An epigenetic biomarker of aging for lifespan and healthspan ME Levine, AT Lu, A Quach, BH Chen, TL Assimes, S Bandinelli, L Hou, ... Aging (albany NY) 10 (4), 573, 2018 | 2428 | 2018 |
Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population ME Levine, JA Suarez, S Brandhorst, P Balasubramanian, CW Cheng, ... Cell metabolism 19 (3), 407-417, 2014 | 1145 | 2014 |
DNA methylation-based measures of biological age: meta-analysis predicting time to death BH Chen, RE Marioni, E Colicino, MJ Peters, CK Ward-Caviness, PC Tsai, ... Aging (Albany NY) 8 (9), 1844, 2016 | 1061 | 2016 |
Quantification of biological aging in young adults DW Belsky, A Caspi, R Houts, HJ Cohen, DL Corcoran, A Danese, ... Proceedings of the National Academy of Sciences 112 (30), E4104-E4110, 2015 | 1031 | 2015 |
Modeling the rate of senescence: can estimated biological age predict mortality more accurately than chronological age? ME Levine Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2013 | 765 | 2013 |
An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease S Horvath, M Gurven, ME Levine, BC Trumble, H Kaplan, H Allayee, ... Genome biology 17, 1-23, 2016 | 729 | 2016 |
Epigenetic clock analysis of diet, exercise, education, and lifestyle factors A Quach, ME Levine, T Tanaka, AT Lu, BH Chen, L Ferrucci, B Ritz, ... Aging (albany NY) 9 (2), 419, 2017 | 718 | 2017 |
Reprogramming to recover youthful epigenetic information and restore vision Y Lu, B Brommer, X Tian, A Krishnan, M Meer, C Wang, DL Vera, Q Zeng, ... Nature 588 (7836), 124-129, 2020 | 673 | 2020 |
Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning ME Levine, AT Lu, DA Bennett, S Horvath Aging (Albany NY) 7 (12), 1198, 2015 | 482 | 2015 |
Menopause accelerates biological aging ME Levine, AT Lu, BH Chen, DG Hernandez, AB Singleton, L Ferrucci, ... Proceedings of the National Academy of Sciences 113 (33), 9327-9332, 2016 | 470 | 2016 |
Eleven telomere, epigenetic clock, and biomarker-composite quantifications of biological aging: do they measure the same thing? DW Belsky, TE Moffitt, AA Cohen, DL Corcoran, ME Levine, JA Prinz, ... American journal of epidemiology 187 (6), 1220-1230, 2018 | 413 | 2018 |
A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: a cohort study Z Liu, PL Kuo, S Horvath, E Crimmins, L Ferrucci, M Levine PLoS medicine 15 (12), e1002718, 2018 | 410 | 2018 |
A systematic review of biological, social and environmental factors associated with epigenetic clock acceleration L Oblak, J van der Zaag, AT Higgins-Chen, ME Levine, MP Boks Ageing research reviews 69, 101348, 2021 | 385 | 2021 |
DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative ME Levine, HD Hosgood, B Chen, D Absher, T Assimes, S Horvath Aging (Albany NY) 7 (9), 690, 2015 | 315 | 2015 |
Loneliness, eudaimonia, and the human conserved transcriptional response to adversity SW Cole, ME Levine, JMG Arevalo, J Ma, DR Weir, EM Crimmins Psychoneuroendocrinology 62, 11-17, 2015 | 252 | 2015 |
A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking AT Higgins-Chen, KL Thrush, Y Wang, CJ Minteer, PL Kuo, M Wang, ... Nature aging 2 (7), 644-661, 2022 | 234 | 2022 |
Time and the metrics of aging L Ferrucci, ME Levine, PL Kuo, EM Simonsick Circulation Research 123 (7), 740-744, 2018 | 222 | 2018 |
The impact of insulin resistance and inflammation on the association between sarcopenic obesity and physical functioning ME Levine, EM Crimmins Obesity 20 (10), 2101-2106, 2012 | 191 | 2012 |
Underlying features of epigenetic aging clocks in vivo and in vitro Z Liu, D Leung, K Thrush, W Zhao, S Ratliff, T Tanaka, LL Schmitz, ... Aging cell 19 (10), e13229, 2020 | 181 | 2020 |
GWAS of epigenetic aging rates in blood reveals a critical role for TERT AT Lu, L Xue, EL Salfati, BH Chen, L Ferrucci, D Levy, R Joehanes, ... Nature communications 9 (1), 387, 2018 | 178 | 2018 |