Both CRISPR/Cas‐based nucleases and nickases can be used efficiently for genome engineering in Arabidopsis thaliana F Fauser, S Schiml, H Puchta The Plant Journal 79 (2), 348-359, 2014 | 870 | 2014 |
The CRISPR/Cas system can be used as nuclease for in planta gene targeting and as paired nickases for directed mutagenesis in Arabidopsis resulting in heritable progeny S Schiml, F Fauser, H Puchta The Plant Journal 80 (6), 1139-1150, 2014 | 430 | 2014 |
Synthetic nucleases for genome engineering in plants: prospects for a bright future H Puchta, F Fauser The Plant Journal 78 (5), 727-741, 2014 | 318 | 2014 |
Highly efficient heritable plant genome engineering using Cas9 orthologues from Streptococcus thermophilus and Staphylococcus aureus J Steinert, S Schiml, F Fauser, H Puchta The Plant Journal 84 (6), 1295-1305, 2015 | 289 | 2015 |
A genome-wide algal mutant library and functional screen identifies genes required for eukaryotic photosynthesis X Li, W Patena, F Fauser, RE Jinkerson, S Saroussi, MT Meyer, N Ivanova, ... Nature Genetics, 2019 | 275 | 2019 |
In planta gene targeting F Fauser, N Roth, M Pacher, G Ilg, R Sánchez-Fernández, C Biesgen, ... Proceedings of the National Academy of Sciences 109 (19), 7535-7540, 2012 | 252 | 2012 |
Gene targeting in plants: 25 years later H Puchta, F Fauser Int J Dev Biol 57 (6-8), 629-37, 2013 | 223 | 2013 |
DNA recombination in somatic plant cells: mechanisms and evolutionary consequences A Knoll, F Fauser, H Puchta Chromosome research 22 (2), 191-201, 2014 | 115 | 2014 |
Repair of adjacent single-strand breaks is often accompanied by the formation of tandem sequence duplications in plant genomes S Schiml, F Fauser, H Puchta Proceedings of the National Academy of Sciences 113 (26), 7266-7271, 2016 | 82 | 2016 |
Systematic characterization of gene function in the photosynthetic alga Chlamydomonas reinhardtii F Fauser, J Vilarrasa-Blasi, M Onishi, S Ramundo, W Patena, M Millican, ... Nature Genetics, 1-10, 2022 | 65 | 2022 |
Enhancing gene editing specificity by attenuating DNA cleavage kinetics JC Miller, DP Patil, DF Xia, CB Paine, F Fauser, HW Richards, DA Shivak, ... Nature biotechnology 37 (8), 945-952, 2019 | 57 | 2019 |
CRISPR/Cas-mediated site-specific mutagenesis in Arabidopsis thaliana using Cas9 nucleases and paired nickases S Schiml, F Fauser, H Puchta Chromosome and Genomic Engineering in Plants, 111-122, 2016 | 46 | 2016 |
Endogenous sequence patterns predispose the repair modes of CRISPR/Cas9‐induced DNA double‐stranded breaks in Arabidopsis thaliana GTH Vu, HX Cao, F Fauser, B Reiss, H Puchta, I Schubert The Plant Journal 92 (1), 57-67, 2017 | 43 | 2017 |
Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer L Cato, A Neeb, A Sharp, V Buzón, SB Ficarro, L Yang, C Muhle-Goll, ... eLife 6, e27159, 2017 | 38 | 2017 |
Double-Strand Break Repair and Its Application to Genome Engineering in Plants H Puchta, F Fauser Advances in New Technology for Targeted Modification of Plant Genomes, 1-20, 2015 | 11 | 2015 |
Systematic characterization of gene function in a photosynthetic organism J Vilarrasa-Blasi, F Fauser, M Onishi, S Ramundo, W Patena, M Millican, ... bioRxiv, 2020 | 9 | 2020 |
CRISPR/Cas-Mediated In Planta Gene Targeting S Schiml, F Fauser, H Puchta Plant Genomics, 3-11, 2017 | 9 | 2017 |
Plant Chemical Genomics F Fauser, M Jonikas | 4 | 2018 |
Multi-omics analysis of green lineage osmotic stress pathways unveils crucial roles of different cellular compartments J Vilarrasa-Blasi, T Vellosillo, RE Jinkerson, F Fauser, T Xiang, BB Minkoff, ... Nature communications 15 (1), 5988, 2024 | 3 | 2024 |
Compact zinc finger architecture utilizing toxin-derived cytidine deaminases for highly efficient base editing in human cells F Fauser, BN Kadam, S Arangundy-Franklin, JE Davis, V Vaidya, ... Nature Communications 15 (1), 1181, 2024 | 3 | 2024 |