Nitric oxide‐induced mitochondrial fission is regulated by dynamin‐related GTPases in neurons MJ Barsoum, H Yuan, AA Gerencser, G Liot, Y Kushnareva, S Gräber, ... The EMBO journal 25 (16), 3900-3911, 2006 | 773 | 2006 |
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity W Song, J Chen, A Petrilli, G Liot, E Klinglmayr, Y Zhou, P Poquiz, J Tjong, ... Nature medicine 17 (3), 377, 2011 | 604 | 2011 |
Vesicular glycolysis provides on-board energy for fast axonal transport D Zala, MV Hinckelmann, H Yu, MML da Cunha, G Liot, FP Cordelières, ... Cell 152 (3), 479-491, 2013 | 518 | 2013 |
Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons E Colin, D Zala, G Liot, H Rangone, M Borrell‐Pagès, XJ Li, F Saudou, ... The EMBO journal 27 (15), 2124-2134, 2008 | 435 | 2008 |
Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA-and ROS-dependent pathway G Liot, B Bossy, S Lubitz, Y Kushnareva, N Sejbuk, E Bossy-Wetzel Cell death and differentiation 16 (6), 899, 2009 | 292 | 2009 |
Local cholesterol increase triggers amyloid precursor protein-Bace1 clustering in lipid rafts and rapid endocytosis C Marquer, V Devauges, JC Cossec, G Liot, S Lécart, F Saudou, ... The FASEB journal 25 (4), 1295-1305, 2011 | 217 | 2011 |
Mutant Huntingtin alters retrograde transport of TrkB receptors in striatal dendrites G Liot, D Zala, P Pla, G Mottet, M Piel, F Saudou Journal of Neuroscience 33 (15), 6298-6309, 2013 | 202 | 2013 |
Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons D Zala, E Colin, H Rangone, G Liot, S Humbert, F Saudou Human molecular genetics 17 (24), 3837-3846, 2008 | 198 | 2008 |
Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease G Keryer, JR Pineda, G Liot, J Kim, P Dietrich, C Benstaali, K Smith, ... The Journal of clinical investigation 121 (11), 4372-4382, 2011 | 190 | 2011 |
Transforming growth factor-β1 potentiates amyloid-β generation in astrocytes and in transgenic mice S Lesné, F Docagne, C Gabriel, G Liot, DK Lahiri, L Buée, L Plawinski, ... Journal of Biological Chemistry 278 (20), 18408-18418, 2003 | 171 | 2003 |
Mitochondrial fission is an upstream and required event for bax foci formation in response to nitric oxide in cortical neurons H Yuan, AA Gerencser, G Liot, SA Lipton, M Ellisman, GA Perkins, ... Cell death and differentiation 14 (3), 462, 2007 | 155 | 2007 |
Angiopoietin-1-induced PI3-kinase activation prevents neuronal apoptosis S Valable, A Bellail, S Lesne, G Liot, ET Mackenzie, D Vivien, ... The FASEB journal 17 (3), 443-445, 2003 | 143 | 2003 |
Tissue plasminogen activator prevents white matter damage following stroke F Correa, M Gauberti, J Parcq, R Macrez, Y Hommet, P Obiang, ... Journal of Experimental Medicine 208 (6), 1229-1242, 2011 | 97 | 2011 |
The brain-specific tissue-type plasminogen activator inhibitor, neuroserpin, protects neurons against excitotoxicity both in vitro and in vivo N Lebeurrier, G Liot, JP Lopez-Atalaya, C Orset, M Fernandez-Monreal, ... Molecular and Cellular Neuroscience 30 (4), 552-558, 2005 | 88 | 2005 |
Tissue‐type plasminogen activator rescues neurones from serum deprivation‐induced apoptosis through a mechanism independent of its proteolytic activity G Liot, BD Roussel, N Lebeurrier, K Benchenane, JP López‐Atalaya, ... Journal of neurochemistry 98 (5), 1458-1464, 2006 | 85 | 2006 |
Energy defects in Huntington's disease: Why “in vivo” evidence matters G Liot, J Valette, J Pépin, J Flament, E Brouillet Biochemical and biophysical research communications 483 (4), 1084-1095, 2017 | 73 | 2017 |
Neurotrophin-3-induced PI-3 kinase/Akt signaling rescues cortical neurons from apoptosis G Liot, C Gabriel, M Cacquevel, C Ali, ET MacKenzie, A Buisson, D Vivien Experimental neurology 187 (1), 38-46, 2004 | 63 | 2004 |
The mTOR inhibitor Everolimus synergizes with the PI3K inhibitor GDC0941 to enhance anti-tumor efficacy in uveal melanoma N Amirouchene-Angelozzi, E Frisch-Dit-Leitz, G Carita, A Dahmani, ... Oncotarget 7 (17), 23633, 2016 | 55 | 2016 |
Transforming Growth Factor-β1—Modulated Cerebral Gene Expression S Lesné, S Blanchet, F Docagne, G Liot, L Plawinski, ET MacKenzie, ... Journal of Cerebral Blood Flow & Metabolism 22 (9), 1114-1123, 2002 | 36 | 2002 |
Sulfheme formation during homocysteine S-oxygenation by catalase in cancers and neurodegenerative diseases D Padovani, A Hessani, FT Castillo, G Liot, M Andriamihaja, A Lan, ... Nature communications 7, 13386, 2016 | 34 | 2016 |