Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction LW Koblan, JL Doman, C Wilson, JM Levy, T Tay, GA Newby, JP Maianti, ... Nature biotechnology 36 (9), 843-846, 2018 | 920 | 2018 |
Chromatin potential identified by shared single-cell profiling of RNA and chromatin S Ma, B Zhang, LM LaFave, AS Earl, Z Chiang, Y Hu, J Ding, A Brack, ... Cell 183 (4), 1103-1116. e20, 2020 | 837 | 2020 |
Direct cytosolic delivery of CRISPR/Cas9-ribonucleoprotein for efficient gene editing R Mout, M Ray, G Yesilbag Tonga, YW Lee, T Tay, K Sasaki, VM Rotello ACS nano 11 (3), 2452-2458, 2017 | 545 | 2017 |
General Strategy for Direct Cytosolic Protein Delivery via Protein–Nanoparticle Co-engineering R Mout, M Ray, T Tay, K Sasaki, G Yesilbag Tonga, VM Rotello ACS nano 11 (6), 6416-6421, 2017 | 213 | 2017 |
A transcription factor atlas of directed differentiation J Joung, S Ma, T Tay, KR Geiger-Schuller, PC Kirchgatterer, VK Verdine, ... Cell 186 (1), 209-229. e26, 2023 | 126 | 2023 |
In vivo editing of macrophages through systemic delivery of CRISPR‐Cas9‐ribonucleoprotein‐nanoparticle nanoassemblies YW Lee, R Mout, DC Luther, Y Liu, L Castellanos‐García, AS Burnside, ... Advanced therapeutics 2 (10), 1900041, 2019 | 46 | 2019 |
Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements Y Hu, S Ma, VK Kartha, FM Duarte, M Horlbeck, R Zhang, R Shrestha, ... bioRxiv, 2023 | 15 | 2023 |
Direct cytosolic delivery of CRISPR/Cas9-ribonucleoprotein for efficient gene editing T Tay, K Sasaki, VM Rotello ACS nano 11, 2017 | 12 | 2017 |
Cell of origin epigenetic priming determines susceptibility to Tet2 mutation G Schiroli, V Kartha, FM Duarte, TA Kristiansen, C Mayerhofer, ... Nature Communications 15 (1), 4325, 2024 | 2 | 2024 |
Efficient gene editing through direct cytosolic delivery of CRISPR/Cas9-ribonucleoprotein R Mout, M Ray, GY Tonga, YW Lee, T Tay, K Sasaki, VM Rotello ACS nano 11 (3), 2452, 2017 | 2 | 2017 |
Multiscale footprints reveal the organization of cis-regulatory elements Y Hu, MA Horlbeck, R Zhang, S Ma, R Shrestha, VK Kartha, FM Duarte, ... Nature, 1-8, 2025 | | 2025 |
Degradation of IKZF1 prevents epigenetic progression of T cell exhaustion in an antigen-specific assay T Tay, G Bommakanti, E Jaensch, A Gorthi, IK Reddy, Y Hu, R Zhang, ... Cell Reports Medicine 5 (11), 2024 | | 2024 |
Engineering the Epigenetic Regulatory Networks of T Cell Exhaustion and Embryonic Stem Cell Differentiation with Transcription Factor Perturbations T Tay | | 2024 |
Degradation of IKAROS prevents epigenetic progression of T cell exhaustion in a novel antigen-specific assay T Tay, G Bommakanti, E Jaensch, A Gorthi, IK Reddy, Y Hu, R Zhang, ... bioRxiv, 2024.02. 22.581548, 2024 | | 2024 |
Highly Efficient in vivo Editing of Macrophages through Systemic Delivery of CRISPR-Cas9-Ribonucleoprotein-Nanoparticle Nanoassemblies YW Lee, R Mout, DC Luther, Y Liu, L Castellanos-García, AS Burnside, ... | | |