Directed evolution of genetic parts and circuits by compartmentalized partnered replication JW Ellefson, AJ Meyer, RA Hughes, JR Cannon, JS Brodbelt, ... Nature biotechnology 32 (1), 97-101, 2014 | 191 | 2014 |
Directed Evolution of a Panel of Orthogonal T7 RNA Polymerase Variants for in Vivo or in Vitro Synthetic Circuitry AJ Meyer, JW Ellefson, AD Ellington ACS synthetic biology 4 (10), 1070-1076, 2015 | 156 | 2015 |
Synthetic evolutionary origin of a proofreading reverse transcriptase JW Ellefson, J Gollihar, R Shroff, H Shivram, VR Iyer, AD Ellington Science 352 (6293), 1590-1593, 2016 | 147 | 2016 |
Directed evolution of a synthetic phylogeny of programmable Trp repressors JW Ellefson, MP Ledbetter, AD Ellington Nature chemical biology 14 (4), 361-367, 2018 | 70 | 2018 |
Addicting diverse bacteria to a noncanonical amino acid DS Tack, JW Ellefson, R Thyer, B Wang, J Gollihar, MT Forster, ... Nature Chemical Biology 12 (3), 138-140, 2016 | 67 | 2016 |
Bacteriophages use an expanded genetic code on evolutionary paths to higher fitness MJ Hammerling, JW Ellefson, DR Boutz, EM Marcotte, AD Ellington, ... Nature chemical biology 10 (3), 178-180, 2014 | 61 | 2014 |
Abiotic self-replication AJ Meyer, JW Ellefson, AD Ellington Accounts of Chemical Research 45 (12), 2097-2105, 2012 | 44 | 2012 |
Identification of tumor-reactive B cells and systemic IgG in breast cancer based on clonal frequency in the sentinel lymph node JR McDaniel, SC Pero, WN Voss, GS Shukla, Y Sun, S Schaetzle, CH Lee, ... Cancer Immunology, Immunotherapy 67, 729-738, 2018 | 38 | 2018 |
Library generation by gene shuffling AJ Meyer, JW Ellefson, AD Ellington Current protocols in molecular biology 105 (1), 15.12. 1-15.12. 7, 2014 | 38 | 2014 |
Cellular reagents for diagnostics and synthetic biology S Bhadra, A Pothukuchy, R Shroff, AW Cole, M Byrom, JW Ellefson, ... PLoS One 13 (8), e0201681, 2018 | 31 | 2018 |
A facile technology for the high-throughput sequencing of the paired VH: VL and TCRβ: TCRα repertoires H Tanno, JR McDaniel, CA Stevens, WN Voss, J Li, R Durrett, J Lee, ... Science Advances 6 (17), eaay9093, 2020 | 29 | 2020 |
Compartmentalized partnered replication for the directed evolution of genetic parts and circuits Z Abil, JW Ellefson, JD Gollihar, E Watkins, AD Ellington Nature protocols 12 (12), 2493-2512, 2017 | 27 | 2017 |
An in vitro Autogene EA Davidson, AJ Meyer, JW Ellefson, M Levy, AD Ellington ACS synthetic biology 1 (5), 190-196, 2012 | 24 | 2012 |
In Vitro Selection for Small-Molecule-Triggered Strand Displacement and Riboswitch Activity L Martini, AJ Meyer, JW Ellefson, JN Milligan, M Forlin, AD Ellington, ... ACS Synthetic Biology 4 (10), 1144-1150, 2015 | 23 | 2015 |
New letters for life's alphabet R Thyer, J Ellefson Nature 509 (7500), 291-292, 2014 | 21 | 2014 |
Recovery of Information Stored in Modified DNA with an Evolved Polymerase R Shroff, JW Ellefson, SS Wang, AA Boulgakov, RA Hughes, AD Ellington ACS Synthetic Biology 11 (2), 554-561, 2022 | 8 | 2022 |
High-throughput discovery of antitumor antibodies mined from sentinel lymph node B cells and circulating IgG of breast cancer patients JR McDaniel, SC Pero, WN Voss, GS Shukla, Y Sun, S Schaetzle, CH Lee, ... Cancer immunology, immunotherapy: CII 67 (5), 729, 2018 | 2 | 2018 |
Thermostable reverse transcriptase A Ellington, J Ellefson, J Gollihar US Patent 11,912,991, 2024 | 1 | 2024 |
Methods and kits for using recombinant microorganisms as direct reagents in biological applications A Ellington, S Bhadra, J Ellefson, J Gollihar, A Pothukuchy, M Byrom, ... US Patent 11,807,901, 2023 | 1 | 2023 |
Thermostable reverse transcriptase A Ellington, J Ellefson, J Gollihar US Patent 10,858,652, 2020 | 1 | 2020 |