| Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery L Tang, Y Zheng, MB Melo, L Mabardi, AP Castaño, YQ Xie, N Li, ... Nature biotechnology 36 (8), 707-716, 2018 | 583 | 2018 |
| Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity Y Guo*, YQ Xie*, M Gao, Y Zhao, F Franco, M Wenes, I Siddiqui, ... Nature Immunology, 1-11, 2021 | 276 | 2021 |
| Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy K Lei, A Kurum, M Kaynak, L Bonati, Y Han, V Cencen, M Gao, YQ Xie, ... Nature biomedical engineering 5 (12), 1411-1425, 2021 | 153 | 2021 |
| Redox-responsive interleukin-2 nanogel specifically and safely promotes the proliferation and memory precursor differentiation of tumor-reactive T-cells YQ Xie, H Arik, L Wei, Y Zheng, H Suh, DJ Irvine, L Tang Biomaterials science 7 (4), 1345-1357, 2019 | 80 | 2019 |
| IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases Y Zhao, J Chen, M Andreatta, B Feng, YQ Xie, M Wenes, Y Wang, M Gao, ... Nature Biotechnology, 1-12, 2024 | 70 | 2024 |
| Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion Q Zeng, S Saghafinia, A Chryplewicz, N Fournier, L Christe, YQ Xie, ... Science 378 (6621), eabl7207, 2022 | 52 | 2022 |
| A manganese phosphate nanocluster activates the cGAS‐STING pathway for enhanced cancer immunotherapy M Gao, YQ Xie, K Lei, Y Zhao, A Kurum, S Van Herck, Y Guo, X Hu, ... Advanced Therapeutics, 2100065, 2021 | 49 | 2021 |
| Immunoengineering with biomaterials for enhanced cancer immunotherapy YQ Xie, L Wei, L Tang Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 10 (4 …, 2018 | 47 | 2018 |
| Epigenetics and primary biliary cirrhosis: a comprehensive review and implications for autoimmunity YQ Xie, HD Ma, ZX Lian Clinical reviews in allergy & immunology 50, 390-403, 2016 | 42 | 2016 |
| Block of both TGF-β and IL-2 signaling impedes Neurophilin-1+ regulatory T cell and follicular regulatory T cell development L Li, SH Yang, Y Yao, YQ Xie, YQ Yang, YH Wang, XY Yin, HD Ma, ... Cell Death & Disease 7 (10), e2439-e2439, 2016 | 38 | 2016 |
| Switchable immune modulator for tumor-specific activation of anticancer immunity Y Zhao, YQ Xie, S Van Herck, S Nassiri, M Gao, Y Guo, L Tang Science advances 7 (37), eabg7291, 2021 | 37 | 2021 |
| The type 2 cytokine Fc–IL-4 revitalizes exhausted CD8+ T cells against cancer B Feng, Z Bai, X Zhou, Y Zhao, YQ Xie, X Huang, Y Liu, T Enbar, R Li, ... Nature 634 (8034), 712-720, 2024 | 17 | 2024 |
| IFN-γ–STAT1–iNOS induces myeloid progenitors to acquire immunosuppressive activity SH Yang, L Li, YQ Xie, Y Yao, CY Gao, LH Liao, HD Ma, ME Gershwin, ... Frontiers in immunology 8, 1192, 2017 | 16 | 2017 |
| CD8+ T cells and IFN-γ induce autoimmune myelofibrosis in mice Y Yao, L Li, SH Yang, CY Gao, LH Liao, YQ Xie, XY Yin, YQ Yang, YY Fei, ... Journal of Autoimmunity 89, 101-111, 2018 | 12 | 2018 |
| Ultrashort‐Peptide‐Responsive Gene Switches for Regulation of Therapeutic Protein Expression in Mammalian Cells J Huang, S Xue, YQ Xie, AP Teixeira, M Fussenegger Advanced Science, 2309411, 2024 | 4 | 2024 |
| IL-10/Fc fusion proteins useful as enhancers of immunotherapies Y Guo, L Tang, YQ Xie EP Patent WO/2021/053,134, 2021 | 1 | 2021 |
| Engineering T Cell Trafficking and Function for Enhanced Cancer Immunotherapy Y Xie EPFL, 2022 | | 2022 |
| CD8+ T cell derived IFN-γ induces autoimmune myelofibrosis in mice Y Yao, L Li, SH Yang, CY Gao, LH Liao, YQ Xie, XY Yin, YQ Yang, ... 第十二届全国免疫学学术大会壁报交流集, 2017 | | 2017 |
| TGF-β and IL-2 signaling are both required for generating stable thymus regulatory T cells L Li, Y Yao, YQ Xie, ZX Lian 第十届全国免疫学学术大会分会场交流报告 (一), 2015 | | 2015 |
| IFN-γ and CD8+ T cells contribute to hematopoietic system dysregulation in p40 (-/-) interleukin-2Rα (-/-) mice Y Yao, L Li, XY Yin, YQ Xie 第十届全国免疫学学术大会汇编, 2015 | | 2015 |
Li Tang (EPFL)Associate Professor, École Polytechnique Fédérale de LausanneVerified email at epfl.ch
