Biological, clinical and population relevance of 95 loci for blood lipids TM Teslovich, K Musunuru, AV Smith, AC Edmondson, IM Stylianou, ... Nature 466 (7307), 707-713, 2010 | 4171 | 2010 |
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study BF Voight, GM Peloso, M Orho-Melander, R Frikke-Schmidt, M Barbalic, ... The Lancet 380 (9841), 572-580, 2012 | 2677 | 2012 |
Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study R Heinzer, S Vat, P Marques-Vidal, H Marti-Soler, D Andries, N Tobback, ... The Lancet Respiratory Medicine 3 (4), 310-318, 2015 | 2657 | 2015 |
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ... Nature genetics 42 (2), 105-116, 2010 | 2611 | 2010 |
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk CKDGen Consortium, KidneyGen Consortium, EchoGen consortium, ... Nature 478 (7367), 103-109, 2011 | 2362 | 2011 |
Hundreds of variants clustered in genomic loci and biological pathways affect human height H Lango Allen, K Estrada, G Lettre, SI Berndt, MN Weedon, F Rivadeneira, ... Nature 467 (7317), 832-838, 2010 | 2351 | 2010 |
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease H Schunkert, IR König, S Kathiresan, MP Reilly, TL Assimes, H Holm, ... Nature genetics 43 (4), 333-338, 2011 | 2275 | 2011 |
Common variants near MC4R are associated with fat mass, weight and risk of obesity RJF Loos, CM Lindgren, S Li, E Wheeler, JH Zhao, I Prokopenko, ... Nature genetics 40 (6), 768-775, 2008 | 1604 | 2008 |
Genome-wide association study identifies eight loci associated with blood pressure C Newton-Cheh, T Johnson, V Gateva, MD Tobin, M Bochud, L Coin, ... Nature genetics 41 (6), 666-676, 2009 | 1451 | 2009 |
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants Heart Attack Risk in Puget Sound. Schwartz Stephen M 20 26 Siscovick David S ... Nature genetics 41 (3), 334-341, 2009 | 1317 | 2009 |
Genome-wide association analysis identifies 20 loci that influence adult height MN Weedon, H Lango, CM Lindgren, C Wallace, DM Evans, M Mangino, ... Nature genetics 40 (5), 575-583, 2008 | 1012 | 2008 |
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance AK Manning, MF Hivert, RA Scott, JL Grimsby, N Bouatia-Naji, H Chen, ... Nature genetics 44 (6), 659-669, 2012 | 936 | 2012 |
Variants in MTNR1B influence fasting glucose levels I Prokopenko, C Langenberg, JC Florez, R Saxena, N Soranzo, ... Nature genetics 41 (1), 77-81, 2009 | 931 | 2009 |
An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28 DR Owen, AJ Yeo, RN Gunn, K Song, G Wadsworth, A Lewis, C Rhodes, ... Journal of Cerebral Blood Flow & Metabolism 32 (1), 1-5, 2012 | 826 | 2012 |
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people MR Nelson, D Wegmann, MG Ehm, D Kessner, P St. Jean, C Verzilli, ... Science 337 (6090), 100-104, 2012 | 821 | 2012 |
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations M Kolz, T Johnson, S Sanna, A Teumer, V Vitart, M Perola, M Mangino, ... PLoS genetics 5 (6), e1000504, 2009 | 788 | 2009 |
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture SI Berndt, S Gustafsson, R Mägi, A Ganna, E Wheeler, MF Feitosa, ... Nature genetics 45 (5), 501-512, 2013 | 786 | 2013 |
The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome M Firmann, V Mayor, PM Vidal, M Bochud, A Pécoud, D Hayoz, ... BMC cardiovascular disorders 8, 1-11, 2008 | 782 | 2008 |
Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease P Elliott, JC Chambers, W Zhang, R Clarke, JC Hopewell, JF Peden, ... Jama 302 (1), 37-48, 2009 | 756 | 2009 |
Atherogenic dyslipidemia in HIV-infected individuals treated with protease inhibitors D Périard, A Telenti, P Sudre, JJ Cheseaux, P Halfon, MJ Reymond, ... Circulation 100 (7), 700-705, 1999 | 756 | 1999 |