| Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3631 | 2010 |
| Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man GG Gibson, NJ Plant, KE Swales, A Ayrton, W El-Sankary Xenobiotica 32 (3), 165-206, 2002 | 257 | 2002 |
| From genes to genomes: concepts and applications of DNA technology JW Dale, M Von Schantz, N Plant John Wiley & Sons, 2011 | 236 | 2011 |
| Fatty acid binding proteins: tissue-specific functions in health and disease AE Thumser, JB Moore, NJ Plant Current Opinion in Clinical Nutrition & Metabolic Care 17 (2), 124-129, 2014 | 207 | 2014 |
| Characterization of rhodamine-123 as a tracer dye for use in in vitro drug transport assays S Forster, AE Thumser, SR Hood, N Plant PloS one 7 (3), e33253, 2012 | 206 | 2012 |
| Seizure control by ketogenic diet-associated medium chain fatty acids P Chang, N Terbach, N Plant, PE Chen, MC Walker, RSB Williams Neuropharmacology 69, 105-114, 2013 | 174 | 2013 |
| Strategies for using in vitro screens in drug metabolism N Plant Drug discovery today 9 (7), 328-336, 2004 | 174 | 2004 |
| Use of a reporter gene assay to predict and rank the potency and efficacy of CYP3A4 inducers W El-Sankary, GG Gibson, A Ayrton, N Plant Drug Metabolism and Disposition 29 (11), 1499-1504, 2001 | 138 | 2001 |
| The human cytochrome P450 sub-family: transcriptional regulation, inter-individual variation and interaction networks N Plant Biochimica et Biophysica Acta (BBA)-General Subjects 1770 (3), 478-488, 2007 | 134 | 2007 |
| Mixed chelate copper complex, Casiopeina IIgly®, binds and degrades nucleic acids: A mechanism of cytotoxicity A Rivero-Müller, A De Vizcaya-Ruiz, N Plant, L Ruiz, M Dobrota Chemico-Biological Interactions 165 (3), 189-199, 2007 | 133 | 2007 |
| Non-coplanar polychlorinated biphenyls (PCBs) are direct agonists for the human pregnane-X receptor and constitutive androstane receptor, and activate target gene expression in … F Al-Salman, N Plant Toxicology and applied pharmacology 263 (1), 7-13, 2012 | 118 | 2012 |
| Regulation of the CYP3A4 gene by hydrocortisone and xenobiotics: role of the glucocorticoid and pregnane X receptors W El-Sankary, NJ Plant, GG Gibson, DJ Moore Drug Metabolism and Disposition 28 (5), 493-496, 2000 | 105 | 2000 |
| EGF mediates monocyte chemotaxis and macrophage proliferation and EGF receptor is expressed in atherosclerotic plaques DJ Lamb, H Modjtahedi, NJ Plant, GAA Ferns Atherosclerosis 176 (1), 21-26, 2004 | 98 | 2004 |
| Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs DR Bell, NJ Plant, CG Rider, L Na, S Brown, I Ateitalla, SK Acharya, ... Biochemical Journal 294 (1), 173-180, 1993 | 97 | 1993 |
| Glucocorticoid-mediated induction of CYP3A4 is decreased by disruption of a protein: DNA interaction distinct from the pregnane X receptor response element W El-Sankary, V Bombail, GG Gibson, N Plant Drug metabolism and disposition 30 (9), 1029-1034, 2002 | 90 | 2002 |
| Transcriptional regulation of the PXR gene: identification and characterization of a functional peroxisome proliferator-activated receptor α binding site within the proximal … S Aouabdi, G Gibson, N Plant Drug metabolism and disposition 34 (1), 138-144, 2006 | 77 | 2006 |
| The statin class of HMG-CoA reductase inhibitors demonstrate differential activation of the nuclear receptors PXR, CAR and FXR, as well as their downstream target genes K Howe, F Sanat, AE Thumser, T Coleman, N Plant Xenobiotica 41 (7), 519-529, 2011 | 71 | 2011 |
| Role of Sp1, C/EBPα, HNF3, and PXR in the basal-and xenobiotic-mediated regulation of the CYP3A4 gene V Bombail, K Taylor, GG Gibson, N Plant Drug metabolism and disposition 32 (5), 525-535, 2004 | 69 | 2004 |
| Evaluation of the toxicological relevance of CYP3A4 induction. NJ Plant, GG Gibson Current opinion in drug discovery & development 6 (1), 50-56, 2003 | 68 | 2003 |
| Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and … DS Pushparajah, M Umachandran, T Nazir, KE Plant, N Plant, DFV Lewis, ... Toxicology in Vitro 22 (1), 128-145, 2008 | 64 | 2008 |