| Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential: a revised road map for adult blood lineage commitment J Adolfsson, R Månsson, N Buza-Vidas, A Hultquist, K Liuba, CT Jensen, ... Cell 121 (2), 295-306, 2005 | 1687 | 2005 |
| Cell intrinsic alterations underlie hematopoietic stem cell aging DJ Rossi, D Bryder, JM Zahn, H Ahlenius, R Sonu, AJ Wagers, ... Proceedings of the National Academy of Sciences 102 (26), 9194-9199, 2005 | 1343 | 2005 |
| Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age DJ Rossi, D Bryder, J Seita, A Nussenzweig, J Hoeijmakers, IL Weissman Nature 447 (7145), 725-729, 2007 | 1326 | 2007 |
| Upregulation of Flt3 expression within the bone marrow Lin− Sca1+ c-kit+ stem cell compartment is accompanied by loss of self-renewal capacity J Adolfsson, OJ Borge, D Bryder, K Theilgaard-Mönch, ... Immunity 15 (4), 659-669, 2001 | 986 | 2001 |
| Hematopoietic stem cells: the paradigmatic tissue-specific stem cell D Bryder, DJ Rossi, IL Weissman The American journal of pathology 169 (2), 338-346, 2006 | 918 | 2006 |
| Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion I Beerman, D Bhattacharya, S Zandi, M Sigvardsson, IL Weissman, ... Proceedings of the National Academy of Sciences 107 (12), 5465-5470, 2010 | 776 | 2010 |
| Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy CJH Pronk, DJ Rossi, R Månsson, JL Attema, GL Norddahl, CKF Chan, ... Cell stem cell 1 (4), 428-442, 2007 | 757 | 2007 |
| Identification of Lin–Sca1+kit+CD34+Flt3– short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients L Yang, D Bryder, J Adolfsson, J Nygren, R Månsson, M Sigvardsson, ... Blood 105 (7), 2717-2723, 2005 | 681 | 2005 |
| Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9 PK Mandal, LMR Ferreira, R Collins, TB Meissner, CL Boutwell, M Friesen, ... Cell stem cell 15 (5), 643-652, 2014 | 626 | 2014 |
| Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR L Warren, D Bryder, IL Weissman, SR Quake Proceedings of the National Academy of Sciences 103 (47), 17807-17812, 2006 | 467 | 2006 |
| Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool E Sitnicka, D Bryder, K Theilgaard-Mönch, N Buza-Vidas, J Adolfsson, ... Immunity 17 (4), 463-472, 2002 | 380 | 2002 |
| NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements J Weischenfeldt, I Damgaard, D Bryder, K Theilgaard-Mönch, LA Thoren, ... Genes & development 22 (10), 1381-1396, 2008 | 307 | 2008 |
| Kit regulates maintenance of quiescent hematopoietic stem cells LA Thorén, K Liuba, D Bryder, JM Nygren, CT Jensen, H Qian, ... The Journal of Immunology 180 (4), 2045-2053, 2008 | 278 | 2008 |
| Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging GL Norddahl, CJ Pronk, M Wahlestedt, G Sten, JM Nygren, A Ugale, ... Cell stem cell 8 (5), 499-510, 2011 | 271 | 2011 |
| Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms B Tesi, J Davidsson, M Voss, E Rahikkala, TD Holmes, SCC Chiang, ... Blood, The Journal of the American Society of Hematology 129 (16), 2266-2279, 2017 | 224 | 2017 |
| Complementary signaling through flt3 and interleukin-7 receptor α is indispensable for fetal and adult B cell genesis E Sitnicka, C Brakebusch, IL Martensson, M Svensson, WW Agace, ... The Journal of experimental medicine 198 (10), 1495-1506, 2003 | 223 | 2003 |
| Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors CJH Pronk, OP Veiby, D Bryder, SEW Jacobsen Journal of Experimental Medicine 208 (8), 1563-1570, 2011 | 221 | 2011 |
| Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging DJ Rossi, J Seita, A Czechowicz, D Bhattacharya, D Bryder, IL Weissman Cell cycle 6 (19), 2371-2376, 2007 | 215 | 2007 |
| Rapid and efficient induction of functional astrocytes from human pluripotent stem cells I Canals, A Ginisty, E Quist, R Timmerman, J Fritze, G Miskinyte, E Monni, ... Nature methods 15 (9), 693-696, 2018 | 207 | 2018 |
| Involvement and functional impairment of the CD34+CD38−Thy-1+ hematopoietic stem cell pool in myelodysplastic syndromes with trisomy 8 L Nilsson, I Åstrand-Grundström, K Anderson, I Arvidsson, P Hokland, ... Blood, The Journal of the American Society of Hematology 100 (1), 259-267, 2002 | 204 | 2002 |
Irving WeissmanDirector, Institute of Stem Cell Biology and Regenerative MedicineVerified email at stanford.edu