| Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors EJ Chen, AG Sowalsky, S Gao, C Cai, O Voznesensky, R Schaefer, ... Clinical cancer research 21 (6), 1273-1280, 2015 | 200 | 2015 |
| Lysine-specific demethylase 1 has dual functions as a major regulator of androgen receptor transcriptional activity C Cai, HH He, S Gao, S Chen, Z Yu, Y Gao, S Chen, MW Chen, J Zhang, ... Cell reports 9 (5), 1618-1627, 2014 | 152 | 2014 |
| Galeterone prevents androgen receptor binding to chromatin and enhances degradation of mutant androgen receptor Z Yu, C Cai, S Gao, NI Simon, HC Shen, SP Balk Clinical cancer research 20 (15), 4075-4085, 2014 | 107 | 2014 |
| Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer S Gao, S Chen, D Han, Z Wang, M Li, W Han, A Besschetnova, M Liu, ... Nature genetics 52 (10), 1011-1017, 2020 | 106 | 2020 |
| Androgen receptor tumor suppressor function is mediated by recruitment of retinoblastoma protein S Gao, Y Gao, HH He, D Han, W Han, A Avery, JA Macoska, X Liu, ... Cell reports 17 (4), 966-976, 2016 | 103 | 2016 |
| Reactivation of androgen receptor-regulated lipid biosynthesis drives the progression of castration-resistant prostate cancer W Han, S Gao, D Barrett, M Ahmed, D Han, JA Macoska, HH He, C Cai Oncogene 37 (6), 710-721, 2018 | 102 | 2018 |
| LSD1-mediated epigenetic reprogramming drives CENPE expression and prostate cancer progression Y Liang, M Ahmed, H Guo, F Soares, JT Hua, S Gao, C Lu, C Poon, ... Cancer research 77 (20), 5479-5490, 2017 | 88 | 2017 |
| PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy CL Hsieh, G Botta, S Gao, T Li, EM Van Allen, DJ Treacy, C Cai, HH He, ... Cancer research 75 (10), 1944-1948, 2015 | 59 | 2015 |
| TMPRSS2-ERG activates NO-cGMP signaling in prostate cancer cells F Zhou, S Gao, D Han, W Han, S Chen, S Patalano, JA Macoska, HH He, ... Oncogene 38 (22), 4397-4411, 2019 | 54 | 2019 |
| ErbB2 signaling increases androgen receptor expression in abiraterone-resistant prostate cancer S Gao, H Ye, S Gerrin, H Wang, A Sharma, S Chen, A Patnaik, ... Clinical Cancer Research 22 (14), 3672-3682, 2016 | 50 | 2016 |
| Forkhead domain mutations in FOXA1 drive prostate cancer progression S Gao, S Chen, D Han, D Barrett, W Han, M Ahmed, S Patalano, ... Cell research 29 (9), 770-772, 2019 | 39 | 2019 |
| Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress Y Liao, CH Chen, T Xiao, B de la Peña Avalos, EV Dray, C Cai, S Gao, ... Proceedings of the National Academy of Sciences 119 (3), e2105898119, 2022 | 36 | 2022 |
| LSD1 Inhibition Disrupts Super-Enhancer–Driven Oncogenic Transcriptional Programs in Castration-Resistant Prostate Cancer M Li, M Liu, W Han, Z Wang, D Han, S Patalano, JA Macoska, SP Balk, ... Cancer research 83 (10), 1684-1698, 2023 | 32 | 2023 |
| RB1 loss in castration-resistant prostate cancer confers vulnerability to LSD1 inhibition W Han, M Liu, D Han, M Li, AA Toure, Z Wang, A Besschetnova, ... Oncogene 41 (6), 852-864, 2022 | 30 | 2022 |
| ZBTB7A mediates the transcriptional repression activity of the androgen receptor in prostate cancer D Han, S Chen, W Han, S Gao, JN Owiredu, M Li, SP Balk, HH He, C Cai Cancer research 79 (20), 5260-5271, 2019 | 30 | 2019 |
| Soluble guanylyl cyclase α1 and p53 cytoplasmic sequestration and down-regulation in prostate cancer C Cai, CL Hsieh, S Gao, A Kannan, M Bhansali, K Govardhan, R Dutta, ... Molecular endocrinology 26 (2), 292-307, 2012 | 28 | 2012 |
| Exploiting the tumor-suppressive activity of the androgen receptor by CDK4/6 inhibition in castration-resistant prostate cancer W Han, M Liu, D Han, AA Toure, M Li, A Besschetnova, Z Wang, ... Molecular Therapy 30 (4), 1628-1644, 2022 | 25 | 2022 |
| A peptide against soluble guanylyl cyclase α1: a new approach to treating prostate cancer S Gao, CL Hsieh, M Bhansali, A Kannan, L Shemshedini PloS one 8 (5), e64189, 2013 | 25 | 2013 |
| Exploiting AR-regulated drug transport to induce sensitivity to the survivin inhibitor YM155 MD Nyquist, A Corella, J Burns, I Coleman, S Gao, R Tharakan, L Riggan, ... Molecular Cancer Research 15 (5), 521-531, 2017 | 22 | 2017 |
| Zinc finger 280B regulates sGCα1 and p53 in prostate cancer cells S Gao, CL Hsieh, J Zhou, L Shemshedini PloS one 8 (11), e78766, 2013 | 19 | 2013 |
Changmeng CaiUniversity of Massachusetts BostonVerified email at umb.edu