Rob van der Heijden

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Robert Verpoorteprofessor of plant cell biotechnology and pharmacognosy, Leiden UniversityVerified email at chem.leidenuniv.nl
Thomas HankemeierProfessor of Analytical Biosciences, Leiden UniversityVerified email at lacdr.leidenuniv.nl
Guowang XuDalian Institute of Chemical Physics, Chinese Academy of SciencesVerified email at dicp.ac.cn
Paulo Roberto H. MorenoInstituto de Química, Universidade de São PauloVerified email at iq.usp.br
Jan SchripsemaUniversidade Estadual do Norte FluminenseVerified email at uenf.br
Teris A. van BeekLecturer Natural Products Chemistry, Wageningen UniversityVerified email at wur.nl
Kornkanok IngkaninanProfessor. Faculty of Pharmaceutical Sciences, Naresuan UniversityVerified email at nu.ac.th
Ana C. Ramos ValdiviaCentro de Investigación y de Estudios Avanzados (CINVESTAV),MexicoVerified email at cinvestav.mx
Giancarlo PasqualiFederal University of Rio Grande do SulVerified email at cbiot.ufrgs.br
Louis HavekesTNO Metabolic Health Research and Prof. Leiden University Medical Center, Leiden, the NetherlandsVerified email at tno.nl
Walter M. van GulikDelft University of TechnologyVerified email at tudelft.nl
Renger WitkampProfessor of Nutritional BiologyVerified email at wur.nl
Marco GaspariFull professor of Analytical Chemistry, Magna Graecia University of CatanzaroVerified email at unicz.it
Rob VreekenAssociate Professor at M4I & Head Discovery & Exploratory BioAnalysis at Janssen R&DVerified email at its.jnj.com
Jeroen DeGrootSenior Director, Charles River LaboratoriesVerified email at crl.com
Jurre KamphorstVP of MS Technology & BiomarkersVerified email at myolaris.com
Norma PaniegoResearcher at Instituto Nacional Tecnologia Agropecuaria & CONICETVerified email at inta.gob.ar
Wim JiskootLeiden University, Coriolis PharmaVerified email at lacdr.leidenuniv.nl
Georgios TheodoridisProfessor, Dept. Chem. BIOMIC AUTh, ThetaBiomarkers, CIRI, Aristotle University of ThessalonikiVerified email at chem.auth.gr
Matej OrešičProfessor of Medicine (Systems Medicine), Örebro University & University of TurkuVerified email at oru.se

Rob van der Heijden

Leiden

Verified email at biology.leidenuniv.nl

PLANT BIOTECHNOLOGY ANALYTICAL CHEMISTRY


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The Catharanthus alkaloids: pharmacognosy and biotechnology DI Jacobs, W Snoeijer, D Hallard, R Verpoorte Current medicinal chemistry 11 (5), 607-628, 2004	1007	2004
Geraniol 10‐hydroxylase1, a cytochrome P450 enzyme involved in terpenoid indole alkaloid biosynthesis G Collu, N Unver, AMG Peltenburg-Looman, R van der Heijden, ... FEBS letters 508 (2), 215-220, 2001	411	2001
Metabolomics in the context of systems biology: bridging traditional Chinese medicine and molecular pharmacology M Wang, RJ Lamers, HA Korthout, JH van Nesselrooij, RF Witkamp, ... Phytother Res 19, 173-182, 2005	406	2005
Metabolic engineering of plant secondary metabolite pathways for the production of fine chemicals R Verpoorte, R van der Heijden, HJG Ten Hoopen, J Memelink Biotechnology letters 21, 467-479, 1999	404	1999
The role of analytical sciences in medical systems biology J van der Greef, P Stroobant, R van der Heijden Current opinion in chemical biology 8 (5), 559-565, 2004	336	2004
Engineering the plant cell factory for secondary metabolite production R Verpoorte, R van der Heijden, J Memelink Transgenic research 9, 323-343, 2000	305	2000
Cell and tissue cultures of Catharanthus roseus: A literature survey: II. Updating from 1988 to 1993 PRH Moreno, R van der Heijden, R Verpoorte Plant cell, tissue and organ culture 42, 1-25, 1995	305	1995
LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery [S] J van Smeden, L Hoppel, R van der Heijden, T Hankemeier, RJ Vreeken, ... Journal of lipid research 52 (6), 1211-1221, 2011	303	2011
Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus C Canel, MI Lopes-Cardoso, S Whitmer, L van der Fits, G Pasquali, ... Planta 205, 414-419, 1998	288	1998
Analytical strategies in lipidomics and applications in disease biomarker discovery C Hu, R van der Heijden, M Wang, J van der Greef, T Hankemeier, G Xu Journal of Chromatography B 877 (26), 2836-2846, 2009	280	2009
High-performance liquid chromatography with on-line coupled UV, mass spectrometric and biochemical detection for identification of acetylcholinesterase inhibitors from natural … K Ingkaninan, CM De Best, R Van Der Heijden, AJP Hofte, B Karabatak, ... Journal of Chromatography A 872 (1-2), 61-73, 2000	270	2000
The iridoid glucoside secologanin is derived from the novel triose phosphate/pyruvate pathway in a Catharanthus roseus cell culture A Contin, R van der Heijden, AWM Lefeber, R Verpoorte FEBS letters 434 (3), 413-416, 1998	235	1998
Molecular cloning and analysis of strictosidine β-D-glucosidase, an enzyme in terpenoid indole alkaloid biosynthesis in Catharanthus roseus A Geerlings, MML Ibanez, J Memelink, R van der Heijden, R Verpoorte Journal of Biological Chemistry 275 (5), 3051-3056, 2000	225	2000
Isopentenyl diphosphate isomerase: a core enzyme in isoprenoid biosynthesis. A review of its biochemistry and function AC Ramos-Valdivia, R van der Heijden, R Verpoorte Natural product reports 14 (6), 591-603, 1997	219	1997
RPLC-ion-trap-FTMS method for lipid profiling of plasma: method validation and application to p53 mutant mouse model C Hu, J Van Dommelen, R Van Der Heijden, G Spijksma, TH Reijmers, ... Journal of proteome research 7 (11), 4982-4991, 2008	214	2008
Cell and tissue cultures ofCatharanthus roseus (L.) G. Don: a literature survey R Van Der Heijden, R Verpoorte, HJG Ten Hoopen Plant cell, tissue and organ culture 18, 231-280, 1989	194	1989
Discovery of early-stage biomarkers for diabetic kidney disease using ms-based metabolomics (FinnDiane study) FM Van der Kloet, FWA Tempels, N Ismail, R Van der Heijden, PT Kasper, ... Metabolomics 8, 109-119, 2012	190	2012
Plant cell biotechnology for the production of alkaloids: present status and prospects R Verpoorte, R Van der Heijden, J Schripsema, JHC Hoge, ... Journal of Natural products 56 (2), 186-207, 1993	187	1993
Biosynthesis of anthraquinones in cell cultures of the Rubiaceae YS Han, R Van der Heijden, R Verpoorte Plant Cell, Tissue and Organ Culture 67, 201-220, 2001	184	2001
Effect of terpenoid precursor feeding and elicitation on formation of indole alkaloids in cell suspension cultures of Catharanthus roseus PRH Moreno, R Van der Heijden, R Verpoorte Plant Cell Reports 12, 702-705, 1993	183	1993

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