p53 in the DNA-damage-repair process AB Williams, B Schumacher Cold Spring Harbor perspectives in medicine 6 (5), a026070, 2016 | 884 | 2016 |
The central role of DNA damage in the ageing process B Schumacher, J Pothof, J Vijg, JHJ Hoeijmakers Nature 592 (7856), 695-703, 2021 | 636 | 2021 |
The p53 network: cellular and systemic DNA damage responses in aging and cancer HC Reinhardt, B Schumacher Trends in Genetics 28 (3), 128-136, 2012 | 578 | 2012 |
DNA repair mechanisms in cancer development and therapy A Torgovnick, B Schumacher Frontiers in genetics 6, 157, 2015 | 480 | 2015 |
The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis B Schumacher, K Hofmann, S Boulton, A Gartner Current biology 11 (21), 1722-1727, 2001 | 447 | 2001 |
DNA damage responses and p53 in the aging process HL Ou, B Schumacher Blood, The Journal of the American Society of Hematology 131 (5), 488-495, 2018 | 321 | 2018 |
Age to survive: DNA damage and aging B Schumacher, GA Garinis, JHJ Hoeijmakers Trends in Genetics 24 (2), 77-85, 2008 | 304 | 2008 |
Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis B Schumacher, M Hanazawa, MH Lee, S Nayak, K Volkmann, R Hofmann, ... Cell 120 (3), 357-368, 2005 | 262 | 2005 |
Delayed and accelerated aging share common longevity assurance mechanisms B Schumacher, I Van Der Pluijm, MJ Moorhouse, T Kosteas, AR Robinson, ... PLoS genetics 4 (8), e1000161, 2008 | 258 | 2008 |
Impact of genomic damage and ageing on stem cell function A Behrens, JM Van Deursen, KL Rudolph, B Schumacher Nature cell biology 16 (3), 201-207, 2014 | 251 | 2014 |
DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance MA Ermolaeva, A Segref, A Dakhovnik, HL Ou, JI Schneider, ... Nature 501 (7467), 416-420, 2013 | 233 | 2013 |
Insights from the worm: the C. elegans model for innate immunity MA Ermolaeva, B Schumacher Seminars in immunology 26 (4), 303-309, 2014 | 229 | 2014 |
DNA damage response and immune defense: links and mechanisms R Nakad, B Schumacher Frontiers in genetics 7, 147, 2016 | 225 | 2016 |
C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage B Schumacher, C Schertel, N Wittenburg, S Tuck, S Mitani, A Gartner, ... Cell Death & Differentiation 12 (2), 153-161, 2005 | 221 | 2005 |
Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity B Schwer, B Schumacher, DB Lombard, C Xiao, MV Kurtev, J Gao, ... Proceedings of the National Academy of Sciences 107 (50), 21790-21794, 2010 | 209 | 2010 |
Next generation sequencing of miRNAs–strategies, resources and methods S Motameny, S Wolters, P Nürnberg, B Schumacher Genes 1 (1), 70-84, 2010 | 169 | 2010 |
Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity GA Garinis, LM Uittenboogaard, H Stachelscheid, M Fousteri, ... Nature cell biology 11 (5), 604-615, 2009 | 163 | 2009 |
The p53 network: cellular and systemic DNA damage responses in cancer and aging PL Vaddavalli, B Schumacher Trends in Genetics 38 (6), 598-612, 2022 | 152 | 2022 |
Involvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during development H Lans, JA Marteijn, B Schumacher, JHJ Hoeijmakers, G Jansen, ... PLoS genetics 6 (5), e1000941, 2010 | 150 | 2010 |
Systemic DNA damage responses in aging and diseases F Ribezzo, Y Shiloh, B Schumacher Seminars in cancer biology 37, 26-35, 2016 | 134 | 2016 |