| Angiogenesis in cancer and other diseases P Carmeliet, RK Jain nature 407 (6801), 249-257, 2000 | 12139 | 2000 |
| Photodynamic therapy for cancer DE Dolmans, D Fukumura, RK Jain Nature reviews cancer 3 (5), 380-387, 2003 | 7653 | 2003 |
| Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy RK Jain Science 307 (5706), 58-62, 2005 | 6619 | 2005 |
| Molecular mechanisms and clinical applications of angiogenesis P Carmeliet, RK Jain Nature 473 (7347), 298-307, 2011 | 6324 | 2011 |
| Understanding the tumor immune microenvironment (TIME) for effective therapy M Binnewies, EW Roberts, K Kersten, V Chan, DF Fearon, M Merad, ... Nature medicine 24 (5), 541-550, 2018 | 4715 | 2018 |
| Delivering nanomedicine to solid tumors RK Jain, T Stylianopoulos Nature reviews Clinical oncology 7 (11), 653-664, 2010 | 3617 | 2010 |
| Molecular regulation of vessel maturation RK Jain Nature medicine 9 (6), 685-693, 2003 | 3451 | 2003 |
| Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis P Carmeliet, Y Dor, JM Herbert, D Fukumura, K Brusselmans, ... Nature 394 (6692), 485-490, 1998 | 3449 | 1998 |
| Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment SK Hobbs, WL Monsky, F Yuan, WG Roberts, L Griffith, VP Torchilin, ... Proceedings of the National Academy of Sciences 95 (8), 4607-4612, 1998 | 3065 | 1998 |
| A framework for advancing our understanding of cancer-associated fibroblasts E Sahai, I Astsaturov, E Cukierman, DG DeNardo, M Egeblad, RM Evans, ... Nature Reviews Cancer 20 (3), 174-186, 2020 | 2996 | 2020 |
| Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy RK Jain Nature medicine 7 (9), 987-989, 2001 | 2741 | 2001 |
| Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer CG Willett, Y Boucher, E Di Tomaso, DG Duda, LL Munn, RT Tong, ... Nature medicine 10 (2), 145-147, 2004 | 2521 | 2004 |
| Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size F Yuan, M Dellian, D Fukumura, M Leunig, DA Berk, VP Torchilin, RK Jain Cancer research 55 (17), 3752-3756, 1995 | 2333 | 1995 |
| AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients TT Batchelor, AG Sorensen, E di Tomaso, WT Zhang, DG Duda, ... Cancer cell 11 (1), 83-95, 2007 | 2124 | 2007 |
| Openings between defective endothelial cells explain tumor vessel leakiness H Hashizume, P Baluk, S Morikawa, JW McLean, G Thurston, S Roberge, ... The American journal of pathology 156 (4), 1363-1380, 2000 | 2118 | 2000 |
| Interstitial pH and pO2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation G Helmlinger, F Yuan, M Dellian, RK Jain Nature medicine 3 (2), 177-182, 1997 | 2047 | 1997 |
| Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study NM Kuderer, TK Choueiri, DP Shah, Y Shyr, SM Rubinstein, DR Rivera, ... The Lancet 395 (10241), 1907-1918, 2020 | 1953 | 2020 |
| Transport of molecules in the tumor interstitium: a review RK Jain Cancer research 47 (12), 3039-3051, 1987 | 1935 | 1987 |
| Determinants of tumor blood flow: a review RK Jain Cancer research 48 (10), 2641-2658, 1988 | 1931 | 1988 |
| Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases P Carmeliet, RK Jain Nature reviews Drug discovery 10 (6), 417-427, 2011 | 1904 | 2011 |
Dan G. Duda, DMD, PhDProfessor of Radiation Oncology, Massachusetts General Hospital and Harvard Medical SchoolVerified email at partners.org
