Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis W Beaino, B Janssen, G Kooij, SMA van der Pol, B van Het Hof, ... Journal of neuroinflammation 14, 1-16, 2017 | 123 | 2017 |
Head-to-head comparison of DFO* and DFO chelators: selection of the best candidate for clinical 89Zr-immuno-PET M Chomet, M Schreurs, MJ Bolijn, M Verlaan, W Beaino, K Brown, ... European journal of nuclear medicine and molecular imaging 48, 694-707, 2021 | 74 | 2021 |
Combined VLA-4–targeted radionuclide therapy and immunotherapy in a mouse model of melanoma J Choi, W Beaino, RJ Fecek, KPL Fabian, CM Laymon, BF Kurland, ... Journal of Nuclear Medicine 59 (12), 1843-1849, 2018 | 68 | 2018 |
Identification of the allosteric P2X7 receptor antagonist [11C]SMW139 as a PET tracer of microglial activation B Janssen, DJ Vugts, SM Wilkinson, D Ory, S Chalon, JJM Hoozemans, ... Scientific reports 8 (1), 6580, 2018 | 67 | 2018 |
Theranostic nanoemulsions for macrophage COX-2 inhibition in a murine inflammation model SK Patel, W Beaino, CJ Anderson, JM Janjic Clinical immunology 160 (1), 59-70, 2015 | 66 | 2015 |
The P2X7 receptor tracer [11C]SMW139 as an in vivo marker of neuroinflammation in multiple sclerosis: a first-in man study MHJ Hagens, SSV Golla, B Janssen, DJ Vugts, W Beaino, AD Windhorst, ... European journal of nuclear medicine and molecular imaging 47, 379-389, 2020 | 64 | 2020 |
PET imaging of very late antigen-4 in melanoma: comparison of 68Ga-and 64Cu-labeled NODAGA and CB-TE1A1P-LLP2A conjugates W Beaino, CJ Anderson Journal of Nuclear Medicine 55 (11), 1856-1863, 2014 | 64 | 2014 |
The role of 89Zr-immuno-PET in navigating and derisking the development of biopharmaceuticals GAMS van Dongen, W Beaino, AD Windhorst, GJC Zwezerijnen, ... Journal of Nuclear Medicine 62 (4), 438-445, 2021 | 61 | 2021 |
Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state A Villa, B Klein, B Janssen, J Pedragosa, G Pepe, B Zinnhardt, DJ Vugts, ... Theranostics 8 (19), 5400, 2018 | 58 | 2018 |
Altered secretory and neuroprotective function of the choroid plexus in progressive multiple sclerosis S Rodríguez-Lorenzo, DM Ferreira Francisco, R Vos, B van Het Hof, ... Acta neuropathologica communications 8, 1-13, 2020 | 54 | 2020 |
Evaluation of 68Ga- and 177Lu-DOTA-PEG4-LLP2A for VLA-4-Targeted PET Imaging and Treatment of Metastatic Melanoma W Beaino, JR Nedrow, CJ Anderson Molecular pharmaceutics 12 (6), 1929-1938, 2015 | 51 | 2015 |
Positron emission tomography imaging of macaques with tuberculosis identifies temporal changes in granuloma glucose metabolism and integrin α4β1–expressing immune cells JT Mattila, W Beaino, P Maiello, MT Coleman, AG White, CA Scanga, ... The Journal of Immunology 199 (2), 806-815, 2017 | 49 | 2017 |
Roles of Atox1 and p53 in the trafficking of copper-64 to tumor cell nuclei: implications for cancer therapy W Beaino, Y Guo, AJ Chang, CJ Anderson JBIC Journal of Biological Inorganic Chemistry 19, 427-438, 2014 | 48 | 2014 |
Ex vivo and in vivo evaluation of overexpressed VLA-4 in multiple myeloma using LLP2A imaging agents D Soodgupta, H Zhou, W Beaino, L Lu, M Rettig, M Snee, J Skeath, ... Journal of Nuclear Medicine 57 (4), 640-645, 2016 | 43 | 2016 |
α‐Synuclein Radiotracer Development and In Vivo Imaging: Recent Advancements and New Perspectives OM Alzghool, G van Dongen, E van de Giessen, L Schoonmade, ... Movement Disorders 37 (5), 936-948, 2022 | 41 | 2022 |
Towards PET imaging of the dynamic phenotypes of microglia W Beaino, B Janssen, DJ Vugts, HE de Vries, AD Windhorst Clinical & Experimental Immunology 206 (3), 282-300, 2021 | 38 | 2021 |
Folate receptor beta for macrophage imaging in rheumatoid arthritis MM Steinz, A Ezdoglian, F Khodadust, CFM Molthoff, M Srinivasarao, ... Frontiers in immunology 13, 819163, 2022 | 23 | 2022 |
In vivo inflammation imaging using a CB2R-targeted near infrared fluorescent probe S Zhang, P Shao, X Ling, L Yang, W Hou, SH Thorne, W Beaino, ... American journal of nuclear medicine and molecular imaging 5 (3), 246, 2015 | 23 | 2015 |
Novel Thienopyrimidine-Based PET Tracers for P2Y12 Receptor Imaging in the Brain B van der Wildt, B Janssen, A Pekošak, EJL Stéen, RC Schuit, ... ACS Chemical Neuroscience 12 (23), 4465-4474, 2021 | 21 | 2021 |
Characterization of a new rat model for chronic inflammatory demyelinating polyneuropathies S Brun, W Beaino, L Kremer, O Taleb, AG Mensah-Nyagan, CD Lam, ... Journal of neuroimmunology 278, 1-10, 2015 | 20 | 2015 |