| Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome C Gross, M Nakamoto, X Yao, CB Chan, SY Yim, K Ye, ST Warren, ... Journal of Neuroscience 30 (32), 10624-10638, 2010 | 280 | 2010 |
| 7, 8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer’s disease Z Zhang, X Liu, JP Schroeder, CB Chan, M Song, SP Yu, D Weinshenker, ... Neuropsychopharmacology 39 (3), 638-650, 2014 | 253 | 2014 |
| A synthetic 7, 8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect X Liu, CB Chan, SW Jang, S Pradoldej, J Huang, K He, LH Phun, ... Journal of medicinal chemistry 53 (23), 8274-8286, 2010 | 235 | 2010 |
| The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor PK Leung, KBS Chow, PN Lau, KM Chu, CB Chan, CHK Cheng, H Wise Cellular signalling 19 (5), 1011-1022, 2007 | 216 | 2007 |
| Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation X Wang, P Yue, CB Chan, K Ye, T Ueda, R Watanabe-Fukunaga, ... Molecular and cellular biology, 2007 | 202 | 2007 |
| Sex differences in brain‐derived neurotrophic factor signaling and functions CB Chan, K Ye Journal of neuroscience research 95 (1-2), 328-335, 2017 | 198 | 2017 |
| The co-existence of two growth hormone receptors in teleost fish and their differential signal transduction, tissue distribution and hormonal regulation of expression in seabream B Jiao, X Huang, CB Chan, L Zhang, D Wang, CHK Cheng Journal of Molecular Endocrinology 36 (1), 23-40, 2006 | 195 | 2006 |
| 7, 8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-implicated human disorders C Liu, CB Chan, K Ye Translational neurodegeneration 5, 1-9, 2016 | 194 | 2016 |
| Identification and functional characterization of two alternatively spliced growth hormone secretagogue receptor transcripts from the pituitary of black seabream Acanthopagrus … CB Chan, CHK Cheng Molecular and cellular endocrinology 214 (1-2), 81-95, 2004 | 185 | 2004 |
| Amitriptyline is a TrkA and TrkB receptor agonist that promotes TrkA/TrkB heterodimerization and has potent neurotrophic activity SW Jang, X Liu, CB Chan, D Weinshenker, RA Hall, G Xiao, K Ye Chemistry & biology 16 (6), 644-656, 2009 | 168 | 2009 |
| Deoxygedunin, a natural product with potent neurotrophic activity in mice SW Jang, X Liu, CB Chan, SA France, I Sayeed, W Tang, X Lin, G Xiao, ... PloS one 5 (7), e11528, 2010 | 144 | 2010 |
| Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B X Tang, SW Jang, M Okada, CB Chan, Y Feng, Y Liu, SW Luo, Y Hong, ... Nature Cell Biology 10 (6), 698-706, 2008 | 135 | 2008 |
| Biochemical and biophysical investigation of the brain-derived neurotrophic factor mimetic 7, 8-dihydroxyflavone in the binding and activation of the TrkB receptor X Liu, O Obianyo, CB Chan, J Huang, S Xue, JJ Yang, F Zeng, ... Journal of Biological Chemistry 289 (40), 27571-27584, 2014 | 123 | 2014 |
| Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome C Gross, CW Chang, SM Kelly, A Bhattacharya, SMJ McBride, ... Cell reports 11 (5), 727-736, 2015 | 117 | 2015 |
| Cells of the anterior pituitary CM Yeung, CB Chan, PS Leung, CHK Cheng The international journal of biochemistry & cell biology 38 (9), 1441-1449, 2006 | 106 | 2006 |
| Seabream growth hormone receptor: molecular cloning and functional studies of the full-length cDNA, and tissue expression of two alternatively spliced forms LY Dicky, CL Margaret, CB Chan, L Deng, WM Zhang, HR Lin, ... Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1625 (1 …, 2003 | 95 | 2003 |
| Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome CB Chan, M Abe, N Hashimoto, C Hao, IR Williams, X Liu, S Nakao, ... Proceedings of the National Academy of Sciences 106 (2), 468-473, 2009 | 85 | 2009 |
| Activation of muscular TrkB by its small molecular agonist 7, 8-dihydroxyflavone sex-dependently regulates energy metabolism in diet-induced obese mice CB Chan, MCL Tse, X Liu, S Zhang, R Schmidt, R Otten, L Liu, K Ye Chemistry & biology 22 (3), 355-368, 2015 | 81 | 2015 |
| Seabream ghrelin: cDNA cloning, genomic organization and promoter studies CM Yeung, CB Chan, NYS Woo, CHK Cheng Journal of Endocrinology 189 (2), 365-379, 2006 | 79 | 2006 |
| Muscle-generated BDNF is a sexually dimorphic myokine that controls metabolic flexibility X Yang, D Brobst, WS Chan, MCL Tse, O Herlea-Pana, P Ahuja, X Bi, ... Science signaling 12 (594), eaau1468, 2019 | 76 | 2019 |
Qi QiChina Pharmaceutical university, West Virginia University, Emory University，Jinan UniversityVerified email at jnu.edu.cn