| High-throughput screen for novel antimicrobials using a whole animal infection model TI Moy, AL Conery, J Larkins-Ford, G Wu, R Mazitschek, G Casadei, ... ACS chemical biology 4 (7), 527-533, 2009 | 265 | 2009 |
| Pseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and death NV Kirienko, DR Kirienko, J Larkins-Ford, C Wählby, G Ruvkun, ... Cell host & microbe 13 (4), 406-416, 2013 | 229 | 2013 |
| OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development H Komatsu, MY Chao, J Larkins-Ford, ME Corkins, GA Somers, T Tucey, ... PLoS biology 6 (8), e196, 2008 | 176 | 2008 |
| Sexual and social stimuli elicit rapid and contrasting genomic responses ME Cummings, J Larkins-Ford, CRL Reilly, RY Wong, M Ramsey, ... Proceedings of the Royal Society B: Biological Sciences 275 (1633), 393-402, 2008 | 153 | 2008 |
| C. elegans Notch signaling regulates adult chemosensory response and larval molting quiescence K Singh, MY Chao, GA Somers, H Komatsu, ME Corkins, J Larkins-Ford, ... Current Biology 21 (10), 825-834, 2011 | 150 | 2011 |
| Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay I Okoli, JJ Coleman, E Tempakakis, WF An, E Holson, F Wagner, ... PloS one 4 (9), e7025, 2009 | 146 | 2009 |
| Selective degradation of host RNA polymerase II transcripts by influenza A virus PA-X host shutoff protein DA Khaperskyy, S Schmaling, J Larkins-Ford, C McCormick, MM Gaglia PLoS pathogens 12 (2), e1005427, 2016 | 144 | 2016 |
| Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis M Cokol, N Kuru, E Bicak, J Larkins-Ford, BB Aldridge Science advances 3 (10), e1701881, 2017 | 136 | 2017 |
| Whole animal automated platform for drug discovery against multi-drug resistant Staphylococcus aureus R Rajamuthiah, BB Fuchs, E Jayamani, Y Kim, J Larkins-Ford, A Conery, ... PloS one 9 (2), e89189, 2014 | 114 | 2014 |
| Stimulation of Host Immune Defenses by a Small Molecule Protects C. elegans from Bacterial Infection R Pukkila-Worley, R Feinbaum, NV Kirienko, J Larkins-Ford, AL Conery, ... PLoS genetics 8 (6), e1002733, 2012 | 105 | 2012 |
| High-and low-throughput scoring of fat mass and body fat distribution in C. elegans C Wählby, AL Conery, MA Bray, L Kamentsky, J Larkins-Ford, ... Methods 68 (3), 492-499, 2014 | 81 | 2014 |
| Insect-derived cecropins display activity against Acinetobacter baumannii in a whole-animal high-throughput Caenorhabditis elegans model E Jayamani, R Rajamuthiah, J Larkins-Ford, BB Fuchs, AL Conery, ... Antimicrobial agents and chemotherapy 59 (3), 1728-1737, 2015 | 69 | 2015 |
| High‐Throughput Screening for Novel Anti‐Infectives Using a C. elegans Pathogenesis Model AL Conery, J Larkins‐Ford, FM Ausubel, NV Kirienko Current protocols in chemical biology 6 (1), 25-37, 2014 | 61 | 2014 |
| A new antibiotic with potent activity targets MscL I Iscla, R Wray, P Blount, J Larkins-Ford, AL Conery, FM Ausubel, S Ramu, ... The Journal of antibiotics 68 (7), 453-462, 2015 | 59 | 2015 |
| Systematic measurement of combination-drug landscapes to predict in vivo treatment outcomes for tuberculosis J Larkins-Ford, T Greenstein, N Van, YN Degefu, MC Olson, A Sokolov, ... Cell systems 12 (11), 1046-1063. e7, 2021 | 56 | 2021 |
| lin-12 Notch functions in the adult nervous system of C. elegans MY Chao, J Larkins-Ford, TM Tucey, AC Hart BMC neuroscience 6, 1-12, 2005 | 47 | 2005 |
| Transcriptomic signatures predict regulators of drug synergy and clinical regimen efficacy against tuberculosis S Ma, S Jaipalli, J Larkins-Ford, J Lohmiller, BB Aldridge, DR Sherman, ... MBio 10 (6), 10.1128/mbio. 02627-19, 2019 | 45 | 2019 |
| Morphological profiling of tubercle bacilli identifies drug pathways of action TC Smith, KM Pullen, MC Olson, ME McNellis, I Richardson, S Hu, ... Proceedings of the National Academy of Sciences 117 (31), 18744-18753, 2020 | 42 | 2020 |
| Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components D Tomkiewicz, G Casadei, J Larkins-Ford, TI Moy, J Garner, JB Bremner, ... Antimicrobial agents and chemotherapy 54 (8), 3219-3224, 2010 | 38 | 2010 |
| Design principles to assemble drug combinations for effective tuberculosis therapy using interpretable pairwise drug response measurements J Larkins-Ford, YN Degefu, N Van, A Sokolov, BB Aldridge Cell Reports Medicine 3 (9), 2022 | 36 | 2022 |
Gary RuvkunProfessor of Genetics, Harvard Medical SchoolVerified email at molbio.mgh.harvard.edu
