| Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase FS Buckner, CL Verlinde, AC La Flamme, WC Van Voorhis Antimicrobial agents and chemotherapy 40 (11), 2592-2597, 1996 | 627 | 1996 |
| Macromolecular Crystallography and Medicine WGJ Hol, CLMJ Verlinde International Tables for Crystallography F, 10-43, 2006 | 482* | 2006 |
| Structure-based drug design: progress, results and challenges CLMJ Verlinde, WGJ Hol Structure 2 (7), 577-587, 1994 | 381 | 1994 |
| Genomic-scale prioritization of drug targets: the TDR Targets database F Agüero, B Al-Lazikani, M Aslett, M Berriman, FS Buckner, RK Campbell, ... Nature reviews Drug discovery 7 (11), 900-907, 2008 | 369 | 2008 |
| High-affinity pentavalent ligands of Escherichia coli heat-labile enterotoxin by modular structure-based design E Fan, Z Zhang, WE Minke, Z Hou, CLMJ Verlinde, WGJ Hol Journal of the American Chemical Society 122 (11), 2663-2664, 2000 | 363 | 2000 |
| Glycolysis as a target for the design of new anti-trypanosome drugs CLMJ Verlinde, V Hannaert, C Blonski, M Willson, JJ Périé, ... Drug Resistance Updates 4 (1), 50-65, 2001 | 326 | 2001 |
| Missense mutations in the regulatory domain of PKCγ: a new mechanism for dominant nonepisodic cerebellar ataxia DH Chen, Z Brkanac, LMJC Verlinde, XJ Tan, L Bylenok, D Nochlin, ... The American Journal of Human Genetics 72 (4), 839-849, 2003 | 302 | 2003 |
| Five members of a novel Ca2+-binding protein (CABP) subfamily with similarity to calmodulin F Haeseleer, I Sokal, CLMJ Verlinde, H Erdjument-Bromage, P Tempst, ... Journal of Biological Chemistry 275 (2), 1247-1260, 2000 | 292 | 2000 |
| Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors KK Ojo, ET Larson, KR Keyloun, LJ Castaneda, AE DeRocher, ... Nature structural & molecular biology 17 (5), 602-607, 2010 | 197 | 2010 |
| Rational modification of a candidate cancer drug for use against Chagas disease JM Kraus, CLMJ Verlinde, M Karimi, GI Lepesheva, MH Gelb, FS Buckner Journal of medicinal chemistry 52 (6), 1639-1647, 2009 | 185 | 2009 |
| AB5 toxins: structures and inhibitor design E Fan, EA Merritt, CLMJ Verlinde, WGJ Hol Current opinion in structural biology 10 (6), 680-686, 2000 | 178 | 2000 |
| Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase AM Aronov, S Suresh, FS Buckner, WC Van Voorhis, CLMJ Verlinde, ... Proceedings of the National Academy of Sciences 96 (8), 4273-4278, 1999 | 177 | 1999 |
| Solution and crystallographic studies of branched multivalent ligands that inhibit the receptor-binding of cholera toxin Z Zhang, EA Merritt, M Ahn, C Roach, Z Hou, CLMJ Verlinde, WGJ Hol, ... Journal of the American Chemical Society 124 (44), 12991-12998, 2002 | 166 | 2002 |
| Alternatively spliced isoforms of the human constitutive androstane receptor SS Auerbach, R Ramsden, MA Stoner, C Verlinde, C Hassett, ... Nucleic acids research 31 (12), 3194-3207, 2003 | 158 | 2003 |
| Adenosine Analogues as Selective Inhibitors of Glyceraldehyde-3-phosphate Dehydrogenase of Trypanosomatidae via Structure-Based Drug Design JC Bressi, CLMJ Verlinde, AM Aronov, ML Shaw, SS Shin, LN Nguyen, ... Journal of medicinal chemistry 44 (13), 2080-2093, 2001 | 156 | 2001 |
| Three-dimensional structure of the diphtheria toxin repressor in complex with divalent cation co-repressors X Qiu, CLMJ Verlinde, S Zhang, MP Schmitt, RK Holmes, WGJ Hol Structure 3 (1), 87-100, 1995 | 153 | 1995 |
| Discovery of Potent and Selective Inhibitors of CDPK1 from C. parvum and T. gondii RC Murphy, KK Ojo, ET Larson, A Castellanos-Gonzalez, BGK Perera, ... ACS medicinal chemistry letters 1 (7), 331-335, 2010 | 150* | 2010 |
| Second generation analogues of the cancer drug clinical candidate tipifarnib for anti-Chagas disease drug discovery JM Kraus, HB Tatipaka, SA McGuffin, NK Chennamaneni, M Karimi, J Arif, ... Journal of medicinal chemistry 53 (10), 3887-3898, 2010 | 146 | 2010 |
| Structure-based exploration of the ganglioside GM1 binding sites of Escherichia coli heat-labile enterotoxin and cholera toxin for the discovery of receptor antagonists WE Minke, C Roach, WGJ Hol, CLMJ Verlinde Biochemistry 38 (18), 5684-5692, 1999 | 141 | 1999 |
| Crystal structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Leishmania mexicana: implications for structure-based drug design and a new position for the … H Kim, IK Feil, CLMJ Verlinde, PH Petra, WGJ Hol Biochemistry 34 (46), 14975-14986, 1995 | 140 | 1995 |
Wesley Van VoorhisProfessor of Medicine, Univ of WAVerified email at uw.edu
