A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4+ CD25+ Foxp3+ T cells B Hoechst, LA Ormandy, M Ballmaier, F Lehner, C Krüger, MP Manns, ... Gastroenterology 135 (1), 234-243, 2008 | 984 | 2008 |
Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor B Hoechst, T Voigtlaender, L Ormandy, J Gamrekelashvili, F Zhao, ... Hepatology 50 (3), 799-807, 2009 | 729 | 2009 |
Functional classification of memory CD8+ T cells by CX3CR1 expression JP Böttcher, M Beyer, F Meissner, Z Abdullah, J Sander, B Höchst, ... Nature communications 6 (1), 8306, 2015 | 294 | 2015 |
Plasticity of human Th17 cells and iTregs is orchestrated by different subsets of myeloid cells B Hoechst, J Gamrekelashvili, MP Manns, TF Greten, F Korangy Blood, The Journal of the American Society of Hematology 117 (24), 6532-6541, 2011 | 279 | 2011 |
S100A9 a new marker for monocytic human myeloid‐derived suppressor cells F Zhao, B Hoechst, A Duffy, J Gamrekelashvili, S Fioravanti, MP Manns, ... Immunology 136 (2), 176-183, 2012 | 254 | 2012 |
Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal T Baumann, A Dunkel, C Schmid, S Schmitt, M Hiltensperger, K Lohr, ... Nature immunology 21 (5), 555-566, 2020 | 215 | 2020 |
Kupffer cell-derived Tnf triggers cholangiocellular tumorigenesis through JNK due to chronic mitochondrial dysfunction and ROS D Yuan, S Huang, E Berger, L Liu, N Gross, F Heinzmann, M Ringelhan, ... Cancer cell 31 (6), 771-789. e6, 2017 | 198 | 2017 |
Low-dose cyclophosphamide treatment impairs regulatory T cells and unmasks AFP-specific CD4+ T-cell responses in patients with advanced HCC TF Greten, LA Ormandy, A Fikuart, B Höchst, S Henschen, M Hörning, ... Journal of immunotherapy 33 (2), 211-218, 2010 | 170 | 2010 |
Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in a CD44-dependent fashion B Höchst, FA Schildberg, P Sauerborn, YA Gäbel, H Gevensleben, ... Journal of hepatology 59 (3), 528-535, 2013 | 151 | 2013 |
Pancreatic premalignant lesions secrete tissue inhibitor of metalloproteinases-1, which activates hepatic stellate cells via CD63 signaling to create a premetastatic niche in … B Grünwald, V Harant, S Schaten, M Frühschütz, R Spallek, B Höchst, ... Gastroenterology 151 (5), 1011-1024. e7, 2016 | 121 | 2016 |
Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity B Knier, M Hiltensperger, C Sie, L Aly, G Lepennetier, T Engleitner, ... Nature immunology 19 (12), 1341-1351, 2018 | 108 | 2018 |
Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity JP Böttcher, O Schanz, D Wohlleber, Z Abdullah, S Debey-Pascher, ... Cell reports 3 (3), 779-795, 2013 | 96 | 2013 |
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses F Bayerl, P Meiser, S Donakonda, A Hirschberger, SB Lacher, AM Pedde, ... Immunity 56 (6), 1341-1358. e11, 2023 | 90 | 2023 |
Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance toward circulating carcinoembryonic antigen in mice B Höchst, FA Schildberg, J Böttcher, C Metzger, S Huss, A Türler, ... Hepatology 56 (5), 1924-1933, 2012 | 77 | 2012 |
Human CCR4+ CCR6+ Th17 cells suppress autologous CD8+ T cell responses F Zhao, B Hoechst, J Gamrekelashvili, LA Ormandy, T Voigtländer, ... The Journal of Immunology 188 (12), 6055-6062, 2012 | 75 | 2012 |
Differential induction of Ly6G and Ly6C positive myeloid derived suppressor cells in chronic kidney and liver inflammation and fibrosis B Höchst, J Mikulec, T Baccega, C Metzger, M Welz, J Peusquens, ... PloS one 10 (3), e0119662, 2015 | 62 | 2015 |
Immune responses in hepatocellular carcinoma F Korangy, B Höchst, MP Manns, TF Greten Digestive diseases 28 (1), 150-154, 2010 | 60 | 2010 |
The induction of human myeloid derived suppressor cells through hepatic stellate cells is dose-dependently inhibited by the tyrosine kinase inhibitors nilotinib, dasatinib and … A Heine, J Schilling, B Grünwald, A Krüger, H Gevensleben, SAE Held, ... Cancer Immunology, Immunotherapy 65, 273-282, 2016 | 46 | 2016 |
Age-related gliosis promotes central nervous system lymphoma through CCL19-mediated tumor cell retention T O'Connor, X Zhou, J Kosla, A Adili, MG Beccaria, E Kotsiliti, D Pfister, ... Cancer cell 36 (3), 250-267. e9, 2019 | 36 | 2019 |
Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression H Kalkavan, P Sharma, S Kasper, I Helfrich, AA Pandyra, A Gassa, ... Nature Communications 8 (1), 14447, 2017 | 32 | 2017 |