The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases S Krasemann, C Madore, R Cialic, C Baufeld, N Calcagno, R El Fatimy, ... Immunity 47 (3), 566-581. e9, 2017 | 2345 | 2017 |
Brown adipose tissue activity controls triglyceride clearance A Bartelt, OT Bruns, R Reimer, H Hohenberg, H Ittrich, K Peldschus, ... Nature medicine 17 (2), 200-205, 2011 | 1891 | 2011 |
Adipose tissue browning and metabolic health A Bartelt, J Heeren Nature Reviews Endocrinology 10 (1), 24-36, 2014 | 1336 | 2014 |
Next-generation in vivo optical imaging with short-wave infrared quantum dots OT Bruns, TS Bischof, DK Harris, D Franke, Y Shi, L Riedemann, A Bartelt, ... Nature biomedical engineering 1 (4), 0056, 2017 | 623 | 2017 |
The endocrine function of adipose tissues in health and cardiometabolic disease L Scheja, J Heeren Nature reviews endocrinology 15 (9), 507-524, 2019 | 604 | 2019 |
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development JFP Berbée, MR Boon, PPSJ Khedoe, A Bartelt, C Schlein, A Worthmann, ... Nature communications 6 (1), 6356, 2015 | 512 | 2015 |
Metabolic-associated fatty liver disease and lipoprotein metabolism J Heeren, L Scheja Molecular metabolism 50, 101238, 2021 | 428 | 2021 |
Apolipoprotein AV accelerates plasma hydrolysis of triglyceriderich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase M Merkel, B Loeffler, M Kluger, N Fabig, G Geppert, LA Pennacchio, ... Journal of biological chemistry 280 (22), 21553-21560, 2005 | 399 | 2005 |
Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b JW Kornfeld, C Baitzel, AC Könner, HT Nicholls, MC Vogt, K Herrmanns, ... Nature 494 (7435), 111-115, 2013 | 371 | 2013 |
De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health L Eissing, T Scherer, K Tödter, U Knippschild, JW Greve, WA Buurman, ... Nature communications 4 (1), 1528, 2013 | 361 | 2013 |
Sort1, encoded by the cardiovascular risk locus 1p13. 3, is a regulator of hepatic lipoprotein export M Kjolby, OM Andersen, T Breiderhoff, AW Fjorback, KM Pedersen, ... Cell metabolism 12 (3), 213-223, 2010 | 317 | 2010 |
Disturbed cholesterol traffic but normal proteolytic function in LAMP-1/LAMP-2 double-deficient fibroblasts EL Eskelinen, CK Schmidt, S Neu, M Willenborg, G Fuertes, N Salvador, ... Molecular biology of the cell 15 (7), 3132-3145, 2004 | 317 | 2004 |
The TMAO-producing enzyme flavin-containing monooxygenase 3 regulates obesity and the beiging of white adipose tissue RC Schugar, DM Shih, M Warrier, RN Helsley, A Burrows, D Ferguson, ... Cell reports 19 (12), 2451-2461, 2017 | 292 | 2017 |
Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis A Worthmann, C John, MC Rühlemann, M Baguhl, FA Heinsen, ... Nature medicine 23 (7), 839-849, 2017 | 289 | 2017 |
FGF21 lowers plasma triglycerides by accelerating lipoprotein catabolism in white and brown adipose tissues C Schlein, S Talukdar, M Heine, AW Fischer, LM Krott, SK Nilsson, ... Cell metabolism 23 (3), 441-453, 2016 | 277 | 2016 |
TGF-β-dependent induction of CD4+ CD25+ Foxp3+ Tregs by liver sinusoidal endothelial cells A Carambia, B Freund, D Schwinge, M Heine, A Laschtowitz, S Huber, ... Journal of hepatology 61 (3), 594-599, 2014 | 269 | 2014 |
Nanoparticle-based autoantigen delivery to Treg-inducing liver sinusoidal endothelial cells enables control of autoimmunity in mice A Carambia, B Freund, D Schwinge, OT Bruns, SC Salmen, H Ittrich, ... Journal of hepatology 62 (6), 1349-1356, 2015 | 189 | 2015 |
Real-time magnetic resonance imaging and quantification of lipoprotein metabolism in vivo using nanocrystals OT Bruns, H Ittrich, K Peldschus, MG Kaul, UI Tromsdorf, J Lauterwasser, ... Nature nanotechnology 4 (3), 193-201, 2009 | 189 | 2009 |
Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism N Oehler, T Volz, OD Bhadra, J Kah, L Allweiss, K Giersch, J Bierwolf, ... Hepatology 60 (5), 1483-1493, 2014 | 185 | 2014 |
Metabolic interplay between white, beige, brown adipocytes and the liver L Scheja, J Heeren Journal of hepatology 64 (5), 1176-1186, 2016 | 179 | 2016 |