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Xingcheng Chen
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The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression
C He, D Mao, G Hua, X Lv, X Chen, PC Angeletti, J Dong, SW Remmenga, ...
EMBO molecular medicine 7 (11), 1426-1449, 2015
2972015
The hippo pathway effector YAP regulates motility, invasion, and castration-resistant growth of prostate cancer cells
L Zhang, S Yang, X Chen, S Stauffer, F Yu, SM Lele, K Fu, K Datta, ...
Molecular and cellular biology 35 (8), 1350-1362, 2015
1772015
Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3
S Yang, L Zhang, V Purohit, SK Shukla, X Chen, F Yu, K Fu, Y Chen, ...
Oncotarget 6 (34), 36019, 2015
1072015
Timely expression and activation of YAP1 in granulosa cells is essential for ovarian follicle development
X Lv, C He, C Huang, H Wang, G Hua, Z Wang, J Zhou, X Chen, B Ma, ...
The FASEB Journal 33 (9), 10049, 2019
1012019
A human papillomavirus-independent cervical cancer animal model reveals unconventional mechanisms of cervical carcinogenesis
C He, X Lv, C Huang, PC Angeletti, G Hua, J Dong, J Zhou, Z Wang, B Ma, ...
Cell reports 26 (10), 2636-2650. e5, 2019
692019
YAP 1‐LATS 2 feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis
C He, X Lv, C Huang, G Hua, B Ma, X Chen, PC Angeletti, J Dong, J Zhou, ...
EMBO reports 20 (3), e44948, 2019
602019
Ajuba phosphorylation by CDK1 promotes cell proliferation and tumorigenesis
X Chen, S Stauffer, Y Chen, J Dong
Journal of Biological Chemistry 291 (28), 14761-14772, 2016
562016
Zyxin promotes colon cancer tumorigenesis in a mitotic phosphorylation-dependent manner and through CDK8-mediated YAP activation
J Zhou, Y Zeng, L Cui, X Chen, S Stauffer, Z Wang, F Yu, SM Lele, ...
Proceedings of the National Academy of Sciences 115 (29), E6760-E6769, 2018
542018
CDK1 phosphorylation of TAZ in mitosis inhibits its oncogenic activity
L Zhang, X Chen, S Stauffer, S Yang, Y Chen, J Dong
Oncotarget 6 (31), 31399, 2015
392015
Oncoprotein YAP regulates the spindle checkpoint activation in a mitotic phosphorylation-dependent manner through up-regulation of BubR1
S Yang, L Zhang, X Chen, Y Chen, J Dong
Journal of Biological Chemistry 290 (10), 6191-6202, 2015
392015
CDK1-mediated mitotic phosphorylation of PBK is involved in cytokinesis and inhibits its oncogenic activity
S Stauffer, Y Zeng, J Zhou, X Chen, Y Chen, J Dong
Cellular signalling 39, 74-83, 2017
372017
KIBRA promotes prostate cancer cell proliferation and motility
S Stauffer, X Chen, L Zhang, Y Chen, J Dong
The FEBS journal 283 (10), 1800-1811, 2016
332016
Cyclin-dependent kinase 1 (CDK1)-mediated mitotic phosphorylation of the transcriptional co-repressor Vgll4 inhibits its tumor-suppressing activity
Y Zeng, S Stauffer, J Zhou, X Chen, Y Chen, J Dong
Journal of Biological Chemistry 292 (36), 15028-15038, 2017
252017
Reprogramming of ovarian granulosa cells by YAP1 leads to development of high-grade cancer with mesenchymal lineage and serous features
X Lv, C He, C Huang, G Hua, X Chen, BK Timm, VM Maclin, AA Haggerty, ...
Science bulletin 65 (15), 1281-1296, 2020
172020
Cyclin-dependent kinase 1-mediated phosphorylation of YES links mitotic arrest and apoptosis during antitubulin chemotherapy
Z Wang, X Chen, MZ Zhong, S Yang, J Zhou, DL Klinkebiel, AR Karpf, ...
Cellular signalling 52, 137-146, 2018
132018
MST2 phosphorylation at serine 385 in mitosis inhibits its tumor suppressing activity
X Chen, Y Chen, J Dong
Cellular signalling 28 (12), 1826-1832, 2016
102016
Regulation of Canonical and Non-Canonical Hippo Pathway Components in Mitosis and Cancer
S Stauffer
2018
Role of zyxin in mitosis and colon cancer
J Zhou, J Dong, Y Chen, X Chen, S Stauffer, Y Zeng
Cancer Research 77 (13_Supplement), 3458-3458, 2017
2017
Regulation of AMP‐Activated Protein Kinase by Cyclin‐Dependent Kinase 1 in Mitosis
SD Stauffer, X Chen, Y Chen, J Dong
The FASEB Journal 30, 638.2-638.2, 2016
2016
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