| X-ray structures and mechanism of the human serotonin transporter JA Coleman, EM Green, E Gouaux Nature 532 (7599), 334-339, 2016 | 679 | 2016 |
| Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport JA Coleman, D Yang, Z Zhao, PC Wen, C Yoshioka, E Tajkhorshid, ... Nature 569 (7754), 141-145, 2019 | 238 | 2019 |
| Localization, purification, and functional reconstitution of the P4-ATPase Atp8a2, a phosphatidylserine flippase in photoreceptor disc membranes JA Coleman, MCM Kwok, RS Molday Journal of Biological Chemistry 284 (47), 32670-32679, 2009 | 212 | 2009 |
| Mammalian P4-ATPases and ABC transporters and their role in phospholipid transport JA Coleman, F Quazi, RS Molday Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2013 | 165 | 2013 |
| Critical role of the β-subunit CDC50A in the stable expression, assembly, subcellular localization, and lipid transport activity of the P4-ATPase ATP8A2 JA Coleman, RS Molday Journal of Biological Chemistry 286 (19), 17205-17216, 2011 | 148 | 2011 |
| Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases LM van der Velden, CGK Wichers, AED Van Breevoort, JA Coleman, ... Journal of Biological Chemistry 285 (51), 40088-40096, 2010 | 148 | 2010 |
| Structural basis for recognition of diverse antidepressants by the human serotonin transporter JA Coleman, E Gouaux Nature structural & molecular biology 25 (2), 170-175, 2018 | 142 | 2018 |
| Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2 AL Vestergaard, JA Coleman, T Lemmin, SA Mikkelsen, LL Molday, ... Proceedings of the National Academy of Sciences 111 (14), E1334-E1343, 2014 | 122 | 2014 |
| Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P4-ATPase ATP8A2 JA Coleman, AL Vestergaard, RS Molday, B Vilsen, J Peter Andersen Proceedings of the National Academy of Sciences 109 (5), 1449-1454, 2012 | 107 | 2012 |
| Chemical and structural investigation of the paroxetine-human serotonin transporter complex JA Coleman, V Navratna, D Antermite, D Yang, JA Bull, E Gouaux eLife, 2020 | 73 | 2020 |
| Proteomic analysis and functional characterization of P4-ATPase phospholipid flippases from murine tissues J Wang, LL Molday, T Hii, JA Coleman, T Wen, JP Andersen, RS Molday Scientific reports 8 (1), 10795, 2018 | 72 | 2018 |
| Phospholipid flippase ATP8A2 is required for normal visual and auditory function and photoreceptor and spiral ganglion cell survival JA Coleman, X Zhu, HR Djajadi, LL Molday, RS Smith, RT Libby, ... Journal of cell science 127 (5), 1138-1149, 2014 | 70 | 2014 |
| The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter P Plenge, D Yang, K Salomon, L Laursen, IE Kalenderoglou, AH Newman, ... Nature Communications 12 (1), 5063, 2021 | 69 | 2021 |
| Interaction and localization of the retinitis pigmentosa protein RP2 and NSF in retinal photoreceptor cells JM Holopainen, CL Cheng, LL Molday, G Johal, J Coleman, F Dyka, T Hii, ... Biochemistry 49 (35), 7439-7447, 2010 | 45 | 2010 |
| Structures of highly flexible intracellular domain of human α7 nicotinic acetylcholine receptor V Bondarenko, MM Wells, Q Chen, TS Tillman, K Singewald, MJ Lawless, ... Nature communications 13 (1), 793, 2022 | 39 | 2022 |
| Thermostabilization of the human serotonin transporter in an antidepressant-bound conformation EM Green, JA Coleman, E Gouaux PloS one 10 (12), e0145688, 2015 | 21 | 2015 |
| Extracellular loops of the serotonin transporter act as a selectivity filter for drug binding E Esendir, V Burtscher, JA Coleman, R Zhu, E Gouaux, M Freissmuth, ... Journal of Biological Chemistry 297 (1), 2021 | 15 | 2021 |
| Thermostabilization, expression, purification, and crystallization of the human serotonin transporter bound to S-citalopram JA Coleman, EM Green, E Gouaux Journal of visualized experiments: JoVE, 54792, 2016 | 15 | 2016 |
| Specific mutations in mammalian P4-ATPase ATP8A2 catalytic subunit entail differential glycosylation of the accessory CDC50A subunit AL Vestergaard, SA Mikkelsen, JA Coleman, RS Molday, B Vilsen, ... FEBS letters 589 (24), 3908-3914, 2015 | 15 | 2015 |
| SARS-CoV-2 spike protein downregulates cell surface α7nAChR through a helical motif in the spike neck TS Tillman, Q Chen, V Bondarenko, JA Coleman, Y Xu, P Tang ACS Chemical Neuroscience 14 (4), 689-698, 2023 | 13 | 2023 |