The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells J MENENDEZ, J Joven, S Cufí, B Corominas-Faja, C Oliveras-Ferraros, ... Cell cycle 12 (8), 1166-1179, 2013 | 186 | 2013 |
The anti-malarial chloroquine overcomes primary resistance and restores sensitivity to trastuzumab in HER2-positive breast cancer S Cufí, A Vazquez-Martin, C Oliveras-Ferraros, B Corominas-Faja, ... Scientific reports 3 (1), 2469, 2013 | 146 | 2013 |
Cell cycle regulation by the nutrient-sensing mammalian target of rapamycin (mTOR) pathway E Cuyàs, B Corominas-Faja, J Joven, JA Menendez Cell Cycle Control: Mechanisms and Protocols, 113-144, 2014 | 139 | 2014 |
Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity S Verdura, E Cuyàs, E Cortada, J Brunet, E Lopez-Bonet, ... Aging (Albany NY) 12 (1), 8, 2020 | 134 | 2020 |
Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response F Fonseca, R de la Torre, L Díaz, A Pastor, E Cuyàs, N Pizarro, ... PloS one 6 (5), e19527, 2011 | 125 | 2011 |
Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells B Corominas-Faja, E Cuyàs, J Gumuzio, J Bosch-Barrera, O Leis, ... Oncotarget 5 (18), 8306, 2014 | 124 | 2014 |
Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway B Corominas-Faja, S Cufí, C Oliveras-Ferraros, E Cuyàs, E López-Bonet, ... Cell cycle 12 (18), 3109-3124, 2013 | 121 | 2013 |
Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism E Cuyàs, S Fernández-Arroyo, S Verdura, RÁF García, J Stursa, L Werner, ... Oncogene 37 (7), 963-970, 2018 | 117 | 2018 |
Metformin is a direct SIRT1-activating compound: computational modeling and experimental validation E Cuyàs, S Verdura, L Llorach-Parés, S Fernández-Arroyo, J Joven, ... Frontiers in endocrinology 9, 657, 2018 | 115 | 2018 |
Perfectionism dimensions in major postpartum depression E Gelabert, S Subirà, L García-Esteve, P Navarro, A Plaza, E Cuyàs, ... Journal of affective disorders 136 (1-2), 17-25, 2012 | 100 | 2012 |
Stem cell-like ALDHbright cellular states in EGFR-mutant non-small cell lung cancer: A novel mechanism of acquired resistance to erlotinib targetable with the … B Corominas-Faja, C Oliveras-Ferraros, E Cuyas, A Segura-Carretero, ... Cell cycle 12 (21), 3390-3404, 2013 | 99 | 2013 |
IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations A Vazquez-Martin, S Cufí, C Oliveras-Ferraros, VZ Torres-Garcia, ... Scientific reports 3 (1), 1-15, 2013 | 98 | 2013 |
Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate A Vazquez-Martin, C Van den Haute, S Cufí, B Corominas-Faja, E Cuyàs, ... Aging (Albany NY) 8 (7), 1330, 2016 | 93 | 2016 |
Metformin as an archetype immuno-metabolic adjuvant for cancer immunotherapy S Verdura, E Cuyàs, B Martin-Castillo, JA Menendez Oncoimmunology 8 (10), e1633235, 2019 | 92 | 2019 |
Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer B Corominas-Faja, L Vellon, E Cuyàs, M Buxó, B Martin-Castillo, D Serra, ... Histology and histopathology 32 (7), 687, 2016 | 81 | 2016 |
Silibinin meglumine, a water-soluble form of milk thistle silymarin, is an orally active anti-cancer agent that impedes the epithelial-to-mesenchymal transition (EMT) in EGFR … S Cufí, R Bonavia, A Vazquez-Martin, B Corominas-Faja, ... Food and chemical toxicology 60, 360-368, 2013 | 79 | 2013 |
The consequences of 3, 4-methylenedioxymethamphetamine induced CYP2D6 inhibition in humans B O'Mathúna, M Farré, A Rostami-Hodjegan, J Yang, E Cuyàs, M Torrens, ... Journal of clinical psychopharmacology 28 (5), 523-529, 2008 | 78 | 2008 |
Metformin directly targets the H3K27me3 demethylase KDM6A/UTX E Cuyas, S Verdura, L Llorach‐Pares, S Fernández‐Arroyo, ... Aging cell 17 (4), e12772, 2018 | 77 | 2018 |
Silibinin is a direct inhibitor of STAT3 S Verdura, E Cuyàs, L Llorach-Parés, A Pérez-Sánchez, V Micol, ... Food and Chemical Toxicology 116, 161-172, 2018 | 77 | 2018 |
Silibinin suppresses EMT-driven erlotinib resistance by reversing the high miR-21/low miR-200c signature in vivo S Cufí, R Bonavia, A Vazquez-Martin, C Oliveras-Ferraros, ... Scientific reports 3 (1), 2459, 2013 | 77 | 2013 |