A framework for advancing our understanding of cancer-associated fibroblasts E Sahai, I Astsaturov, E Cukierman, DG DeNardo, M Egeblad, RM Evans, ... Nature Reviews Cancer 20 (3), 174-186, 2020 | 3029 | 2020 |
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4 R Scherz‐Shouval, E Shvets, E Fass, H Shorer, L Gil, Z Elazar The EMBO journal 26 (7), 1749-1760, 2007 | 2436 | 2007 |
Regulation of autophagy by ROS: physiology and pathology R Scherz-Shouval, Z Elazar Trends in biochemical sciences 36 (1), 30-38, 2011 | 1417 | 2011 |
ROS, mitochondria and the regulation of autophagy R Scherz-Shouval, Z Elazar Trends in cell biology 17 (9), 422-427, 2007 | 1129 | 2007 |
Extracellular vesicle and particle biomarkers define multiple human cancers A Hoshino, HS Kim, L Bojmar, KE Gyan, M Cioffi, J Hernandez, ... Cell 182 (4), 1044-1061. e18, 2020 | 995 | 2020 |
The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy R Scherz-Shouval, S Santagata, ML Mendillo, LM Sholl, I Ben-Aharon, ... Cell 158 (3), 564-578, 2014 | 409 | 2014 |
Fitness trade-offs restrict the evolution of resistance to amphotericin B BM Vincent, AK Lancaster, R Scherz-Shouval, L Whitesell, S Lindquist PLoS biology 11 (10), e1001692, 2013 | 364 | 2013 |
Cancer-associated fibroblasts in the single-cell era D Lavie, A Ben-Shmuel, N Erez, R Scherz-Shouval Nature cancer 3 (7), 793-807, 2022 | 308 | 2022 |
p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation R Scherz-Shouval, H Weidberg, C Gonen, S Wilder, Z Elazar, M Oren Proceedings of the National Academy of Sciences 107 (43), 18511-18516, 2010 | 269 | 2010 |
Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4+ and PDPN+ CAFs to clinical outcome G Friedman, O Levi-Galibov, E David, C Bornstein, A Giladi, M Dadiani, ... Nature Cancer 1 (7), 692-708, 2020 | 247 | 2020 |
Oxidation as a post-translational modification that regulates autophagy R Scherz-Shouval, E Shvets, Z Elazar Autophagy 3 (4), 371-373, 2007 | 203 | 2007 |
Impact of TP53 Genomic Alterations in Large B-Cell Lymphoma Treated With CD19-Chimeric Antigen Receptor T-Cell Therapy R Shouval, A Alarcon Tomas, JA Fein, JR Flynn, E Markovits, S Mayer, ... Journal of clinical oncology 40 (4), 369-381, 2022 | 114 | 2022 |
The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A R Scherz-Shouval, Y Sagiv, H Shorer, Z Elazar Journal of Biological Chemistry 278 (16), 14053-14058, 2003 | 95 | 2003 |
Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution D Dierks, MA Garcia-Campos, A Uzonyi, M Safra, S Edelheit, A Rossi, ... Nature methods 18 (9), 1060-1067, 2021 | 85 | 2021 |
Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer O Levi-Galibov, H Lavon, R Wassermann-Dozorets, M Pevsner-Fischer, ... Nature communications 11 (1), 6245, 2020 | 85 | 2020 |
The tumor microenvironment shows a hierarchy of cell-cell interactions dominated by fibroblasts S Mayer, T Milo, A Isaacson, C Halperin, S Miyara, Y Stein, C Lior, ... Nature communications 14 (1), 5810, 2023 | 81 | 2023 |
Cancer-associated fibroblasts promote aggressive gastric cancer phenotypes via heat shock factor 1–mediated secretion of extracellular vesicles N Grunberg, M Pevsner-Fischer, T Goshen-Lago, J Diment, Y Stein, ... Cancer research 81 (7), 1639-1653, 2021 | 79 | 2021 |
Structure–activity relationships for withanolides as inducers of the cellular heat-shock response EMK Wijeratne, YM Xu, R Scherz-Shouval, MT Marron, DD Rocha, MX Liu, ... Journal of medicinal chemistry 57 (7), 2851-2863, 2014 | 79 | 2014 |
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4 R Scherz‐Shouval, E Shvets, E Fass, H Shorer, L Gil, Z Elazar The EMBO journal 38 (10), e101812, 2019 | 65 | 2019 |
T cells promote metastasis by regulating extracellular matrix remodeling following chemotherapy J Haj-Shomaly, A Vorontsova, T Barenholz-Cohen, O Levi-Galibov, ... Cancer research 82 (2), 278-291, 2022 | 58 | 2022 |