| Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity SM Kim, JR DeFazio, SK Hyoju, K Sangani, R Keskey, MA Krezalek, ... Nature communications 11 (1), 2354, 2020 | 119 | 2020 |
| The gut microbiome and the mechanism of surgical infection JC Alverdy, SK Hyoju, M Weigerinck, JA Gilbert Journal of British Surgery 104 (2), e14-e23, 2017 | 115 | 2017 |
| Western-type diet influences mortality from necrotising pancreatitis and demonstrates a central role for butyrate FF van den Berg, D van Dalen, SK Hyoju, HC van Santvoort, ... Gut 70 (5), 915-927, 2021 | 111 | 2021 |
| Can methicillin-resistant Staphylococcus aureus silently travel from the gut to the wound and cause postoperative infection? Modeling the “Trojan Horse Hypothesis” MA Krezalek, S Hyoju, A Zaborin, E Okafor, L Chandrasekar, V Bindokas, ... Annals of surgery 267 (4), 749-758, 2018 | 105 | 2018 |
| Oral polyphosphate suppresses bacterial collagenase production and prevents anastomotic leak due to Serratia marcescens and Pseudomonas aeruginosa SK Hyoju, RE Klabbers, M Aaron, MA Krezalek, A Zaborin, M Wiegerinck, ... Annals of surgery 267 (6), 1112-1118, 2018 | 86 | 2018 |
| Inhibition of the gut enzyme intestinal alkaline phosphatase may explain how aspartame promotes glucose intolerance and obesity in mice SS Gul, ARL Hamilton, AR Munoz, T Phupitakphol, W Liu, SK Hyoju, ... Applied Physiology, Nutrition, and Metabolism 42 (1), 77-83, 2017 | 77 | 2017 |
| Western diet promotes intestinal colonization by collagenolytic microbes and promotes tumor formation after colorectal surgery S Gaines, JB van Praagh, AJ Williamson, RA Jacobson, S Hyoju, ... Gastroenterology 158 (4), 958-970. e2, 2020 | 69 | 2020 |
| Low-fat/high-fibre diet prehabilitation improves anastomotic healing via the microbiome: an experimental model SK Hyoju, C Adriaansens, K Wienholts, A Sharma, R Keskey, W Arnold, ... Journal of British Surgery 107 (6), 743-755, 2020 | 67 | 2020 |
| Novel de novo synthesized phosphate carrier compound ABA-PEG20k-Pi20 suppresses collagenase production in Enterococcus faecalis and prevents colonic … M Wiegerinck, SK Hyoju, J Mao, A Zaborin, C Adriaansens, E Salzman, ... Journal of British Surgery 105 (10), 1368-1376, 2018 | 57 | 2018 |
| Mice fed an obesogenic western diet, administered antibiotics, and subjected to a sterile surgical procedure develop lethal septicemia with multidrug-resistant pathobionts SK Hyoju, A Zaborin, R Keskey, A Sharma, W Arnold, F van den Berg, ... MBio 10 (4), 10.1128/mbio. 00903-19, 2019 | 44 | 2019 |
| The intestinal microbiome and surgical disease MA Krezalek, KB Skowron, KL Guyton, B Shakhsheer, S Hyoju, ... Current problems in surgery 53 (6), 257-293, 2016 | 40 | 2016 |
| Critical role of microbiota within cecal crypts on the regenerative capacity of the intestinal epithelium following surgical stress A Zaborin, M Krezalek, S Hyoju, JR Defazio, N Setia, N Belogortseva, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 312 (2 …, 2017 | 38 | 2017 |
| Defining microbiome readiness for surgery: dietary prehabilitation and stool biomarkers as predictive tools to improve outcome R Keskey, E Papazian, A Lam, T Toni, S Hyoju, R Thewissen, A Zaborin, ... Annals of surgery 276 (5), e361-e369, 2022 | 35 | 2022 |
| Enterococcus faecalis exploits the human fibrinolytic system to drive excess collagenolysis: implications in gut healing and identification of druggable targets RA Jacobson, K Wienholts, AJ Williamson, S Gaines, S Hyoju, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 318 (1 …, 2020 | 34 | 2020 |
| Spatial compartmentalization of the microbiome between the lumen and crypts is lost in the murine cecum following the process of surgery, including overnight fasting and … A Zaborin, B Penalver Bernabe, R Keskey, N Sangwan, S Hyoju, N Gottel, ... Msystems 5 (3), 10.1128/msystems. 00377-20, 2020 | 25 | 2020 |
| Prevention of anastomotic leak via local application of tranexamic acid to target bacterial-mediated plasminogen activation: a practical solution to a complex problem RA Jacobson, AJ Williamson, K Wienholts, S Gaines, S Hyoju, H van Goor, ... Annals of surgery 274 (6), e1038-e1046, 2021 | 20 | 2021 |
| Sustained Release of Polyphosphate from Hydrogel Nanoparticles Suppresses Bacterial Collagenase and Biofilm Formation In Vitro D Nichols, M Pimentel, FTP Borges, SK Hyojuh, F Teymour, SH Hong, ... Frontiers in Bioengineering and Biotechnology 7, 153, 2019 | 16 | 2019 |
| A novel nonantibiotic gut-directed strategy to prevent surgical site infections SK Hyoju, R Keskey, G Castillo, K Machutta, A Zaborin, O Zaborina, ... Annals of surgery 276 (3), 472-481, 2022 | 12 | 2022 |
| SARS-CoV-2 and the sympathetic immune response: Dampening inflammation with antihypertensive drugs (Clonidine and Propranolol) SK Hyoju, O Zaborina, H van Goor Medical Hypotheses 144, 110039, 2020 | 12 | 2020 |
| Transfer of clinical breast examination skills to female community health volunteers in Nepal SK Hyoju, CS Agrawal, PK Pokhrel, S Agrawal Asian Pac J Cancer Prev 12, 3353-3356, 2011 | 12 | 2011 |
John AlverdyProfessor of SurgeryVerified email at surgery.bsd.uchicago.edu