| The fate of plasmid DNA after intravenous injection in mice: involvement of scavenger receptors in its hepatic uptake K Kawabata, Y Takakura, M Hashida Pharmaceutical research 12, 825-830, 1995 | 653 | 1995 |
| In vitro cytotoxicity of macromolecules in different cell culture systems S Choksakulnimitr, S Masuda, H Tokuda, Y Takakura, M Hashida Journal of Controlled Release 34 (3), 233-241, 1995 | 425 | 1995 |
| The 4F2hc/LAT1 complex transports L-DOPA across the blood–brain barrier T Kageyama, M Nakamura, A Matsuo, Y Yamasaki, Y Takakura, ... Brain research 879 (1-2), 115-121, 2000 | 366 | 2000 |
| Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase) M Matsuki, F Yamashita, A Ishida-Yamamoto, K Yamada, C Kinoshita, ... Proceedings of the National Academy of Sciences 95 (3), 1044-1049, 1998 | 365 | 1998 |
| Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes S Kawakami, A Sato, M Nishikawa, F Yamashita, M Hashida Gene therapy 7 (4), 292-299, 2000 | 328 | 2000 |
| Luminescent proteins for high-speed single-cell and whole-body imaging K Saito, YF Chang, K Horikawa, N Hatsugai, Y Higuchi, M Hashida, ... Nature communications 3 (1), 1262, 2012 | 322 | 2012 |
| Macromolecular carrier systems for targeted drug delivery: pharmacokinetic considerations on biodistribution Y Takakura, M Hashida Pharmaceutical research 13, 820-831, 1996 | 310 | 1996 |
| Disposition characteristics of macromolecules in tumor-bearing mice Y Takakura, T Fujita, M Hashida, H Sezaki Pharmaceutical research 7, 339-346, 1990 | 298 | 1990 |
| In silico approaches for predicting ADME properties of drugs F Yamashita, M Hashida Drug metabolism and pharmacokinetics 19 (5), 327-338, 2004 | 256 | 2004 |
| Cell-specific delivery of genes with glycosylated carriers M Hashida, M Nishikawa, F Yamashita, Y Takakura Advanced Drug Delivery Reviews 52 (3), 187-196, 2001 | 256 | 2001 |
| Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting T Terada, M Iwai, S Kawakami, F Yamashita, M Hashida Journal of controlled release 111 (3), 333-342, 2006 | 244 | 2006 |
| Catalase delivery for inhibiting ROS-mediated tissue injury and tumor metastasis M Nishikawa, M Hashida, Y Takakura Advanced drug delivery reviews 61 (4), 319-326, 2009 | 243 | 2009 |
| Lipid carrier systems for targeted drug and gene delivery M Hashida, S Kawakami, F Yamashita Chemical and pharmaceutical bulletin 53 (8), 871-880, 2005 | 243 | 2005 |
| Specific delivery of mitomycin c to the liver, spleen and lung: Nano-and m1crospherical carriers of gelatin Y Toshio, H Mitsuru, M Shozo, S Hitoshi International Journal of Pharmaceutics 8 (2), 131-141, 1981 | 242 | 1981 |
| Disposition and tumor localization of mitomycin C–dextran conjugates in mice Y Takakura, A Takagi, M Hashida, H Sezaki Pharmaceutical research 4, 293-300, 1987 | 241 | 1987 |
| Asialoglycoprotein receptor-mediated gene transfer using novel galactosylated cationic liposomes S Kawakami, F Yamashita, M Nishikawa, Y Takakura, M Hashida Biochemical and biophysical research communications 252 (1), 78-83, 1998 | 225 | 1998 |
| Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and … F Sakurai, R Inoue, Y Nishino, A Okuda, O Matsumoto, T Taga, ... Journal of controlled release 66 (2-3), 255-269, 2000 | 224 | 2000 |
| In vivo gene delivery to the liver using novel galactosylated cationic liposomes S Kawakami, S Fumoto, M Nishikawa, F Yamashita, M Hashida Pharmaceutical Research 17, 306-313, 2000 | 222 | 2000 |
| Hepatocyte-targeted in vivo gene expression by intravenous injection of plasmid DNA complexed with synthetic multi-functional gene delivery system M Nishikawa, M Yamauchi, K Morimoto, E Ishida, Y Takakura, M Hashida Gene therapy 7 (7), 548-555, 2000 | 218 | 2000 |
| Transport of cephalexin to the cerebrospinal fluid directly from the nasal cavity T Sakane, M Akizuki, M Yoshida, S Yamashita, T Nadai, M Hashida, ... Journal of pharmacy and pharmacology 43 (6), 449-451, 1991 | 215 | 1991 |