Synergistic effects of common schizophrenia risk variants N Schrode, SM Ho, K Yamamuro, A Dobbyn, L Huckins, MR Matos, ... Nature genetics 51 (10), 1475-1485, 2019 | 233 | 2019 |
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk P Rajarajan, T Borrman, W Liao, N Schrode, E Flaherty, C Casiño, ... Science 362 (6420), eaat4311, 2018 | 218 | 2018 |
Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells SM Ho, BJ Hartley, TCW Julia, M Beaumont, K Stafford, PA Slesinger, ... Methods 101, 113-124, 2016 | 173 | 2016 |
Dual Functions of Highly Potent Graphene Derivative–Poly-l-Lysine Composites To Inhibit Bacteria and Support Human Cells S Some, SM Ho, P Dua, E Hwang, YH Shin, HJ Yoo, JS Kang, D Lee, ... ACS nano 6 (8), 7151-7161, 2012 | 170 | 2012 |
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain Y Jiang, YHE Loh, P Rajarajan, T Hirayama, W Liao, BS Kassim, ... Nature genetics 49 (8), 1239-1250, 2017 | 160 | 2017 |
Transformative network modeling of multi-omics data reveals detailed circuits, key regulators, and potential therapeutics for Alzheimer’s disease M Wang, A Li, M Sekiya, ND Beckmann, X Quan, N Schrode, ... Neuron 109 (2), 257-272. e14, 2021 | 138 | 2021 |
In utero exposure to maternal smoking is associated with DNA methylation alterations and reduced neuronal content in the developing fetal brain Z Chatterton, BJ Hartley, MH Seok, N Mendelev, S Chen, M Milekic, ... Epigenetics & chromatin 10, 1-11, 2017 | 102 | 2017 |
Evaluating synthetic activation and repression of neuropsychiatric-related genes in hiPSC-derived NPCs, neurons, and astrocytes SM Ho, BJ Hartley, E Flaherty, P Rajarajan, R Abdelaal, I Obiorah, ... Stem cell reports 9 (2), 615-628, 2017 | 83 | 2017 |
Cdo interacts with APPL1 and activates Akt in myoblast differentiation GU Bae, JR Lee, BG Kim, JW Han, YE Leem, HJ Lee, SM Ho, MJ Hahn, ... Molecular biology of the cell 21 (14), 2399-2411, 2010 | 62 | 2010 |
Characterization of molecular and cellular phenotypes associated with a heterozygous CNTNAP2 deletion using patient-derived hiPSC neural cells IS Lee, C Carvalho, P Douvaras, SM Ho, BJ Hartley, LW Zuccherato, ... NPJ schizophrenia 1 (1), 1-5, 2015 | 60 | 2015 |
ASCL1-and DLX2-induced GABAergic neurons from hiPSC-derived NPCs N Barretto, H Zhang, SK Powell, MB Fernando, S Zhang, EK Flaherty, ... Journal of neuroscience methods 334, 108548, 2020 | 45 | 2020 |
Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models J Xu, BJ Hartley, P Kurup, A Phillips, A Topol, M Xu, C Ononenyi, ... Molecular psychiatry 23 (2), 271-281, 2018 | 45 | 2018 |
Cdo suppresses canonical Wnt signalling via interaction with Lrp6 thereby promoting neuronal differentiation MH Jeong, SM Ho, TA Vuong, SB Jo, G Liu, SA Aaronson, YE Leem, ... Nature communications 5 (1), 5455, 2014 | 41 | 2014 |
TGF-β-activated kinase 1 (TAK1) and apoptosis signal-regulating kinase 1 (ASK1) interact with the promyogenic receptor Cdo to promote myogenic differentiation via activation of … P Tran, SM Ho, BG Kim, TA Vuong, YE Leem, GU Bae, JS Kang Journal of Biological Chemistry 287 (15), 11602-11615, 2012 | 40 | 2012 |
Gas1 cooperates with Cdo and promotes myogenic differentiation via activation of p38MAPK YE Leem, JW Han, HJ Lee, HL Ha, YL Kwon, SM Ho, BG Kim, P Tran, ... Cellular signalling 23 (12), 2021-2029, 2011 | 35 | 2011 |
From “directed differentiation” to “neuronal induction”: Modeling neuropsychiatric disease: Supplementary issue: Stem cell biology SM Ho, A Topol, KJ Brennand Biomarker insights 10, BMI. S20066, 2015 | 34 | 2015 |
Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk SK Powell, C O’Shea, K Townsley, I Prytkova, K Dobrindt, R Elahi, ... Molecular psychiatry 28 (5), 1970-1982, 2023 | 24 | 2023 |
Integration of CRISPR-engineering and hiPSC-based models of psychiatric genomics MR Matos, SM Ho, N Schrode, KJ Brennand Molecular and Cellular Neuroscience 107, 103532, 2020 | 13 | 2020 |
Activity-dependent transcriptional program in NGN2+ neurons enriched for genetic risk for brain-related disorders Y Ma, J Bendl, BJ Hartley, JF Fullard, R Abdelaal, SM Ho, R Kosoy, ... Biological Psychiatry 95 (2), 187-198, 2024 | 8 | 2024 |
Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons A Li, S Cartwright, A Yu, SM Ho, N Schrode, PJM Deans, MR Matos, ... STAR protocols 2 (2), 100580, 2021 | 8 | 2021 |