Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein C Balducci, M Beeg, M Stravalaci, A Bastone, A Sclip, E Biasini, L Tapella, ... Proceedings of the National Academy of Sciences 107 (5), 2295-2300, 2010 | 610 | 2010 |
A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis G Di Fede, M Catania, M Morbin, G Rossi, S Suardi, G Mazzoleni, ... Science 323 (5920), 1473-1477, 2009 | 510 | 2009 |
The SIRT1 activator resveratrol protects SK‐N‐BE cells from oxidative stress and against toxicity caused by α‐synuclein or amyloid‐β (1‐42) peptide D Albani, L Polito, S Batelli, S De Mauro, C Fracasso, G Martelli, ... Journal of neurochemistry 110 (5), 1445-1456, 2009 | 298 | 2009 |
Inhibition of LRRK2 kinase activity stimulates macroautophagy C Manzoni, A Mamais, S Dihanich, R Abeti, MPM Soutar, H Plun-Favreau, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (12), 2900-2910, 2013 | 179 | 2013 |
Pathogenic Parkinson’s disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation C Manzoni, A Mamais, S Dihanich, P McGoldrick, MJ Devine, J Zerle, ... Biochemical and biophysical research communications 441 (4), 862-866, 2013 | 102 | 2013 |
LRRK2 and human disease: a complicated question or a question of complexes? PA Lewis, C Manzoni Science Signaling 5 (207), pe2, 2012 | 96 | 2012 |
Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies C Manzoni, PA Lewis The FASEB Journal 27 (9), 3424-3429, 2013 | 80 | 2013 |
Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction C Airoldi, L Colombo, C Manzoni, E Sironi, A Natalello, SM Doglia, ... Organic & biomolecular chemistry 9 (2), 463-472, 2011 | 66 | 2011 |
Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases A Mamais, M Raja, C Manzoni, S Dihanich, A Lees, D Moore, PA Lewis, ... Neurobiology of disease 58, 183-190, 2013 | 61 | 2013 |
Conformational plasticity of the Gerstmann–Sträussler–Scheinker disease peptide as indicated by its multiple aggregation pathways A Natalello, VV Prokorov, F Tagliavini, M Morbin, G Forloni, M Beeg, ... Journal of molecular biology 381 (5), 1349-1361, 2008 | 58 | 2008 |
The molecular assembly of amyloid Aβ controls its neurotoxicity and binding to cellular proteins C Manzoni, L Colombo, P Bigini, V Diana, A Cagnotto, M Messa, M Lupi, ... PloS one 6 (9), e24909, 2011 | 49 | 2011 |
Overcoming synthetic Aβ peptide aging: a new approach to an age-old problem C Manzoni, L Colombo, M Messa, A Cagnotto, L Cantu, E Del Favero, ... Amyloid 16 (2), 71-80, 2009 | 46 | 2009 |
Neurotoxic and gliotrophic activity of a synthetic peptide homologous to Gerstmann–Sträussler–Scheinker disease amyloid protein L Fioriti, N Angeretti, L Colombo, A De Luigi, A Colombo, C Manzoni, ... The Journal of neuroscience 27 (7), 1576-1583, 2007 | 46 | 2007 |
Gerstmann-Sträussler-Scheinker disease amyloid protein polymerizes according to the “dock-and-lock” model M Gobbi, L Colombo, M Morbin, G Mazzoleni, E Accardo, M Vanoni, ... Journal of Biological Chemistry 281 (2), 843-849, 2006 | 43 | 2006 |
Correction: Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue. MJ Devine, A Kaganovich, M Ryten, A Mamais, D Trabzuni, C Manzoni, ... PloS one 7 (1), 2012 | 38* | 2012 |
Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue MJ Devine, A Kaganovich, M Ryten, A Mamais, D Trabzuni, C Manzoni, ... PloS one 6 (7), e22489, 2011 | 38 | 2011 |
LRRK2 and autophagy: a common pathway for disease. C Manzoni Biochemical Society Transactions 40 (5), 2012 | 29 | 2012 |
Acetylcholinesterase triggers the aggregation of PrP 106–126 M Pera, S Roman, M Ratia, P Camps, D Munoz-Torrero, L Colombo, ... Biochemical and biophysical research communications 346 (1), 89-94, 2006 | 29 | 2006 |
Rare variants in LRRK1 and Parkinson's disease EC Schulte, DC Ellwanger, S Dihanich, C Manzoni, K Stangl, B Schormair, ... neurogenetics, 1-9, 2013 | 28 | 2013 |
GTP binding controls complex formation by the human ROCO protein MASL1 S Dihanich, L Civiero, C Manzoni, A Mamais, R Bandopadhyay, ... FEBS Journal 281 (1), 261-274, 2014 | 16 | 2014 |