| A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals Y Wang, K Zhou, G Huang, C Hensley, X Huang, X Ma, T Zhao, BD Sumer, ... Nature materials 13 (2), 204-212, 2014 | 756 | 2014 |
| Non‐viral CRISPR/Cas gene editing in vitro and in vivo enabled by synthetic nanoparticle co‐delivery of Cas9 mRNA and sgRNA JB Miller, S Zhang, P Kos, H Xiong, K Zhou, SS Perelman, H Zhu, ... Angewandte Chemie 129 (4), 1079-1083, 2017 | 600 | 2017 |
| Tunable, ultrasensitive pH‐responsive nanoparticles targeting specific endocytic organelles in living cells K Zhou, Y Wang, X Huang, K Luby‐Phelps, BD Sumer, J Gao Angewandte Chemie International Edition 50 (27), 6109-6114, 2011 | 561 | 2011 |
| Multicolored pH-tunable and activatable fluorescence nanoplatform responsive to physiologic pH stimuli K Zhou, H Liu, S Zhang, X Huang, Y Wang, G Huang, BD Sumer, J Gao Journal of the American Chemical Society 134 (18), 7803-7811, 2012 | 350 | 2012 |
| Dendrimer‐based lipid nanoparticles deliver therapeutic FAH mRNA to normalize liver function and extend survival in a mouse model of hepatorenal tyrosinemia type I Q Cheng, T Wei, Y Jia, L Farbiak, K Zhou, S Zhang, Y Wei, H Zhu, ... Advanced materials 30 (52), 1805308, 2018 | 202 | 2018 |
| The polyploid state plays a tumor-suppressive role in the liver S Zhang, K Zhou, X Luo, L Li, HC Tu, A Sehgal, LH Nguyen, Y Zhang, ... Developmental cell 44 (4), 447-459. e5, 2018 | 190 | 2018 |
| Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model K Zhou, LH Nguyen, JB Miller, Y Yan, P Kos, H Xiong, L Li, J Hao, ... Proceedings of the National Academy of Sciences 113 (3), 520-525, 2016 | 174 | 2016 |
| The coil-to-globule-to-coil transition of linear polymer chains in dilute aqueous solutions: effect of intrachain hydrogen bonding K Zhou, Y Lu, J Li, L Shen, G Zhang, Z Xie, C Wu Macromolecules 41 (22), 8927-8931, 2008 | 118 | 2008 |
| Knockdown of anillin actin binding protein blocks cytokinesis in hepatocytes and reduces liver tumor development in mice without affecting regeneration S Zhang, LH Nguyen, K Zhou, HC Tu, A Sehgal, I Nassour, L Li, P Gopal, ... Gastroenterology 154 (5), 1421-1434, 2018 | 114 | 2018 |
| Tumor-activated water-soluble photosensitizers for near-infrared photodynamic cancer therapy H Xiong, K Zhou, Y Yan, JB Miller, DJ Siegwart ACS applied materials & interfaces 10 (19), 16335-16343, 2018 | 107 | 2018 |
| Rapid synthesis of a lipocationic polyester library via ring-opening polymerization of functional valerolactones for efficacious siRNA delivery J Hao, P Kos, K Zhou, JB Miller, L Xue, Y Yan, H Xiong, S Elkassih, ... Journal of the American Chemical Society 137 (29), 9206-9209, 2015 | 104 | 2015 |
| Origin of hysteresis observed in association and dissociation of polymer chains in water Y Lu, K Zhou, Y Ding, G Zhang, C Wu Physical Chemistry Chemical Physics 12 (13), 3188-3194, 2010 | 104 | 2010 |
| Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti–PD-L1 to eliminate melanoma in mice Y Wang, L Su, MD Morin, BT Jones, Y Mifune, H Shi, K Wang, X Zhan, ... Proceedings of the National Academy of Sciences 115 (37), E8698-E8706, 2018 | 103 | 2018 |
| Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells Y Yan, L Liu, H Xiong, JB Miller, K Zhou, P Kos, KE Huffman, S Elkassih, ... Proceedings of the National Academy of Sciences 113 (39), E5702-E5710, 2016 | 83 | 2016 |
| Re-examination of Dynamics of Polyeletrolytes in Salt-Free Dilute Solutions by Designing and Using a Novel Neutral− Charged− Neutral Reversible Polymer K Zhou, J Li, Y Lu, G Zhang, Z Xie, C Wu Macromolecules 42 (18), 7146-7154, 2009 | 77 | 2009 |
| High‐contrast fluorescence detection of metastatic breast cancer including bone and liver micrometastases via size‐controlled pH‐Activatable water‐soluble probes H Xiong, H Zuo, Y Yan, G Occhialini, K Zhou, Y Wan, DJ Siegwart Advanced Materials 29 (29), 1700131, 2017 | 72 | 2017 |
| Precise let-7 expression levels balance organ regeneration against tumor suppression L Wu, LH Nguyen, K Zhou, TY de Soysa, L Li, JB Miller, J Tian, J Locker, ... Elife 4, e09431, 2015 | 70 | 2015 |
| Aerosol delivery of stabilized polyester-siRNA nanoparticles to silence gene expression in orthotopic lung tumors Y Yan, K Zhou, H Xiong, JB Miller, EA Motea, DA Boothman, L Liu, ... Biomaterials 118, 84-93, 2017 | 68 | 2017 |
| Activatable water-soluble probes enhance tumor imaging by responding to dysregulated pH and exhibiting high tumor-to-liver fluorescence emission contrast H Xiong, P Kos, Y Yan, K Zhou, JB Miller, S Elkassih, DJ Siegwart Bioconjugate chemistry 27 (7), 1737-1744, 2016 | 62 | 2016 |
| Chaotropic‐anion‐induced supramolecular self‐assembly of ionic polymeric micelles Y Li, Y Wang, G Huang, X Ma, K Zhou, J Gao Angewandte Chemie 126 (31), 8212-8216, 2014 | 52 | 2014 |
Daniel SiegwartProfessor, University of Texas Southwestern Medical CenterVerified email at utsouthwestern.edu