| RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway YH Chiu, JB MacMillan, ZJ Chen Cell 138 (3), 576-591, 2009 | 1448 | 2009 |
| Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1 Q Sun, YP Carrasco, Y Hu, X Guo, H Mirzaei, J MacMillan, YM Chook Proceedings of the National Academy of Sciences 110 (4), 1303-1308, 2013 | 263 | 2013 |
| The ammosamides: structures of cell cycle modulators from a marine-derived Streptomyces species CC Hughes, JB MacMillan, SP Gaudêncio, PR Jensen, W Fenical Angewandte Chemie (International ed. in English) 48 (4), 725, 2009 | 219 | 2009 |
| Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan C Wang, H Niederstrasser, PM Douglas, R Lin, J Jaramillo, Y Li, ... Nature communications 8 (1), 2270, 2017 | 152 | 2017 |
| Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor JL Rogers, L Bayeh, TH Scheuermann, J Longgood, J Key, J Naidoo, ... Journal of medicinal chemistry 56 (4), 1739-1747, 2013 | 149 | 2013 |
| Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection MG Derebe, CM Zlatkov, S Gattu, KA Ruhn, S Vaishnava, GE Diehl, ... Elife 3, e03206, 2014 | 142 | 2014 |
| Lobocyclamides A−C, Lipopeptides from a Cryptic Cyanobacterial Mat Containing Lyngbya confervoides JB MacMillan, MA Ernst-Russell, JS De Ropp, TF Molinski The Journal of organic chemistry 67 (23), 8210-8215, 2002 | 136 | 2002 |
| Chemistry-first approach for nomination of personalized treatment in lung cancer EA McMillan, MJ Ryu, CH Diep, S Mendiratta, JR Clemenceau, ... Cell 173 (4), 864-878. e29, 2018 | 134 | 2018 |
| Ammosamides A and B target myosin CC Hughes, JB MacMillan, SP Gaudêncio, W Fenical, JJ La Clair Angewandte Chemie 121 (4), 742-746, 2009 | 131 | 2009 |
| The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research JB McAlpine, SN Chen, A Kutateladze, JB MacMillan, G Appendino, ... Natural product reports 36 (1), 35-107, 2019 | 114 | 2019 |
| Lodopyridone, a structurally unprecedented alkaloid from a marine actinomycete KN Maloney, JB MacMillan, CA Kauffman, PR Jensen, AG DiPasquale, ... Organic letters 11 (23), 5422-5424, 2009 | 109 | 2009 |
| The serotonin neurotransmitter modulates virulence of enteric pathogens A Kumar, RM Russell, R Pifer, Z Menezes-Garcia, S Cuesta, S Narayanan, ... Cell host & microbe 28 (1), 41-53. e8, 2020 | 99 | 2020 |
| Structural and mechanistic roles of novel chemical ligands on the SdiA quorum-sensing transcription regulator Y Nguyen, NX Nguyen, JL Rogers, J Liao, JB MacMillan, Y Jiang, ... MBio 6 (2), 10.1128/mbio. 02429-14, 2015 | 94 | 2015 |
| Metabolite regulation of nuclear localization of carbohydrate-response element-binding protein (ChREBP): role of AMP as an allosteric inhibitor S Sato, H Jung, T Nakagawa, R Pawlosky, T Takeshima, WR Lee, ... Journal of Biological Chemistry 291 (20), 10515-10527, 2016 | 89 | 2016 |
| Caylobolide A, a Unique 36-Membered Macrolactone from a Bahamian Lyngbya majuscula JB MacMillan, TF Molinski Organic Letters 4 (9), 1535-1538, 2002 | 88 | 2002 |
| Using functional signature ontology (FUSION) to identify mechanisms of action for natural products MB Potts, HS Kim, KW Fisher, Y Hu, YP Carrasco, GB Bulut, YH Ou, ... Science signaling 6 (297), ra90-ra90, 2013 | 87 | 2013 |
| Precursor-directed generation of amidine containing ammosamide analogs: Ammosamides E–P E Pan, NW Oswald, AG Legako, JM Life, BA Posner, JB MacMillan Chemical Science 4 (1), 482-488, 2013 | 87 | 2013 |
| Tropolactones A–D, four meroterpenoids from a marine-derived fungus of the genus Aspergillus M Cueto, JB MacMillan, PR Jensen, W Fenical Phytochemistry 67 (16), 1826-1831, 2006 | 85 | 2006 |
| Isoform-selective and stereoselective inhibition of hypoxia inducible factor-2 TH Scheuermann, D Stroud, CE Sleet, L Bayeh, C Shokri, H Wang, ... Journal of Medicinal Chemistry 58 (15), 5930-5941, 2015 | 84 | 2015 |
| Ikarugamycin: a natural product inhibitor of clathrin‐mediated endocytosis SR Elkin, NW Oswald, DK Reed, M Mettlen, JB MacMillan, SL Schmid Traffic 17 (10), 1139-1149, 2016 | 82 | 2016 |
