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Yosephine Gumulya
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Genetically programmed chiral organoborane synthesis
SBJ Kan, X Huang, Y Gumulya, K Chen, FH Arnold
Nature 552 (7683), 132-136, 2017
2942017
Iterative saturation mutagenesis accelerates laboratory evolution of enzyme stereoselectivity: rigorous comparison with traditional methods
MT Reetz, S Prasad, JD Carballeira, Y Gumulya, M Bocola
Journal of the American Chemical Society 132 (26), 9144-9152, 2010
2662010
Recent progress in biohydrometallurgy and microbial characterisation
AH Kaksonen, NJ Boxall, Y Gumulya, HN Khaleque, C Morris, T Bohu, ...
Hydrometallurgy 180, 7-25, 2018
1962018
Increasing the stability of an enzyme toward hostile organic solvents by directed evolution based on iterative saturation mutagenesis using the B-FIT method
MT Reetz, P Soni, L Fernández, Y Gumulya, JD Carballeira
Chemical communications 46 (45), 8657-8658, 2010
1962010
Exploring the past and the future of protein evolution with ancestral sequence reconstruction: the ‘retro’approach to protein engineering
Y Gumulya, EMJ Gillam
Biochemical Journal 474 (1), 1-19, 2017
1562017
Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates
J Sanchis, L Fernández, JD Carballeira, J Drone, Y Gumulya, ...
Applied microbiology and biotechnology 81, 387-397, 2008
1562008
Prospective directions for biohydrometallurgy
AH Kaksonen, X Deng, T Bohu, L Zea, HN Khaleque, Y Gumulya, ...
Hydrometallurgy 195, 105376, 2020
992020
In a quest for engineering acidophiles for biomining applications: challenges and opportunities
Y Gumulya, NJ Boxall, HN Khaleque, V Santala, RP Carlson, ...
Genes 9 (2), 116, 2018
982018
Many pathways in laboratory evolution can lead to improved enzymes: how to escape from local minima
Y Gumulya, J Sanchis, MT Reetz
ChemBioChem 13 (7), 1060-1066, 2012
842012
Urban mining of lithium-ion batteries in Australia: Current state and future trends
NJ Boxall, S King, KY Cheng, Y Gumulya, W Bruckard, AH Kaksonen
Minerals Engineering 128, 45-55, 2018
722018
Enhancing the thermal robustness of an enzyme by directed evolution: least favorable starting points and inferior mutants can map superior evolutionary pathways
Y Gumulya, MT Reetz
ChemBioChem 12 (16), 2502-2510, 2011
712011
Toward sustainable space exploration: a roadmap for harnessing the power of microorganisms
R Santomartino, NJH Averesch, M Bhuiyan, CS Cockell, J Colangelo, ...
Nature communications 14 (1), 1391, 2023
702023
Evaluation of the laccase from Myceliophthora thermophila as industrial biocatalyst for polymerization reactions
F Hollmann, Y Gumulya, C Tölle, A Liese, O Thum
Macromolecules 41 (22), 8520-8524, 2008
592008
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
P Brown, Y Zhou
Database 2019, baz085, 2019
402019
In situ resource utilisation: the potential for space biomining
Y Gumulya, L Zea, AH Kaksonen
Minerals Engineering 176, 107288, 2022
372022
Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP)
G Foley, A Mora, CM Ross, S Bottoms, L Sützl, ML Lamprecht, J Zaugg, ...
PLOS Computational Biology 18 (10), e1010633, 2022
322022
Determinants of thermostability in the cytochrome P450 fold
KL Harris, RES Thomson, SJ Strohmaier, Y Gumulya, EMJ Gillam
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1866 (1), 97-115, 2018
252018
Learning epistatic interactions from sequence-activity data to predict enantioselectivity
J Zaugg, Y Gumulya, AK Malde, M Bodén
Journal of computer-aided molecular design 31 (12), 1085-1096, 2017
252017
Engineering thermostable CYP2D enzymes for biocatalysis using combinatorial libraries of ancestors for directed evolution (CLADE)
Y Gumulya, W Huang, SA D'Cunha, KE Richards, RES Thomson, ...
ChemCatChem 11 (2), 841-850, 2019
212019
Ancestral sequence reconstruction of a cytochrome P450 family involved in chemical defense reveals the functional evolution of a promiscuous, xenobiotic-metabolizing enzyme in …
KL Harris, RES Thomson, Y Gumulya, G Foley, SE Carrera-Pacheco, ...
Molecular biology and evolution 39 (6), msac116, 2022
202022
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