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T. Reid Alderson
T. Reid Alderson
Tenure-Track Group Leader, Helmholtz Munich
Verified email at helmholtz-munich.de
Title
Cited by
Cited by
Year
NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function
TR Alderson, LE Kay
Cell 184 (3), 577-595, 2021
1532021
Dynamical structures of Hsp70 and Hsp70-Hsp40 complexes
TR Alderson, JH Kim, JL Markley
Structure 24 (7), 1014-1030, 2016
1242016
Systematic identification of conditionally folded intrinsically disordered regions by AlphaFold2
TR Alderson#, I Pritišanac#, Đ Kolarić, AM Moses, JD Forman-Kay
Proceedings of the National Academy of Sciences 120 (44), e2304302120, 2023
1202023
Local unfolding of the HSP27 monomer regulates chaperone activity
TR Alderson, J Roche, HY Gastall, DM Dias, I Pritišanac, J Ying, A Bax, ...
Nature Communications 10 (1), 1068, 2019
1062019
Biophysical characterization of α-synuclein and its controversial structure
TR Alderson, JL Markley
Intrinsically Disordered Proteins 1 (1), e26255, 2013
1022013
Unveiling invisible protein states with NMR spectroscopy
TR Alderson, LE Kay
Current Opinion in Structural Biology 60, 39-49, 2020
1002020
Propensity for cis-proline formation in unfolded proteins
TR Alderson, JH Lee, C Charlier, J Ying, A Bax
ChemBioChem 19 (1), 37, 2018
802018
Study of protein folding under native conditions by rapidly switching the hydrostatic pressure inside an NMR sample cell
C Charlier, TR Alderson, JM Courtney, J Ying, P Anfinrud, A Bax
Proceedings of the National Academy of Sciences 115 (18), E4169-E4178, 2018
762018
HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C
MP Collier, TR Alderson, CP de Villiers, D Nicholls, HY Gastall, TM Allison, ...
Science Advances 5 (5), eaav8421, 2019
662019
Automatic assignment of methyl-NMR spectra of supramolecular machines using graph theory
I Pritisanac, MT Degiacomi, TR Alderson, MG Carneiro, E Ab, G Siegal, ...
Journal of the American Chemical Society 139 (28), 9523-9533, 2017
642017
Tangled web of interactions among proteins involved in iron–sulfur cluster assembly as unraveled by NMR, SAXS, chemical crosslinking, and functional studies
JH Kim, JR Bothe, TR Alderson, JL Markley
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (6), 1416-1428, 2015
502015
Automatic structure-based NMR methyl resonance assignment in large proteins
I Pritišanac, JM Würz, TR Alderson, P Güntert
Nature Communications 10, 4922, 2019
442019
Automated assignment of methyl NMR spectra from large proteins
I Pritišanac, TR Alderson, P Güntert
Progress in Nuclear Magnetic Resonance Spectroscopy 118, 54-73, 2020
352020
Monitoring hydrogen exchange during protein folding by fast pressure jump NMR spectroscopy
TR Alderson*, C Charlier*, DA Torchia, P Anfinrud, A Bax
Journal of the American Chemical Society 139 (32), 11036-11039, 2017
352017
Proline isomerization in the C-terminal region of HSP27
TR Alderson, JLP Benesch, AJ Baldwin
Cell Stress and Chaperones 22 (4), 639-651, 2017
352017
The Specialized Hsp70 (HscA) Interdomain Linker Binds to Its Nucleotide-Binding Domain and Stimulates ATP Hydrolysis in Both cis and trans Configurations
TR Alderson, JH Kim, K Cai, RO Frederick, M Tonelli, JL Markley
Biochemistry 53 (46), 7148-7159, 2014
332014
Nucleotide-dependent interactions within a specialized Hsp70/Hsp40 complex involved in Fe–S cluster biogenesis
JH Kim, TR Alderson, RO Frederick, JL Markley
Journal of the American Chemical Society 136 (33), 11586-11589, 2014
302014
Conditional disorder in small heat-shock proteins
TR Alderson, J Ying, A Bax, JLP Benesch, AJ Baldwin
Journal of Molecular Biology 432 (9), 3033-3049, 2020
282020
A weakened interface in the P182L variant of HSP27 associated with severe Charcot‐Marie‐Tooth neuropathy causes aberrant binding to interacting proteins
TR Alderson*, E Adriaenssens*, B Asselbergh, I Pritišanac, J Van Lent, ...
The EMBO Journal, e103811, 2021
24*2021
Monitoring 15N Chemical Shifts During Protein Folding by Pressure-Jump NMR
C Charlier, JM Courtney, TR Alderson, P Anfinrud, A Bax
Journal of the American Chemical Society 140 (26), 8096-8099, 2018
222018
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