Predicting adverse side effects of drugs LC Huang, X Wu, JY Chen BMC genomics 12, 1-10, 2011 | 161 | 2011 |
Prediction of human population responses to toxic compounds by a collaborative competition F Eduati, LM Mangravite, T Wang, H Tang, JC Bare, R Huang, T Norman, ... Nature biotechnology 33 (9), 933-940, 2015 | 121 | 2015 |
PDBe-KB: a community-driven resource for structural and functional annotations M Varadi, J Berrisford, M Deshpande, SS Nair, A Gutmanas, D Armstrong, ... Nucleic Acids Research 48 (D1), D344-D353, 2020 | 84 | 2020 |
Deep evolutionary analysis reveals the design principles of fold A glycosyltransferases R Taujale, A Venkat, LC Huang, Z Zhou, W Yeung, KM Rasheed, S Li, ... elife 9, e54532, 2020 | 83 | 2020 |
Predicting adverse drug reaction profiles by integrating protein interaction networks with drug structures LC Huang, X Wu, JY Chen Proteomics 13 (2), 313-324, 2013 | 70 | 2013 |
Classification of cancer primary sites using machine learning and somatic mutations Y Chen, J Sun, LC Huang, H Xu, Z Zhao BioMed research international 2015 (1), 491502, 2015 | 49 | 2015 |
Integrative annotation and knowledge discovery of kinase post-translational modifications and cancer-associated mutations through federated protein ontologies and resources LC Huang, KE Ross, TR Baffi, H Drabkin, KJ Kochut, Z Ruan, ... Scientific reports 8 (1), 6518, 2018 | 35 | 2018 |
A resource for exploring the understudied human kinome for research and therapeutic opportunities N Moret, C Liu, BM Gyori, JA Bachman, A Steppi, C Hug, R Taujale, ... BioRxiv, 2020.04. 02.022277, 2020 | 29 | 2020 |
AutoCriteria: a generalizable clinical trial eligibility criteria extraction system powered by large language models S Datta, K Lee, H Paek, FJ Manion, N Ofoegbu, J Du, Y Li, LC Huang, ... Journal of the American Medical Informatics Association 31 (2), 375-385, 2024 | 27 | 2024 |
Extracting genetic alteration information for personalized cancer therapy from ClinicalTrials. gov J Xu, HJ Lee, J Zeng, Y Wu, Y Zhang, LC Huang, A Johnson, V Holla, ... Journal of the American Medical Informatics Association 23 (4), 750-757, 2016 | 24 | 2016 |
KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases LC Huang, R Taujale, N Gravel, A Venkat, W Yeung, DP Byrne, PA Eyers, ... BMC bioinformatics 22, 1-25, 2021 | 16 | 2021 |
Network‐Assisted Prediction of Potential Drugs for Addiction J Sun, LC Huang, H Xu, Z Zhao BioMed research international 2014 (1), 258784, 2014 | 15 | 2014 |
Quantitative Structure–Mutation–Activity Relationship Tests (QSMART) model for protein kinase inhibitor response prediction LC Huang, W Yeung, Y Wang, H Cheng, A Venkat, S Li, P Ma, K Rasheed, ... BMC bioinformatics 21, 1-22, 2020 | 12 | 2020 |
A weighted and integrated drug-target interactome: drug repurposing for schizophrenia as a use case LC Huang, E Soysal, WJ Zheng, Z Zhao, H Xu, J Sun BMC Systems Biology 9, 1-13, 2015 | 11 | 2015 |
Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition CA Pilo, TR Baffi, AP Kornev, MT Kunkel, M Malfavon, DH Chen, ... Science Signaling, 2022 | 8* | 2022 |
Dark kinase annotation, mining, and visualization using the Protein Kinase Ontology S Soleymani, N Gravel, LC Huang, W Yeung, E Bozorgi, NG Bendzunas, ... PeerJ 11, e16087, 2023 | 7 | 2023 |
SEETrials: Leveraging Large Language Models for Safety and Efficacy Extraction in Oncology Clinical Trials K Lee, H Paek, LC Huang, CB Hilton, S Datta, J Higashi, N Ofoegbu, ... medRxiv, 2024.01. 18.24301502, 2024 | 6 | 2024 |
Ensemble pretrained language models to extract biomedical knowledge from literature Z Li, Q Wei, LC Huang, J Li, Y Hu, YS Chuang, J He, A Das, VK Keloth, ... Journal of the American Medical Informatics Association, ocae061, 2024 | 5 | 2024 |
CATTLE (CAncer treatment treasury with linked evidence): An integrated knowledge base for personalized oncology research and practice E Soysal, HJ Lee, Y Zhang, LC Huang, X Chen, Q Wei, W Zheng, ... CPT: Pharmacometrics & Systems Pharmacology 6 (3), 188-196, 2017 | 4 | 2017 |
UTHealth@ BioCreativeVII: domain-specific transformer models for drug-protein relation extraction A Das, Z Li, Q Wei, J Li, LC Huang, Y Hu, R Li, WJ Zheng, H Xu Proceedings of the BioCreative VII challenge evaluation workshop 17, 2021 | 3 | 2021 |