| Intravascular danger signals guide neutrophils to sites of sterile inflammation B McDonald, K Pittman, GB Menezes, SA Hirota, I Slaba, ... Science 330 (6002), 362-366, 2010 | 1393 | 2010 |
| The NLRP3 inflammasome promotes renal inflammation and contributes to CKD A Vilaysane, J Chun, ME Seamone, W Wang, R Chin, S Hirota, Y Li, ... Journal of the American Society of Nephrology 21 (10), 1732-1744, 2010 | 625 | 2010 |
| NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis SA Hirota, J Ng, A Lueng, M Khajah, K Parhar, Y Li, V Lam, MS Potentier, ... Inflammatory bowel diseases 17 (6), 1359-1372, 2011 | 508 | 2011 |
| Activation of neuronal P2X7 receptor–pannexin-1 mediates death of enteric neurons during colitis BD Gulbransen, M Bashashati, SA Hirota, X Gui, JA Roberts, ... Nature medicine 18 (4), 600-604, 2012 | 450 | 2012 |
| Clostridium difficile Toxin–Induced Inflammation and Intestinal Injury Are Mediated by the Inflammasome J Ng, SA Hirota, O Gross, Y Li, A Ulke–Lemee, MS Potentier, LP Schenck, ... Gastroenterology 139 (2), 542-552. e3, 2010 | 271 | 2010 |
| The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter JA Hirota, SA Hirota, SM Warner, D Stefanowicz, F Shaheen, PL Beck, ... Journal of Allergy and Clinical Immunology 129 (4), 1116-1125. e6, 2012 | 217 | 2012 |
| The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin‐1β NA Bracey, PL Beck, DA Muruve, SA Hirota, J Guo, H Jabagi, JR Wright Jr, ... Experimental physiology 98 (2), 462-472, 2013 | 208 | 2013 |
| Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia FA Vicentini, CM Keenan, LE Wallace, C Woods, JB Cavin, AR Flockton, ... Microbiome 9, 1-24, 2021 | 207 | 2021 |
| Mechanisms of hydrogen‐peroxide‐induced biphasic response in rat mesenteric artery YJ Gao, S Hirota, DW Zhang, LJ Janssen, RMKW Lee British journal of pharmacology 138 (6), 1085-1092, 2003 | 146 | 2003 |
| IL-17A-mediated neutrophil recruitment limits expansion of segmented filamentous bacteria KL Flannigan, VL Ngo, D Geem, A Harusato, SA Hirota, CA Parkos, ... Mucosal immunology 10 (3), 673-684, 2017 | 138 | 2017 |
| Hyperglycaemic impairment of PAR2-mediated vasodilation: Prevention by inhibition of aortic endothelial sodium-glucose-co-Transporter-2 and minimizing oxidative stress M El-Daly, VKP Venu, M Saifeddine, K Mihara, S Kang, PWM Fedak, ... Vascular pharmacology 109, 56-71, 2018 | 122 | 2018 |
| Hypoxia-Inducible Factor Signaling Provides Protection in Clostridium difficile-Induced Intestinal Injury SA Hirota, K Fines, J Ng, D Traboulsi, J Lee, E Ihara, Y Li, WG Willmore, ... Gastroenterology 139 (1), 259-269. e3, 2010 | 120 | 2010 |
| The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection X Sun, SA Hirota Molecular immunology 63 (2), 193-202, 2015 | 113 | 2015 |
| Ionic mechanisms and Ca2+ handling in airway smooth muscle S Hirota, P Helli, LJ Janssen European Respiratory Journal 30 (1), 114-133, 2007 | 110 | 2007 |
| Vancomycin relieves mycophenolate mofetil–induced gastrointestinal toxicity by eliminating gut bacterial β-glucuronidase activity MR Taylor, KL Flannigan, H Rahim, A Mohamud, IA Lewis, SA Hirota, ... Science advances 5 (8), eaax2358, 2019 | 106 | 2019 |
| Pregnane X receptor agonists enhance intestinal epithelial wound healing and repair of the intestinal barrier following the induction of experimental colitis J Terc, A Hansen, L Alston, SA Hirota European journal of pharmaceutical sciences 55, 12-19, 2014 | 102 | 2014 |
| Giardia duodenalis infection reduces granulocyte infiltration in an in vivo model of bacterial toxin-induced colitis and attenuates inflammation in human intestinal tissue JA Cotton, JP Motta, LP Schenck, SA Hirota, PL Beck, AG Buret PloS one 9 (10), e109087, 2014 | 89 | 2014 |
| An intact microbiota is required for the gastrointestinal toxicity of the immunosuppressant mycophenolate mofetil KL Flannigan, MR Taylor, SK Pereira, J Rodriguez-Arguello, AW Moffat, ... The Journal of Heart and Lung Transplantation 37 (9), 1047-1059, 2018 | 85 | 2018 |
| The reverse mode of the Na+/Ca2+ exchanger provides a source of Ca2+ for store refilling following agonist-induced Ca2+ mobilization S Hirota, E Pertens, LJ Janssen American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (2 …, 2007 | 85 | 2007 |
| Pregnane X receptor activation attenuates inflammation-associated intestinal epithelial barrier dysfunction by inhibiting cytokine-induced myosin light-chain kinase expression … A Garg, A Zhao, SL Erickson, S Mukherjee, AJ Lau, L Alston, TKH Chang, ... Journal of Pharmacology and Experimental Therapeutics 359 (1), 91-101, 2016 | 78 | 2016 |
Paul L. BeckProfessor Medicine, Division of Gastroenterology, University of Calgary.Verified email at ucalgary.ca
