2020 | 1098 | 2020 |
| An empirical framework for binary interactome mapping K Venkatesan, JF Rual, A Vazquez, U Stelzl, I Lemmens, ... Nature methods 6 (1), 83-90, 2009 | 1070 | 2009 |
| A protein–protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration J Lim, T Hao, C Shaw, AJ Patel, G Szabó, JF Rual, CJ Fisk, N Li, ... Cell 125 (4), 801-814, 2006 | 988 | 2006 |
| Evidence for network evolution in an Arabidopsis interactome map AIM Consortium Science, 2011 | 968* | 2011 |
| Independently evolved virulence effectors converge onto hubs in a plant immune system network MS Mukhtar, AR Carvunis, M Dreze, P Epple, J Steinbrenner, J Moore, ... science 333 (6042), 596-601, 2011 | 918 | 2011 |
| Topological Control of p21WAF1/CIP1 Expression in Normal and Neoplastic Tissues WS El-Deiry, T Tokino, T Waldman, JD Oliner, VE Velculescu, M Burrell, ... Cancer research 55 (13), 2910-2919, 1995 | 809 | 1995 |
| A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection SD Shapira, I Gat-Viks, BOV Shum, A Dricot, MM de Grace, L Wu, ... Cell 139 (7), 1255-1267, 2009 | 753 | 2009 |
| Network modeling links breast cancer susceptibility and centrosome dysfunction MA Pujana, JDJ Han, LM Starita, KN Stevens, M Tewari, JS Ahn, ... Nature genetics 39 (11), 1338-1349, 2007 | 733 | 2007 |
| p53 Mutation and MDM2 Amplification in Human Soft Tissue Sarcomas FS Leach, T Tokino, P Meltzer, M Burrell, JD Oliner, S Smith, DE Hill, ... Cancer research 53 (10), 2231-2234, 1993 | 732 | 1993 |
| Integrative genomic approaches identify IKBKE as a breast cancer oncogene JS Boehm, JJ Zhao, J Yao, SY Kim, R Firestein, IF Dunn, SK Sjostrom, ... Cell 129 (6), 1065-1079, 2007 | 722 | 2007 |
| Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin JN Sarkaria, RS Tibbetts, EC Busby, AP Kennedy, DE Hill, RT Abraham Cancer research 58 (19), 4375-4382, 1998 | 664 | 1998 |
