| Anti-estrogen resistance in human breast tumors is driven by JAG1-NOTCH4-dependent cancer stem cell activity BM Simoes, CS O’Brien, R Eyre, A Silva, L Yu, A Sarmiento-Castro, ... Cell reports 12 (12), 1968-1977, 2015 | 202 | 2015 |
| Breast cancer, side population cells and ABCG2 expression KM Britton, R Eyre, IJ Harvey, K Stemke-Hale, D Browell, TWJ Lennard, ... Cancer letters 323 (1), 97-105, 2012 | 149 | 2012 |
| Epidemiology of bone tumours in children and young adults R Eyre, RG Feltbower, E Mubwandarikwa, TOB Eden, RJQ McNally Pediatric blood & cancer 53 (6), 941-952, 2009 | 140 | 2009 |
| Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling R Eyre, DG Alférez, A Santiago-Gómez, K Spence, JC McConnell, C Hart, ... Nature communications 10 (1), 5016, 2019 | 138 | 2019 |
| White matter microstructural abnormalities in euthymic bipolar disorder KAN Macritchie, AJ Lloyd, ME Bastin, K Vasudev, P Gallagher, R Eyre, ... The British Journal of Psychiatry 196 (1), 52-58, 2010 | 95 | 2010 |
| Cisplatin selects for stem-like cells in osteosarcoma by activating Notch signaling L Yu, Z Fan, S Fang, J Yang, T Gao, BM Simões, R Eyre, W Guo, ... oncotarget 7 (22), 33055, 2016 | 80 | 2016 |
| The epidemiology of bone cancer in 0-39 year olds in northern England, 1981-2002 R Eyre, RG Feltbower, PW James, K Blakey, E Mubwandarikwa, ... BMC cancer 10, 1-7, 2010 | 69 | 2010 |
| Reversing paclitaxel resistance in ovarian cancer cells via inhibition of the ABCB1 expressing side population R Eyre, I Harvey, K Stemke-Hale, TWJ Lennard, A Tyson-Capper, ... Tumor Biology 35, 9879-9892, 2014 | 60 | 2014 |
| Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts D Lefley, F Howard, F Arshad, S Bradbury, H Brown, C Tulotta, R Eyre, ... Breast Cancer Research 21, 1-21, 2019 | 59 | 2019 |
| Patient-derived mammosphere and xenograft tumour initiation correlates with progression to metastasis R Eyre, DG Alférez, K Spence, M Kamal, FL Shaw, BM Simões, ... Journal of mammary gland biology and neoplasia 21, 99-109, 2016 | 59 | 2016 |
| Incidence and survival of childhood bone cancer in northern England and the West Midlands, 1981–2002 R Eyre, RG Feltbower, E Mubwandarikwa, HC Jenkinson, S Parkes, ... British journal of cancer 100 (1), 188-193, 2009 | 50 | 2009 |
| Enrichment of human osteosarcoma stem cells based on hTERT transcriptional activity L Yu, S Liu, C Zhang, B Zhang, BM Simões, R Eyre, Y Liang, H Yan, Z Wu, ... Oncotarget 4 (12), 2326, 2013 | 41 | 2013 |
| Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer BM Simões, A Santiago-Gómez, C Chiodo, T Moreira, D Conole, S Lovell, ... Oncogene 39 (25), 4896-4908, 2020 | 37 | 2020 |
| The notch pathway promotes osteosarcoma progression through activation of ephrin reverse signaling L Yu, K Xia, T Gao, J Chen, Z Zhang, X Sun, BM Simões, R Eyre, Z Fan, ... Molecular Cancer Research 17 (12), 2383-2394, 2019 | 36 | 2019 |
| Increased expression of interleukin-1 receptor characterizes anti-estrogen-resistant ALDH+ breast cancer stem cells A Sarmiento-Castro, E Caamaño-Gutiérrez, AH Sims, NJ Hull, MI James, ... Stem Cell Reports 15 (2), 307-316, 2020 | 33 | 2020 |
| The temporal and spatial expression patterns of ABCG2 in the developing human heart M Alfakir, N Dawe, R Eyre, A Tyson-Capper, K Britton, SC Robson, ... International journal of cardiology 156 (2), 133-138, 2012 | 30 | 2012 |
| Early years postgraduate surgical training programmes in the UK are failing to meet national quality standards: An analysis from the ASiT/BOTA Lost Tribe prospective cohort … JC Glasbey, RL Harries, AJ Beamish, VJ Gokani, H Mohan, AP Williams, ... International Journal of Surgery 52, 376-382, 2018 | 21 | 2018 |
| A dormant sub-population expressing interleukin-1 receptor characterises anti-estrogen resistant ALDH+ breast cancer stem cells A Sarmiento-Castro, E Caamaño-Gutiérrez, AH Sims, MI James, ... BiorXiv, 821876, 2019 | 3 | 2019 |
| Sulforadex targets breast cancer stem-like cells in patient-derived cells and xenograft tumors BM Simões, D Alferez, R Eyre, K Spence, A Santiago-Gomez, I Tanaka, ... Cancer Research 75 (15_Supplement), 2319-2319, 2015 | 3 | 2015 |
| EACR-MRS conference on seed and soil: in vivo models of metastasis I Teles Alves, N Cohen, PG Ersan, R Eyre, I Godet, D Holovanchuk, ... Clinical & Experimental Metastasis 34, 449-456, 2017 | 1 | 2017 |