| Self-assembling cages from coiled-coil peptide modules JM Fletcher, RL Harniman, FRH Barnes, AL Boyle, A Collins, J Mantell, ... Science 340 (6132), 595-599, 2013 | 558 | 2013 |
| Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement D Ugurlar, SC Howes, BJ de Kreuk, RI Koning, RN de Jong, FJ Beurskens, ... Science 359 (6377), 794-797, 2018 | 182 | 2018 |
| Modular design of self-assembling peptide-based nanotubes NC Burgess, TH Sharp, F Thomas, CW Wood, AR Thomson, NR Zaccai, ... Journal of the American Chemical Society 137 (33), 10554-10562, 2015 | 170 | 2015 |
| Insights into IgM-mediated complement activation based on in situ structures of IgM-C1-C4b TH Sharp, AL Boyle, CA Diebolder, A Kros, AJ Koster, P Gros Proceedings of the National Academy of Sciences 116 (24), 11900-11905, 2019 | 169 | 2019 |
| Correlative cryo super-resolution light and electron microscopy on mammalian cells using fluorescent proteins MW Tuijtel, AJ Koster, S Jakobs, FGA Faas, TH Sharp Scientific Reports 9 (1), 1369, 2019 | 140 | 2019 |
| Mucosal reactive oxygen species decrease virulence by disrupting Campylobacter jejuni phosphotyrosine signaling N Corcionivoschi, LAJ Alvarez, TH Sharp, M Strengert, A Alemka, ... Cell host & microbe 12 (1), 47-59, 2012 | 138 | 2012 |
| Anionic lipid nanoparticles preferentially deliver mRNA to the hepatic reticuloendothelial system R Pattipeiluhu, G Arias‐Alpizar, G Basha, KYT Chan, J Bussmann, ... Advanced Materials 34 (16), 2201095, 2022 | 133 | 2022 |
| Squaring the Circle in Peptide Assembly: From Fibers to Discrete Nanostructures by de Novo Design AL Boyle, EHC Bromley, GJ Bartlett, RB Sessions, TH Sharp, CL Williams, ... Journal of the american chemical society 134 (37), 15457-15467, 2012 | 121 | 2012 |
| Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses X Xue, J Wu, D Ricklin, F Forneris, P Di Crescenzio, CQ Schmidt, ... Nature structural & molecular biology 24 (8), 643-651, 2017 | 118 | 2017 |
| Advances in cryo-electron tomography for biology and medicine RI Koning, AJ Koster, TH Sharp Annals of Anatomy-Anatomischer Anzeiger 217, 82-96, 2018 | 111 | 2018 |
| An engineered dimeric protein pore that spans adjacent lipid bilayers S Mantri, K Tanuj Sapra, S Cheley, TH Sharp, H Bayley Nature communications 4 (1), 1725, 2013 | 102 | 2013 |
| Cryo-transmission electron microscopy structure of a gigadalton peptide fiber of de novo design TH Sharp, M Bruning, J Mantell, RB Sessions, AR Thomson, NR Zaccai, ... Proceedings of the National Academy of Sciences 109 (33), 13266-13271, 2012 | 90 | 2012 |
| Heterogeneous MAC initiator and pore structures in a lipid bilayer by phase-plate cryo-electron tomography TH Sharp, AJ Koster, P Gros Cell reports 15 (1), 1-8, 2016 | 84 | 2016 |
| Pharmacological validation of a semi-automated in vitro hippocampal brain slice assay for assessment of seizure liability A Easter, TH Sharp, JP Valentin, CE Pollard Journal of pharmacological and toxicological methods 56 (2), 223-233, 2007 | 60 | 2007 |
| Intracellular membrane traffic at high resolution JRT van Weering, E Brown, TH Sharp, J Mantell, PJ Cullen, P Verkade Methods in cell biology 96, 619-648, 2010 | 57 | 2010 |
| Targeted anion transporter delivery by coiled-coil driven membrane fusion NL Mora, A Bahreman, H Valkenier, H Li, TH Sharp, DN Sheppard, ... Chemical Science 7 (3), 1768-1772, 2016 | 50 | 2016 |
| Squaramide-based supramolecular materials for three-dimensional cell culture of human induced pluripotent stem cells and their derivatives C Tong, T Liu, V Saez Talens, WEM Noteborn, TH Sharp, MMRM Hendrix, ... Biomacromolecules 19 (4), 1091-1099, 2018 | 42 | 2018 |
| Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains L Abendstein, DJ Dijkstra, RTN Tjokrodirijo, PA van Veelen, LA Trouw, ... Nature communications 14 (1), 4027, 2023 | 30 | 2023 |
| PTX3 structure determination using a hybrid cryoelectron microscopy and AlphaFold approach offers insights into ligand binding and complement activation DP Noone, DJ Dijkstra, TT van der Klugt, PA van Veelen, AH de Ru, ... Proceedings of the National Academy of Sciences 119 (33), e2208144119, 2022 | 28 | 2022 |
| Capturing Endocytic Segregation Events with HPF-CLEM E Brown, J van Weering, T Sharp, J Mantell, P Verkade Correlative Light and Electron MIcroscopy, 175, 2012 | 28 | 2012 |
Paul VerkadeProfessor of Bioimaging, University of BristolVerified email at bristol.ac.uk