| Inhibition and induction of human cytochrome P450 enzymes: current status O Pelkonen, M Turpeinen, J Hakkola, P Honkakoski, J Hukkanen, ... Archives of toxicology 82, 667-715, 2008 | 731 | 2008 |
| Expression and regulation of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in human lung J Hukkanen, O Pelkonen, J Hakkola, H Raunio Critical reviews in toxicology 32 (5), 391-411, 2002 | 425 | 2002 |
| Inhibition and induction of CYP enzymes in humans: an update J Hakkola, J Hukkanen, M Turpeinen, O Pelkonen Archives of Toxicology 94 (11), 3671-3722, 2020 | 327 | 2020 |
| Xenobiotic-metabolizing cytochrome P450 enzymes in the human feto-placental unit: role in intrauterine toxicity J Hakkola, O Pelkonen, M Pasanen, H Raunio Critical reviews in toxicology 28 (1), 35-72, 1998 | 282 | 1998 |
| Expression of xenobiotic-metabolizing cytochrome P450 forms in human full-term placenta J Hakkola, M Pasanen, J Hukkanen, O Pelkonen, J Mäenpää, ... Biochemical pharmacology 51 (4), 403-411, 1996 | 269 | 1996 |
| Expression of CYP1B1 in human adult and fetal tissues and differential inducibility of CYP1B1 and CYP1A1 by Ah receptor ligands in human placenta and cultured cells. J Hakkola, M Pasanen, O Pelkonen, J Hukkanen, S Evisalmi, S Anttila, ... Carcinogenesis 18 (2), 391-397, 1997 | 266 | 1997 |
| Expression of xenobiotic-metabolizing cytochrome P450 forms in human adult and fetal liver J Hakkola, M Pasanen, R Purkunen, S Saarikoski, O Pelkonen, ... Biochemical pharmacology 48 (1), 59-64, 1994 | 237 | 1994 |
| Detection of cytochrome P450 gene expression in human placenta in first trimester of pregnancy J Hakkola, H Raunio, R Purkunen, O Pelkonen, S Saarikoski, T Cresteil, ... Biochemical pharmacology 52 (2), 379-383, 1996 | 219 | 1996 |
| Expression and localization of CYP3A4 and CYP3A5 in human lung. S Anttila, J Hukkanen, J Hakkola, T Stjernvall, P Beaune, RJ Edwards, ... American journal of respiratory cell and molecular biology 16 (3), 242-249, 1997 | 210 | 1997 |
| Induction and regulation of xenobiotic-metabolizing cytochrome P450s in the human A549 lung adenocarcinoma cell line J Hukkanen, A Lassila, K Paivarinta, S Valanne, S Sarpo, J Hakkola, ... American journal of respiratory cell and molecular biology 22 (3), 360-366, 2000 | 209 | 2000 |
| Expression of CYP2A genes in human liver and extrahepatic tissues S Koskela, J Hakkola, J Hukkanen, O Pelkonen, M Sorri, A Saranen, ... Biochemical pharmacology 57 (12), 1407-1413, 1999 | 200 | 1999 |
| Functional role of P‐glycoprotein in the human blood‐placental barrier M Mölsä, T Heikkinen, J Hakkola, K Hakala, O Wallerman, M Wadelius, ... Clinical Pharmacology & Therapeutics 78 (2), 123-131, 2005 | 174 | 2005 |
| Methylation of cytochrome P4501A1 promoter in the lung is associated with tobacco smoking S Anttila, J Hakkola, P Tuominen, E Elovaara, K Husgafvel-Pursiainen, ... Cancer research 63 (24), 8623-8628, 2003 | 162 | 2003 |
| Developmental expression of cytochrome P450 enzymes in human liver J Hakkola, E Tanaka, O Pelkonen Pharmacology & toxicology 82 (5), 209-217, 1998 | 156 | 1998 |
| SIRT5 is under the control of PGC‐1α and AMPK and is involved in regulation of mitochondrial energy metabolism M Buler, SM Aatsinki, V Izzi, J Uusimaa, J Hakkola The FASEB Journal 28 (7), 3225-3237, 2014 | 151 | 2014 |
| Expression of xenobiotic-metabolizing CYPs in human pulmonary tissue H Raunio, J Hakkola, J Hukkanen, A Lassila, K Päivärinta, O Pelkonen, ... Experimental and Toxicologic Pathology 51 (4-5), 412-417, 1999 | 136 | 1999 |
| Regulation of CYP3A5 by glucocorticoids and cigarette smoke in human lung-derived cells J Hukkanen, T Väisänen, A Lassila, R Piipari, S Anttila, O Pelkonen, ... Journal of Pharmacology and Experimental Therapeutics 304 (2), 745-752, 2003 | 129 | 2003 |
| Expression of CYP1A1, CYP1B1 and CYP3A, and polycyclic aromatic hydrocarbon‐DNA adduct formation in bronchoalveolar macrophages of smokers and non‐smokers R Piipari, K Savela, T Nurminen, J Hukkanen, H Raunio, J Hakkola, ... International journal of cancer 86 (5), 610-616, 2000 | 125 | 2000 |
| Regulation of hepatic energy metabolism by the nuclear receptor PXR J Hakkola, J Rysä, J Hukkanen Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1859 (9 …, 2016 | 118 | 2016 |
| Characterization of human cytochrome P450 induction by pesticides K Abass, V Lämsä, P Reponen, J Küblbeck, P Honkakoski, S Mattila, ... Toxicology 294 (1), 17-26, 2012 | 109 | 2012 |
Olavi PelkoneneProfessor of Pharmacology, University of OuluVerified email at oulu.fi