| Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway VS Viswanathan, MJ Ryan, HD Dhruv, S Gill, OM Eichhoff, ... Nature 547 (7664), 453-457, 2017 | 1611 | 2017 |
| Correlating chemical sensitivity and basal gene expression reveals mechanism of action MG Rees, B Seashore-Ludlow, JH Cheah, DJ Adams, EV Price, S Gill, ... Nature chemical biology 12 (2), 109-116, 2016 | 804 | 2016 |
| Harnessing connectivity in a large-scale small-molecule sensitivity dataset B Seashore-Ludlow, MG Rees, JH Cheah, M Cokol, EV Price, ME Coletti, ... Cancer discovery 5 (11), 1210-1223, 2015 | 721 | 2015 |
| Predicting cancer-specific vulnerability via data-driven detection of synthetic lethality L Jerby-Arnon, N Pfetzer, YY Waldman, L McGarry, D James, E Shanks, ... Cell 158 (5), 1199-1209, 2014 | 314 | 2014 |
| Drug target commons: a community effort to build a consensus knowledge base for drug-target interactions J Tang, B Ravikumar, Z Alam, A Rebane, M Vähä-Koskela, G Peddinti, ... Cell chemical biology 25 (2), 224-229. e2, 2018 | 153 | 2018 |
| Validation and development of MTH1 inhibitors for treatment of cancer UW Berglund, K Sanjiv, H Gad, C Kalderen, T Koolmeister, T Pham, ... Annals of oncology 27 (12), 2275-2283, 2016 | 144 | 2016 |
| Prediction of intracellular exposure bridges the gap between target-and cell-based drug discovery A Mateus, LJ Gordon, GJ Wayne, H Almqvist, H Axelsson, ... Proceedings of the National Academy of Sciences 114 (30), E6231-E6239, 2017 | 90 | 2017 |
| NAMPT is the cellular target of STF-31-like small-molecule probes DJ Adams, D Ito, MG Rees, B Seashore-Ludlow, X Puyang, AH Ramos, ... ACS chemical biology 9 (10), 2247-2254, 2014 | 82 | 2014 |
| Enantioselective Synthesis of anti-β-Hydroxy-α-amido Esters via Transfer Hydrogenation B Seashore-Ludlow, P Villo, C Hacker, P Somfai Organic Letters 12 (22), 5274-5277, 2010 | 72 | 2010 |
| Domino carbopalladation–cross-coupling for the synthesis of 3, 3-disubstituted oxindoles B Seashore-Ludlow, P Somfai Organic letters 14 (15), 3858-3861, 2012 | 69 | 2012 |
| Targeting CDK 2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors A Azimi, S Caramuta, B Seashore‐Ludlow, J Boström, JL Robinson, ... Molecular systems biology 14 (3), e7858, 2018 | 67 | 2018 |
| Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells L Johannessen, TB Sundberg, DJ O'Connell, R Kolde, J Berstler, ... Nature chemical biology 13 (10), 1102-1108, 2017 | 67 | 2017 |
| DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets AR Hanaford, TC Archer, A Price, UD Kahlert, J Maciaczyk, G Nikkhah, ... Clinical Cancer Research 22 (15), 3903-3914, 2016 | 65 | 2016 |
| Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis K Brunner, S Maric, RS Reshma, H Almqvist, B Seashore-Ludlow, ... Journal of Medicinal Chemistry 59 (14), 6848-6859, 2016 | 64 | 2016 |
| Asymmetric Transfer Hydrogenation Coupled with Dynamic Kinetic Resolution in Water: Synthesis of anti-β-Hydroxy-α-amino Acid Derivatives B Seashore-Ludlow, F Saint-Dizier, P Somfai Organic letters 14 (24), 6334-6337, 2012 | 59 | 2012 |
| A general enantioselective route to the chamigrene natural product family DE White, IC Stewart, BA Seashore-Ludlow, RH Grubbs, BM Stoltz Tetrahedron 66 (26), 4668-4686, 2010 | 58 | 2010 |
| Discovery of a small-molecule probe for V-ATPase function LN Aldrich, SY Kuo, AB Castoreno, G Goel, P Kuballa, MG Rees, ... Journal of the American chemical society 137 (16), 5563-5568, 2015 | 53 | 2015 |
| Enantioselective Synthesis of anti‐β‐Hydroxy‐α‐Amido Esters by Asymmetric Transfer Hydrogenation in Emulsions B Seashore‐Ludlow, P Villo, P Somfai Chemistry–A European Journal 18 (23), 7219-7223, 2012 | 49 | 2012 |
| FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis SP Turunen, P von Nandelstadh, T Öhman, E Gucciardo, ... Cell Death & Differentiation 26 (12), 2577-2593, 2019 | 46 | 2019 |
| Domino Carbopalladation− Carbonylation: Generating Quaternary Stereocenters while Controlling β-Hydride Elimination B Seashore-Ludlow, P Somfai Organic Letters 12 (17), 3732-3735, 2010 | 42 | 2010 |