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Robert Lochhead, PhD
Robert Lochhead, PhD
Associate Professor, Medical College of Wisconsin Department of Microbiology and Immunology
Verified email at mcw.edu
Title
Cited by
Cited by
Year
Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis
BL Jutras, RB Lochhead, ZA Kloos, J Biboy, K Strle, CJ Booth, SK Govers, ...
Proceedings of the National Academy of Sciences 116 (27), 13498-13507, 2019
1642019
Lyme arthritis: linking infection, inflammation and autoimmunity
RB Lochhead, K Strle, SL Arvikar, JJ Weis, AC Steere
Nature Reviews Rheumatology 17 (8), 449-461, 2021
1092021
Quorum sensing primes the oxidative stress response in the insect endosymbiont, Sodalis glossinidius
MH Pontes, M Babst, R Lochhead, K Oakeson, K Smith, C Dale
PloS one 3 (10), e3541, 2008
572008
MicroRNA-146a Provides Feedback Regulation of Lyme Arthritis but Not Carditis during Infection with Borrelia burgdorferi
RB Lochhead, Y Ma, JF Zachary, D Baltimore, JL Zhao, JH Weis, ...
PLoS pathogens 10 (6), e1004212, 2014
512014
Endothelial cells and fibroblasts amplify the arthritogenic type I IFN response in murine Lyme disease and are major sources of chemokines in Borrelia burgdorferi-infected …
RB Lochhead, FL Sonderegger, Y Ma, JE Brewster, D Cornwall, ...
The Journal of Immunology 189 (5), 2488-2501, 2012
482012
Interferon‐gamma production in Lyme arthritis synovial tissue promotes differentiation of fibroblast‐like synoviocytes into immune effector cells
RB Lochhead, D Ordoñez, SL Arvikar, JM Aversa, LS Oh, B Heyworth, ...
Cellular microbiology 21 (2), e12992, 2019
472019
Robust interferon signature and suppressed tissue repair gene expression in synovial tissue from patients with postinfectious, Borrelia burgdorferi‐induced Lyme …
RB Lochhead, SL Arvikar, JM Aversa, RI Sadreyev, K Strle, AC Steere
Cellular microbiology 21 (2), e12954, 2019
472019
MicroRNA expression shows inflammatory dysregulation and tumor‐like proliferative responses in joints of patients with postinfectious Lyme arthritis
RB Lochhead, K Strle, ND Kim, MJ Kohler, SL Arvikar, JM Aversa, ...
Arthritis & Rheumatology 69 (5), 1100-1110, 2017
442017
Borrelia burgdorferi Arthritis–Associated Locus Bbaa1 Regulates Lyme Arthritis and K/B× N Serum Transfer Arthritis through Intrinsic Control of Type I IFN Production
Y Ma, KKC Bramwell, RB Lochhead, JK Paquette, JF Zachary, JH Weis, ...
The Journal of Immunology 193 (12), 6050-6060, 2014
322014
Antagonistic interplay between microRNA-155 and IL-10 during Lyme carditis and arthritis
RB Lochhead, JF Zachary, L Dalla Rosa, Y Ma, JH Weis, RM O’Connell, ...
PLoS One 10 (8), e0135142, 2015
312015
Autoimmunity to synovial extracellular matrix proteins in patients with postinfectious Lyme arthritis
K Kanjana, K Strle, RB Lochhead, A Pianta, LM Mateyka, Q Wang, ...
The Journal of Clinical Investigation 133 (17), 2023
192023
Correlation of Lyme disease–associated IgG4 autoantibodies with synovial pathology in antibiotic‐refractory Lyme arthritis
KB Sulka, K Strle, JT Crowley, RB Lochhead, R Anthony, AC Steere
Arthritis & Rheumatology 70 (11), 1835-1846, 2018
192018
Report of the pathogenesis and pathophysiology of Lyme disease subcommittee of the HHS Tick Borne Disease Working Group
ST Donta, LJ States, WA Adams, T Bankhead, N Baumgarth, ME Embers, ...
Frontiers in Medicine 8, 643235, 2021
122021
Peptidoglycan in osteoarthritis synovial tissue is associated with joint inflammation
MN Holub, A Wahhab, JR Rouse, R Danner, LG Hackner, CB Duris, ...
Arthritis Research & Therapy 26 (1), 77, 2024
102024
Cell‐Mediated Cytotoxicity in Lyme Arthritis
D Ordóñez, RB Lochhead, K Strle, A Pianta, S Arvikar, I Van Rhijn, ...
Arthritis & Rheumatology 75 (5), 782-793, 2023
62023
HLA‐DR–Expressing Fibroblast‐Like Synoviocytes Are Inducible Antigen Presenting Cells That Present Autoantigens in Lyme Arthritis
JR Rouse, R Danner, A Wahhab, M Pereckas, C Nguyen, ME McClune, ...
ACR open rheumatology 6 (10), 678-689, 2024
32024
Immune fibroblasts are unconventional antigen presenting cells and nonprofessional phagocytes in Lyme arthritis
RB Lochhead, R Danner, A Wahhab, J Rouse
The Journal of Immunology 204 (1_Supplement), 148.29-148.29, 2020
22020
Extracellular micrornas in synovial fluid reveal a marked proliferative signature in patients with antibiotic-refractory lyme arthritis
RB Lochhead, ND Kim, S Arvikar, K Strle, AC Steere
ARTHRITIS & RHEUMATOLOGY 67, 2015
22015
Identification of Major Histocompatibility Complex Class II Epitopes From Lyme Autoantigen Apolipoprotein B-100 and Borrelia burgdorferi Mcp4 in Murine Lyme …
R Danner, LM Prochniak, M Pereckas, JR Rouse, A Wahhab, LG Hackner, ...
The Journal of Infectious Diseases 230 (Supplement_1), S27-S39, 2024
12024
Human leukocyte antigen HLA-DR-expressing fibroblast-like synoviocytes are inducible antigen presenting cells that present autoantigens in Lyme arthritis
JR Rouse, R Danner, A Wahhab, M Pereckas, ME McClune, AC Steere, ...
bioRxiv, 2023
12023
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