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Yaru Zhang
Yaru Zhang
Scientist, Amgen
Verified email at caltech.edu
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Year
Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases
L Lauinger, J Li, A Shostak, IA Cemel, N Ha, Y Zhang, PE Merkl, ...
Nature chemical biology 13 (7), 709, 2017
1192017
Cand1-Mediated Adaptive Exchange Mechanism Enables Variation in F-Box Protein Expression
DRJ Liu X, Reitsma JM, Mamrosh JL, Zhang Y, Straube R
Mol Cell. 69 (5), 773-786, 2018
1132018
Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle
R Mosadeghi, KM Reichermeier, M Winkler, A Schreiber, JM Reitsma, ...
Elife 5, e12102, 2016
1032016
High-Throughput Screen for Escherichia coli Heat Shock Protein 70 (Hsp70/DnaK) ATPase Assay in Low Volume by Exploiting Energy Transfer
Y Miyata, L Chang, A Bainor, TJ McQuade, CP Walczak, Y Zhang, ...
Journal of biomolecular screening 15 (10), 1211-1219, 2010
672010
Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs
N Bai, KM Riching, A Makaju, H Wu, TM Acker, SC Ou, Y Zhang, X Shen, ...
Journal of Biological Chemistry 298 (4), 2022
502022
Epidithiodiketopiperazines inhibit protein degradation by targeting proteasome deubiquitinase Rpn11
J Li, Y Zhang, BDSS Dos Santos, F Wang, Y Ma, C Perez, Y Yang, J Peng, ...
Cell chemical biology 25 (11), 1350-1358. e9, 2018
442018
Isolating contributions from intersegmental transfer to DNA searching by alkyladenine DNA glycosylase
M Hedglin, Y Zhang, PJ O'Brien
Journal of Biological Chemistry, jbc. M113. 477018, 2013
372013
Crystal structure of Saccharomyces cerevisiae cytoplasmic thioredoxin reductase Trr1 reveals the structural basis for species-specific recognition of thioredoxin
Z Zhang, R Bao, Y Zhang, J Yu, CZ Zhou, Y Chen
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1794 (1), 124-128, 2009
272009
Structural and kinetic analysis of Saccharomyces cerevisiae thioredoxin Trx1: implications for the catalytic mechanism of GSSG reduced by the thioredoxin system
R Bao, Y Zhang, X Lou, CZ Zhou, Y Chen
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1794 (8), 1218-1223, 2009
262009
Repair of alkylation damage in eukaryotic chromatin depends on searching ability of alkyladenine DNA glycosylase
Y Zhang, PJ O’Brien
ACS chemical biology 10 (11), 2606-2615, 2015
212015
Structural and mechanistic analyses of yeast mitochondrial thioredoxin Trx3 reveal putative function of its additional cysteine residues
R Bao, Y Zhang, CZ Zhou, Y Chen
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1794 (4), 716-721, 2009
212009
Adaptive exchange sustains cullin–RING ubiquitin ligase networks and proper licensing of DNA replication
Y Zhang, M Jost, RA Pak, D Lu, J Li, B Lomenick, SD Garbis, CM Li, ...
Proceedings of the National Academy of Sciences 119 (36), e2205608119, 2022
182022
Probing the DNA structural requirements for facilitated diffusion
M Hedglin, Y Zhang, PJ O’Brien
Biochemistry 54 (2), 557-566, 2014
152014
Redesign of cosubstrate specificity and identification of important residues for substrate binding to hChAT
KD Green, VR Porter, Y Zhang, S Garneau-Tsodikova
Biochemistry 49 (29), 6219-6227, 2010
142010
Expression, purification, crystallization and preliminary X-ray diffraction analysis of thioredoxin Trx1 from Saccharomyces cerevisiae
Y Zhang, R Bao, CZ Zhou, Y Chen
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2008
142008
Expression, purification, crystallization and preliminary X-ray diffraction analysis of mitochondrial thioredoxin Trx3 from Saccharomyces cerevisiae
R Bao, Y Chen, Y Zhang, CZ Zhou
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2006
62006
Purification, crystallization and preliminary X-ray diffraction analysis of glutathionylated Trx1 C33S mutant from yeast
X Lou, Y Zhang, R Bao, CZ Zhou, Y Chen
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009
22009
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