| Dependence of critical micelle concentration of a zwitterionic detergent on ionic strength: implications in receptor solubilization A Chattopadhyay, KG Harikumar FEBS letters 391 (1-2), 199-202, 1996 | 163 | 1996 |
| Single-molecule FRET imaging of GPCR dimers in living cells WB Asher, P Geggier, MD Holsey, GT Gilmore, AK Pati, J Meszaros, ... Nature methods 18 (4), 397-405, 2021 | 161 | 2021 |
| Structure and function of Norrin in assembly and activation of a Frizzled 4–Lrp5/6 complex J Ke, KG Harikumar, C Erice, C Chen, X Gu, L Wang, N Parker, Z Cheng, ... Genes & development 27 (21), 2305-2319, 2013 | 145 | 2013 |
| Transmembrane segment IV contributes a functionally important interface for oligomerization of the Class II G protein-coupled secretin receptor KG Harikumar, DI Pinon, LJ Miller Journal of Biological Chemistry 282 (42), 30363-30372, 2007 | 123 | 2007 |
| Crystal structure of the Frizzled 4 receptor in a ligand-free state S Yang, Y Wu, TH Xu, PW de Waal, Y He, M Pu, Y Chen, ZJ DeBruine, ... Nature 560 (7720), 666-670, 2018 | 115 | 2018 |
| Differential effects of modification of membrane cholesterol and sphingolipids on the conformation, function, and trafficking of the G protein-coupled cholecystokinin receptor KG Harikumar, V Puri, RD Singh, K Hanada, RE Pagano, LJ Miller Journal of Biological Chemistry 280 (3), 2176-2185, 2005 | 95 | 2005 |
| Heterodimerization of type A and B cholecystokinin receptors enhance signaling and promote cell growth ZJ Cheng, KG Harikumar, EL Holicky, LJ Miller Journal of Biological Chemistry 278 (52), 52972-52979, 2003 | 90 | 2003 |
| Constitutive formation of oligomeric complexes between family BG protein-coupled vasoactive intestinal polypeptide and secretin receptors KG Harikumar, MM Morfis, CS Lisenbee, PM Sexton, LJ Miller Molecular pharmacology 69 (1), 363-373, 2006 | 88 | 2006 |
| G-protein-dependent cell surface dynamics of the human serotonin1A receptor tagged to yellow fluorescent protein TJ Pucadyil, S Kalipatnapu, KG Harikumar, N Rangaraj, SS Karnik, ... Biochemistry 43 (50), 15852-15862, 2004 | 85 | 2004 |
| Structure of an AMPK complex in an inactive, ATP-bound state Y Yan, S Mukherjee, KG Harikumar, TS Strutzenberg, XE Zhou, ... Science 373 (6553), 413-419, 2021 | 81 | 2021 |
| Induced Association of μ Opioid (MOP) and Type 2 Cholecystokinin (CCK2) Receptors by Novel Bivalent Ligands Y Zheng, E Akgün, KG Harikumar, J Hopson, MD Powers, MM Lunzer, ... Journal of medicinal chemistry 52 (2), 247-258, 2009 | 81 | 2009 |
| Dimeric arrangement of the parathyroid hormone receptor and a structural mechanism for ligand-induced dissociation AA Pioszak, KG Harikumar, NR Parker, LJ Miller, HE Xu Journal of biological chemistry 285 (16), 12435-12444, 2010 | 79 | 2010 |
| Glucagon-like peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule allostery KG Harikumar, D Wootten, DI Pinon, C Koole, AM Ball, SGB Furness, ... Proceedings of the National Academy of Sciences 109 (45), 18607-18612, 2012 | 77 | 2012 |
| Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization ZJ DeBruine, J Ke, KG Harikumar, X Gu, P Borowsky, BO Williams, W Xu, ... Genes & development 31 (9), 916-926, 2017 | 72 | 2017 |
| Molecular basis of association of receptor activity-modifying protein 3 with the family BG protein-coupled secretin receptor KG Harikumar, J Simms, G Christopoulos, PM Sexton, LJ Miller Biochemistry 48 (49), 11773-11785, 2009 | 69 | 2009 |
| Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity JI Mobbs, MJ Belousoff, KG Harikumar, SJ Piper, X Xu, SGB Furness, ... PLoS biology 19 (6), e3001295, 2021 | 62 | 2021 |
| Role of cholesterol in ligand binding and G-protein coupling of serotonin1A receptors solubilized from bovine hippocampus A Chattopadhyay, M Jafurulla, S Kalipatnapu, TJ Pucadyil, KG Harikumar Biochemical and Biophysical Research Communications 327 (4), 1036-1041, 2005 | 61 | 2005 |
| Environment and mobility of a series of fluorescent reporters at the amino terminus of structurally related peptide agonists and antagonists bound to the cholecystokinin receptor KG Harikumar, DI Pinon, WS Wessels, FG Prendergast, LJ Miller Journal of Biological Chemistry 277 (21), 18552-18560, 2002 | 61 | 2002 |
| Differential sensitivity of types 1 and 2 cholecystokinin receptors to membrane cholesterol RM Potter, KG Harikumar, SV Wu, LJ Miller Journal of lipid research 53 (1), 137-148, 2012 | 60 | 2012 |
| Pattern of intra-family hetero-oligomerization involving the G-protein-coupled secretin receptor KG Harikumar, MM Morfis, PM Sexton, LJ Miller Journal of molecular neuroscience 36, 279-285, 2008 | 60 | 2008 |
Patrick SextonMonash UniversityVerified email at monash.edu
