Design, synthesis, biological activity and structure-activity relationship studies of chalcone derivatives as potential anti-Candida agents JT Andrade, FRS Santos, WG Lima, CDF Sousa, LSFM Oliveira, ... The Journal of antibiotics 71 (8), 702-712, 2018 | 55 | 2018 |
Identification of Zika virus NS2B-NS3 protease inhibitors by structure-based virtual screening and drug repurposing approaches FRS Santos, DAF Nunes, WG Lima, D Davyt, LL Santos, AG Taranto, ... Journal of Chemical Information and Modeling 60 (2), 731-737, 2019 | 50 | 2019 |
NS2B‐NS3 protease inhibitors as promising compounds in the development of antivirals against Zika virus: A systematic review DAF Nunes, FRS Santos, STD da Fonseca, WG de Lima, WSC Nizer, ... Journal of Medical Virology 94 (2), 442-453, 2022 | 28 | 2022 |
Identification of a potential zika virus inhibitor targeting NS5 methyltransferase using virtual screening and molecular dynamics simulations FRS Santos, WG Lima, EHB Maia, LC Assis, D Davyt, AG Taranto, ... Journal of Chemical Information and Modeling 60 (2), 562-568, 2020 | 21 | 2020 |
γ-Benzylidene digoxin derivatives synthesis and molecular modeling: Evaluation of anticancer and the Na, K-ATPase activity effect SLG Alves, N Paixão, LGR Ferreira, FRS Santos, LDR Neves, GC Oliveira, ... Bioorganic & Medicinal Chemistry 23 (15), 4397-4404, 2015 | 20 | 2015 |
Neuraminidase is a host‐directed approach to regulate neutrophil responses in sepsis and COVID‐19 R de Oliveira Formiga, FC Amaral, CF Souza, DAGB Mendes, ... British Journal of Pharmacology 180 (11), 1460-1481, 2023 | 11 | 2023 |
Bauhinia holophylla (Bong.) Steud. leaves-derived extracts as potent anti-dengue serotype 2 M Dos Santos, TR Teixeira, FRS Santos, WG Lima, AC Ferraz, NL Silva, ... Natural Product Research 35 (16), 2804-2809, 2021 | 10 | 2021 |
Triazole‑chalcones: lack of antibacterial, anti‑candida, and anti‑dengue virus activities M dos Santos, FR Santos, AC Ferraz, JT Andrade, KM Herrera, WG Lima, ... Journal of Pharmaceutical Negative Results¦ Volume 9 (1), 40, 2018 | 10 | 2018 |
Mutational profile confers increased stability of SARS-CoV-2 spike protein in Brazilian isolates FRS Santos, MSP De Azevedo, M Bielavsky, HHM Da Costa, DG Ribeiro, ... Journal of Biomolecular Structure and Dynamics 40 (23), 13184-13189, 2022 | 7 | 2022 |
Synthesis and Evaluation of the in vitro Antimicrobial Activity of Triazoles, Morpholines and Thiosemicarbazones FRS Santos, JT Andrade, CDF Sousa, JS Fernandes, LF Carmo, ... Medicinal Chemistry 15 (1), 38-50, 2019 | 7 | 2019 |
A 5-lipoxygenase inhibitor, zileuton, modulates host immune responses and improves lung function in a model of severe acute respiratory syndrome (SARS) induced by betacoronavirus RD Pereira, RAN Rabelo, NFM Oliveira, SLT Porto, ACSP Andrade, ... Viruses 15 (10), 2049, 2023 | 6 | 2023 |
Virucidal antiviral activity of Maytenus quadrangulata extract against Mayaro virus: Evidence for the presence of catechins DA de Fátima Nunes, GFM Lopes, WS da Cruz Nizer, MG de Aguilar, ... Journal of Ethnopharmacology 311, 116436, 2023 | 5 | 2023 |
Anti-Mayaro virus activity of a hydroethanolic extract from Fridericia chica (Bonpl.) LG Lohmann leaves GFM Lopes, WG Lima, FRS Santos, DAF Nunes, MJF Passos, ... Journal of Ethnopharmacology 299, 115685, 2022 | 4 | 2022 |
The glycosaminoglycan-binding chemokine fragment CXCL9 (74–103) reduces inflammation and tissue damage in mouse models of coronavirus infection VLS Oliveira, CM Queiroz-Junior, D Hoorelbeke, FRS Santos, IM Chaves, ... Frontiers in Immunology 15, 1378591, 2024 | 3 | 2024 |
Neuropsychiatric sequelae in an experimental model of post-COVID syndrome in mice JC Pimenta, VA Beltrami, BDS Oliveira, CM Queiroz-Junior, J Barsalini, ... BioRxiv, 2024.01. 10.575003, 2024 | 3 | 2024 |
Targeting PI3Kγ pathway for treating dengue virus infection FRS Santos, DF Valadão, JL Bambirra, TP Moreira, CDF de Sousa, ... Microbial pathogenesis 197, 107060, 2024 | 2 | 2024 |
Angiotensin-(1–7) decreases inflammation and lung damage caused by betacoronavirus infection in mice EBS Lima, AFS Carvalho, I Zaidan, AHA Monteiro, C Cardoso, ES Lara, ... Inflammation Research 73 (11), 2009-2022, 2024 | 2 | 2024 |
siRNA lipid nanoparticles for CXCL12 silencing modulate brain immune response during Zika infection PAC Costa, WN da Silva, PHDM Prazeres, HAS Ferreira, NJA da Silva, ... Biomedicine & Pharmacotherapy 170, 115981, 2024 | 2 | 2024 |
Identification of zika virus ns1-derived peptides with potential applications in serological tests CR Prudencio, V Gomes da Costa, LB Rocha, HHM da Costa, DJB Orts, ... Viruses 15 (3), 654, 2023 | 2 | 2023 |
Discovery of a 2′-Fluoro, 2′-bromouridine phosphoramidate prodrug exhibiting anti-yellow fever virus activity in culture and in mice JC LeCher, K Zandi, VV Costa, F Amblard, S Tao, D Patel, S Lee, ... Microorganisms 10 (11), 2098, 2022 | 2 | 2022 |