| A22 disrupts the bacterial actin cytoskeleton by directly binding and inducing a low-affinity state in MreB GJ Bean, ST Flickinger, WM Westler, ME McCully, D Sept, DB Weibel, ... Biochemistry 48 (22), 4852-4857, 2009 | 196 | 2009 |
| Structure/Function Analysis of the Interaction of Phosphatidylinositol 4, 5-Bisphosphate with Actin-capping Protein K Kim, ME McCully, N Bhattacharya, B Butler, D Sept, JA Cooper Journal of Biological Chemistry 282 (8), 5871, 2007 | 99 | 2007 |
| Microscopic Reversibility of Protein Folding in Molecular Dynamics Simulations of the Engrailed Homeodomain ME McCully, DAC Beck, V Daggett Biochemistry 47 (27), 7079-7089, 2008 | 67 | 2008 |
| Structural and Functional Consequences of the Cardiac Troponin C L48Q Ca2+-Sensitizing Mutation D Wang, IM Robertson, MX Li, ME McCully, ML Crane, Z Luo, AY Tu, ... Biochemistry 51 (22), 4473-4487, 2012 | 59 | 2012 |
| The denatured state dictates the topology of two proteins with almost identical sequence but different native structure and function A Morrone, ME McCully, PN Bryan, M Brunori, V Daggett, S Gianni, ... Journal of Biological Chemistry 286 (5), 3863-3872, 2011 | 52 | 2011 |
| Structural and Functional Consequences of Cardiac Troponin C L57Q and I61Q Ca2+-Desensitizing Variants D Wang, ME McCully, Z Luo, J McMichael, AY Tu, V Daggett, M Regnier Archives of biochemistry and biophysics, 2013 | 39 | 2013 |
| Refolding the engrailed homeodomain: structural basis for the accumulation of a folding intermediate ME McCully, DAC Beck, AR Fersht, V Daggett Biophysical journal 99 (5), 1628-1636, 2010 | 29 | 2010 |
| The stability and dynamics of computationally designed proteins NA Gonzalez, BA Li, ME McCully Protein Engineering, Design and Selection 35, gzac001, 2022 | 26 | 2022 |
| Multimolecule test-tube simulations of protein unfolding and aggregation ME McCully, DAC Beck, V Daggett Proceedings of the National Academy of Sciences 109 (44), 17851-17856, 2012 | 20 | 2012 |
| A dynamic hydrophobic core and surface salt bridges thermostabilize a designed three-helix bundle C Nguyen, JT Young, GG Slade, RJ Oliveira, ME McCully Biophysical Journal 116 (4), 621-632, 2019 | 19 | 2019 |
| Promiscuous contacts and heightened dynamics increase thermostability in an engineered variant of the engrailed homeodomain ME McCully, DAC Beck, V Daggett Protein Engineering, Design & Selection 26 (1), 35-45, 2013 | 14 | 2013 |
| Molecular dynamics simulations suggest stabilizing mutations in a de novo designed α/β protein M Gill, ME McCully Protein Engineering, Design and Selection 32 (7), 317-329, 2019 | 11 | 2019 |
| The role of electrostatics and folding kinetics on the thermostability of homologous cold shock proteins PHB Ferreira, FC Freitas, ME McCully, GG Slade, RJ de Oliveira Journal of chemical information and modeling 60 (2), 546-561, 2020 | 9 | 2020 |
| Thermostabilization mechanisms in thermophilic versus mesophilic three‐helix bundle proteins C Nguyen, LM Yearwood, ME McCully Journal of computational chemistry 43 (3), 197-205, 2022 | 5 | 2022 |
| A carboxylate to amide substitution that switches protein folds S Gianni, ME McCully, F Malagrinò, D Bonetti, A De Simone, M Brunori, ... Angewandte Chemie 130 (39), 12977-12980, 2018 | 5 | 2018 |
| Mutations that Alter cTnC Ca2+ Binding Affect Interactions with cTnI and Cardiomyocyte Contraction D Wang, FS Korte, J McMichael, CZX Luo, A Tu, ME McCully, V Daggett, ... Biophysical Journal 100 (3), 360a, 2011 | 2 | 2011 |
| Effects of Cardiac TnC Variants on cTnC-cTnI Interaction; Solution and Molecular Dynamics Simulation Studies D Wang, ME McCully, Z Luo, A Tu, V Daggett, M Regnier Biophysical Journal 98 (3), 149a-150a, 2010 | 1 | 2010 |
| Dynamics of the SARS-CoV-2 main protease binding site AS Harith, S Mallalieu, AA Fuller, ME McCully Biophysical Journal 122 (3), 39a, 2023 | | 2023 |
| Thermostability and DNA-Binding Function of Engineered, Chimeric Proteins J DeSanctis, N Boardman, A Persson, M McCully PROTEIN SCIENCE 32, 2023 | | 2023 |
| Editorial overview: Theory and simulation: Molecular modeling from atoms to complexes Q Cui, ME McCully Current opinion in structural biology 73, 102347, 2022 | | 2022 |
Valerie D. DaggettProfessor of Bioengineering, University of WashingtonVerified email at uw.edu
