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Ruth Scherz-Shouval
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A framework for advancing our understanding of cancer-associated fibroblasts
E Sahai, I Astsaturov, E Cukierman, DG DeNardo, M Egeblad, RM Evans, ...
Nature Reviews Cancer 20 (3), 174-186, 2020
30292020
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
R Scherz‐Shouval, E Shvets, E Fass, H Shorer, L Gil, Z Elazar
The EMBO journal 26 (7), 1749-1760, 2007
24362007
Regulation of autophagy by ROS: physiology and pathology
R Scherz-Shouval, Z Elazar
Trends in biochemical sciences 36 (1), 30-38, 2011
14172011
ROS, mitochondria and the regulation of autophagy
R Scherz-Shouval, Z Elazar
Trends in cell biology 17 (9), 422-427, 2007
11292007
Extracellular vesicle and particle biomarkers define multiple human cancers
A Hoshino, HS Kim, L Bojmar, KE Gyan, M Cioffi, J Hernandez, ...
Cell 182 (4), 1044-1061. e18, 2020
9952020
The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy
R Scherz-Shouval, S Santagata, ML Mendillo, LM Sholl, I Ben-Aharon, ...
Cell 158 (3), 564-578, 2014
4092014
Fitness trade-offs restrict the evolution of resistance to amphotericin B
BM Vincent, AK Lancaster, R Scherz-Shouval, L Whitesell, S Lindquist
PLoS biology 11 (10), e1001692, 2013
3642013
Cancer-associated fibroblasts in the single-cell era
D Lavie, A Ben-Shmuel, N Erez, R Scherz-Shouval
Nature cancer 3 (7), 793-807, 2022
3082022
p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation
R Scherz-Shouval, H Weidberg, C Gonen, S Wilder, Z Elazar, M Oren
Proceedings of the National Academy of Sciences 107 (43), 18511-18516, 2010
2692010
Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4+ and PDPN+ CAFs to clinical outcome
G Friedman, O Levi-Galibov, E David, C Bornstein, A Giladi, M Dadiani, ...
Nature Cancer 1 (7), 692-708, 2020
2472020
Oxidation as a post-translational modification that regulates autophagy
R Scherz-Shouval, E Shvets, Z Elazar
Autophagy 3 (4), 371-373, 2007
2032007
Impact of TP53 Genomic Alterations in Large B-Cell Lymphoma Treated With CD19-Chimeric Antigen Receptor T-Cell Therapy
R Shouval, A Alarcon Tomas, JA Fein, JR Flynn, E Markovits, S Mayer, ...
Journal of clinical oncology 40 (4), 369-381, 2022
1142022
The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A
R Scherz-Shouval, Y Sagiv, H Shorer, Z Elazar
Journal of Biological Chemistry 278 (16), 14053-14058, 2003
952003
Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution
D Dierks, MA Garcia-Campos, A Uzonyi, M Safra, S Edelheit, A Rossi, ...
Nature methods 18 (9), 1060-1067, 2021
852021
Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer
O Levi-Galibov, H Lavon, R Wassermann-Dozorets, M Pevsner-Fischer, ...
Nature communications 11 (1), 6245, 2020
852020
The tumor microenvironment shows a hierarchy of cell-cell interactions dominated by fibroblasts
S Mayer, T Milo, A Isaacson, C Halperin, S Miyara, Y Stein, C Lior, ...
Nature communications 14 (1), 5810, 2023
812023
Cancer-associated fibroblasts promote aggressive gastric cancer phenotypes via heat shock factor 1–mediated secretion of extracellular vesicles
N Grunberg, M Pevsner-Fischer, T Goshen-Lago, J Diment, Y Stein, ...
Cancer research 81 (7), 1639-1653, 2021
792021
Structure–activity relationships for withanolides as inducers of the cellular heat-shock response
EMK Wijeratne, YM Xu, R Scherz-Shouval, MT Marron, DD Rocha, MX Liu, ...
Journal of medicinal chemistry 57 (7), 2851-2863, 2014
792014
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
R Scherz‐Shouval, E Shvets, E Fass, H Shorer, L Gil, Z Elazar
The EMBO journal 38 (10), e101812, 2019
652019
T cells promote metastasis by regulating extracellular matrix remodeling following chemotherapy
J Haj-Shomaly, A Vorontsova, T Barenholz-Cohen, O Levi-Galibov, ...
Cancer research 82 (2), 278-291, 2022
582022
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