Low data drug discovery with one-shot learning H Altae-Tran, B Ramsundar, AS Pappu, V Pande ACS central science 3 (4), 283-293, 2017 | 925 | 2017 |
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies NA Doria-Rose, CA Schramm, J Gorman, PL Moore, JN Bhiman, ... Nature 509 (7498), 55-62, 2014 | 818 | 2014 |
Diverse enzymatic activities mediate antiviral immunity in prokaryotes L Gao, H Altae-Tran, F Böhning, KS Makarova, M Segel, JL Schmid-Burgk, ... Science 369 (6507), 1077-1084, 2020 | 422 | 2020 |
Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies T Zhou, J Zhu, X Wu, S Moquin, B Zhang, P Acharya, IS Georgiev, ... Immunity 39 (2), 245-258, 2013 | 391 | 2013 |
The widespread IS200/IS605 transposon family encodes diverse programmable RNA-guided endonucleases H Altae-Tran, S Kannan, FE Demircioglu, R Oshiro, SP Nety, LJ McKay, ... Science 374 (6563), 57-65, 2021 | 275 | 2021 |
Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization IS Georgiev, NA Doria-Rose, T Zhou, Y Do Kwon, RP Staupe, S Moquin, ... Science 340 (6133), 751-756, 2013 | 267 | 2013 |
Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies TB Kepler, HX Liao, SM Alam, R Bhaskarabhatla, R Zhang, C Yandava, ... Cell host & microbe 16 (3), 304-313, 2014 | 166 | 2014 |
Population-scale longitudinal mapping of COVID-19 symptoms, behaviour and testing WE Allen, H Altae-Tran, J Briggs, X Jin, G McGee, A Shi, R Raghavan, ... Nature human behaviour 4 (9), 972-982, 2020 | 139 | 2020 |
Compact RNA editors with small Cas13 proteins S Kannan, H Altae-Tran, X Jin, VJ Madigan, R Oshiro, KS Makarova, ... Nature biotechnology 40 (2), 194-197, 2022 | 137 | 2022 |
Fanzor is a eukaryotic programmable RNA-guided endonuclease M Saito, P Xu, G Faure, S Maguire, S Kannan, H Altae-Tran, S Vo, ... Nature 620 (7974), 660-668, 2023 | 120 | 2023 |
Dual modes of CRISPR-associated transposon homing M Saito, A Ladha, J Strecker, G Faure, E Neumann, H Altae-Tran, ... Cell 184 (9), 2441-2453. e18, 2021 | 108 | 2021 |
Mapping polyclonal HIV-1 antibody responses via next-generation neutralization fingerprinting NA Doria-Rose, HR Altae-Tran, RS Roark, SD Schmidt, MS Sutton, ... PLoS pathogens 13 (1), e1006148, 2017 | 62 | 2017 |
Uncovering the functional diversity of rare CRISPR-Cas systems with deep terascale clustering H Altae-Tran, S Kannan, AJ Suberski, KS Mears, FE Demircioglu, ... Science 382 (6673), eadi1910, 2023 | 55 | 2023 |
Cryo-EM structure of the transposon-associated TnpB enzyme R Nakagawa, H Hirano, SN Omura, S Nety, S Kannan, H Altae-Tran, ... Nature 616 (7956), 390-397, 2023 | 52 | 2023 |
Cargo Genes of Tn7-Like Transposons Comprise an Enormous Diversity of Defense Systems, Mobile Genetic Elements, and Antibiotic Resistance Genes S Benler, G Faure, H Altae-Tran, S Shmakov, F Zhang, E Koonin MBio 12 (6), e02938-21, 2021 | 51 | 2021 |
Building an international consortium for tracking coronavirus health status E Segal, F Zhang, X Lin, G King, O Shalem, S Shilo, WE Allen, ... Nature medicine 26 (8), 1161-1165, 2020 | 41 | 2020 |
Diversity, evolution, and classification of the RNA-guided nucleases TnpB and Cas12 H Altae-Tran, SA Shmakov, KS Makarova, YI Wolf, S Kannan, F Zhang, ... Proceedings of the National Academy of Sciences 120 (48), e2308224120, 2023 | 27 | 2023 |
Structure of the IscB–ωRNA ribonucleoprotein complex, the likely ancestor of CRISPR-Cas9 K Kato, S Okazaki, S Kannan, H Altae-Tran, F Esra Demircioglu, ... Nature Communications 13 (1), 6719, 2022 | 24 | 2022 |
Structure and engineering of the minimal type VI CRISPR-Cas13bt3 R Nakagawa, S Kannan, H Altae-Tran, SN Takeda, A Tomita, H Hirano, ... Molecular cell 82 (17), 3178-3192. e5, 2022 | 24 | 2022 |
Structure of the OMEGA nickase IsrB in complex with ωRNA and target DNA S Hirano, K Kappel, H Altae-Tran, G Faure, ME Wilkinson, S Kannan, ... Nature 610 (7932), 575-581, 2022 | 22 | 2022 |