Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions A Kirkeby, S Grealish, DA Wolf, J Nelander, J Wood, M Lundblad, ... Cell reports 1 (6), 703-714, 2012 | 786 | 2012 |
Generation of induced neurons via direct conversion in vivo O Torper, U Pfisterer, DA Wolf, M Pereira, S Lau, J Jakobsson, ... Proceedings of the National Academy of Sciences 110 (17), 7038-7043, 2013 | 508 | 2013 |
Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease S Grealish, E Diguet, A Kirkeby, B Mattsson, A Heuer, Y Bramoulle, ... Cell stem cell 15 (5), 653-665, 2014 | 496 | 2014 |
The future of stem cell therapies for Parkinson disease M Parmar, S Grealish, C Henchcliffe Nature Reviews Neuroscience 21 (2), 103-115, 2020 | 300 | 2020 |
Predictive markers guide differentiation to improve graft outcome in clinical translation of hESC-based therapy for Parkinson’s Disease A Kirkeby, S Nolbrant, K Tiklova, A Heuer, N Kee, T Cardoso, ... Cell Stem Cell 20 (1), 135-148, 2017 | 299 | 2017 |
In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry O Torper, DR Ottosson, M Pereira, S Lau, T Cardoso, S Grealish, ... Cell reports 12 (3), 474-481, 2015 | 216 | 2015 |
Characterisation of behavioural and neurodegenerative changes induced by intranigral 6‐hydroxydopamine lesions in a mouse model of Parkinson’s disease S Grealish, B Mattsson, P Draxler, A Björklund European Journal of Neuroscience 31 (12), 2266-2278, 2010 | 178 | 2010 |
The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson’s disease S Grealish, ME Jönsson, M Li, D Kirik, A Björklund, LH Thompson Brain 133 (2), 482-495, 2010 | 174 | 2010 |
Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli D Tornero, O Tsupykov, M Granmo, C Rodriguez, M Grønning-Hansen, ... Brain 140 (3), 692-706, 2017 | 153 | 2017 |
Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain LH Thompson, S Grealish, D Kirik, A Björklund European Journal of Neuroscience 30 (4), 625-638, 2009 | 145 | 2009 |
Monosynaptic tracing using modified rabies virus reveals early and extensive circuit integration of human embryonic stem cell-derived neurons S Grealish, A Heuer, T Cardoso, A Kirkeby, M Jönsson, J Johansson, ... Stem cell reports 4 (6), 975-983, 2015 | 105 | 2015 |
hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson’s Disease AF Adler, T Cardoso, S Nolbrant, B Mattsson, DB Hoban, U Jarl, ... Cell Reports 28 (13), 3462-3473. e5, 2019 | 92 | 2019 |
GDNF is not required for catecholaminergic neuron survival in vivo J Kopra, C Vilenius, S Grealish, MA Härma, K Varendi, J Lindholm, ... Nature neuroscience 18 (3), 319-322, 2015 | 76 | 2015 |
Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of parkinsonian rats T Cardoso, A Adler, B Mattsson, DB Hoban, S Nolbrant, ... Journal of Comparative Neurology, 2018 | 66 | 2018 |
Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain M Pereira, U Pfisterer, D Rylander, O Torper, S Lau, M Lundblad, ... Scientific reports 4, 6330, 2014 | 65 | 2014 |
IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells D Lehnen, S Barral, T Cardoso, S Grealish, A Heuer, A Smiyakin, ... Stem Cell Reports 9 (4), 1207-1220, 2017 | 59 | 2017 |
Unilateral axonal or terminal injection of 6-hydroxydopamine causes rapid-onset nigrostriatal degeneration and contralateral motor impairments in the rat S Grealish, L Xie, M Kelly, E Dowd Brain research bulletin 77 (5), 312-319, 2008 | 45 | 2008 |
Brain repair and reprogramming: the route to clinical translation S Grealish, J Drouin‐Ouellet, M Parmar Journal of Internal Medicine 280 (3), 265-275, 2016 | 31 | 2016 |
Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism D Rylander, V Bagetta, V Pendolino, E Zianni, S Grealish, F Gardoni, ... Proceedings of the National Academy of Sciences 110 (46), E4375-E4384, 2013 | 31 | 2013 |
Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases J Nelander, S Grealish, M Parmar Neuroreport 24 (18), 1025-1030, 2013 | 12 | 2013 |