| The Hsp70/Hsp90 chaperone machinery in neurodegenerative diseases RE Lackie, A Maciejewski, VG Ostapchenko, J Marques-Lopes, WY Choy, ... Frontiers in neuroscience 11, 254, 2017 | 391 | 2017 |
| The α-helical C-terminal domain of full-length recombinant PrP converts to an in-register parallel β-sheet structure in PrP fibrils: evidence from solid state nuclear magnetic … R Tycko, R Savtchenko, VG Ostapchenko, N Makarava, IV Baskakov Biochemistry 49 (44), 9488-9497, 2010 | 164 | 2010 |
| The transient receptor potential melastatin 2 (TRPM2) channel contributes to β-amyloid oligomer-related neurotoxicity and memory impairment VG Ostapchenko, M Chen, MS Guzman, YF Xie, N Lavine, J Fan, ... Journal of Neuroscience 35 (45), 15157-15169, 2015 | 156 | 2015 |
| Highly efficient protein misfolding cyclic amplification N Gonzalez-Montalban, N Makarava, VG Ostapchenko, R Savtchenk, ... PLoS Pathogens 7 (2), e1001277, 2011 | 122 | 2011 |
| Expression, purification, and characterization of human enteropeptidase catalytic subunit in Escherichia coli ME Gasparian, VG Ostapchenko, AA Schulga, DA Dolgikh, ... Protein expression and Purification 31 (1), 133-139, 2003 | 120 | 2003 |
| The prion protein ligand, stress-inducible phosphoprotein 1, regulates amyloid-β oligomer toxicity VG Ostapchenko, FH Beraldo, AH Mohammad, YF Xie, PHF Hirata, ... Journal of Neuroscience 33 (42), 16552-16564, 2013 | 99 | 2013 |
| A new mechanism for transmissible prion diseases N Makarava, GG Kovacs, R Savtchenko, I Alexeeva, VG Ostapchenko, ... Journal of Neuroscience 32 (21), 7345-7355, 2012 | 79 | 2012 |
| Conformational switching within individual amyloid fibrils N Makarava, VG Ostapchenko, R Savtchenko, IV Baskakov Journal of Biological Chemistry 284 (21), 14386-14395, 2009 | 78 | 2009 |
| Two amyloid states of the prion protein display significantly different folding patterns VG Ostapchenko, MR Sawaya, N Makarava, R Savtchenko, KPR Nilsson, ... Journal of molecular biology 400 (4), 908-921, 2010 | 73 | 2010 |
| Regulation of amyloid β oligomer binding to neurons and neurotoxicity by the prion protein-mGluR5 complex FH Beraldo, VG Ostapchenko, FA Caetano, ALS Guimaraes, GDS Ferretti, ... Journal of Biological Chemistry 291 (42), 21945-21955, 2016 | 66 | 2016 |
| Molecular structure of amyloid fibrils controls the relationship between fibrillar size and toxicity YJ Lee, R Savtchenko, VG Ostapchenko, N Makarava, IV Baskakov PloS one 6 (5), e20244, 2011 | 51 | 2011 |
| The polybasic N-terminal region of the prion protein controls the physical properties of both the cellular and fibrillar forms of PrP VG Ostapchenko, N Makarava, R Savtchenko, IV Baskakov Journal of molecular biology 383 (5), 1210-1224, 2008 | 49 | 2008 |
| Chronic hM3Dq signaling in microglia ameliorates neuroinflammation in male mice W Binning, AE Hogan-Cann, DY Sakae, M Maksoud, V Ostapchenko, ... Brain, Behavior, and Immunity 88, 791-801, 2020 | 44 | 2020 |
| Biochemical characterization of human enteropeptidase light chain ME Gasparian, VG Ostapchenko, DA Dolgikh, MP Kirpichnikov Biochemistry (Moscow) 71, 113-119, 2006 | 44 | 2006 |
| Increased prion protein processing and expression of metabotropic glutamate receptor 1 in a mouse model of Alzheimer's disease VG Ostapchenko, FH Beraldo, ALS Guimarães, S Mishra, M Guzman, ... Journal of neurochemistry 127 (3), 415-425, 2013 | 42 | 2013 |
| Laminin‐γ1 chain and stress inducible protein 1 synergistically mediate PrPC‐dependent axonal growth via Ca2+ mobilization in dorsal root ganglia neurons TG Santos, FH Beraldo, GNM Hajj, MH Lopes, M Roffe, FCS Lupinacci, ... Journal of neurochemistry 124 (2), 210-223, 2013 | 39 | 2013 |
| Highly promiscuous nature of prion polymerization N Makarava, CI Lee, VG Ostapchenko, IV Baskakov Journal of Biological Chemistry 282 (50), 36704-36713, 2007 | 35 | 2007 |
| Domains of STIP1 responsible for regulating PrPC-dependent amyloid-β oligomer toxicity A Maciejewski, VG Ostapchenko, FH Beraldo, VF Prado, MAM Prado, ... Biochemical Journal 473 (14), 2119-2130, 2016 | 34 | 2016 |
| Cholinergic regulation of hnRNPA2/B1 translation by M1 muscarinic receptors B Kolisnyk, MA Al-Onaizi, J Xu, GM Parfitt, VG Ostapchenko, G Hanin, ... Journal of Neuroscience 36 (23), 6287-6296, 2016 | 34 | 2016 |
| Regulation of stress-inducible phosphoprotein 1 nuclear retention by protein inhibitor of activated STAT PIAS1 IN Soares, FA Caetano, J Pinder, BR Rodrigues, FH Beraldo, ... Molecular & Cellular Proteomics 12 (11), 3253-3270, 2013 | 32 | 2013 |
Vania PradoProfessor, University of Western OntarioVerified email at uwo.ca