Antimalarial activity of potential inhibitors of Plasmodium falciparum lactate dehydrogenase enzyme selected by docking studies J Penna-Coutinho, WA Cortopassi, AA Oliveira, TCC França, AU Krettli PloS one 6 (7), e21237, 2011 | 176 | 2011 |
Selective inhibitors for JNK signalling: a potential targeted therapy in cancer Q Wu, W Wu, V Jacevic, TCC Franca, X Wang, K Kuca Journal of enzyme inhibition and medicinal chemistry 35 (1), 574-583, 2020 | 170 | 2020 |
Malária: aspectos históricos e quimioterapia TCC França, MG Santos, JD Figueroa-Villar Química Nova 31, 1271-1278, 2008 | 152 | 2008 |
O uso do canabidiol no tratamento da epilepsia RLA MATOS, LA Spinola, LL Barboza, DR Garcia, TCC França, ... Revista Virtual de Química 9 (2), 786-814, 2017 | 133 | 2017 |
Novichoks: the dangerous fourth generation of chemical weapons TCC Franca, DAS Kitagawa, SFA Cavalcante, JAV da Silva, ... International journal of molecular sciences 20 (5), 1222, 2019 | 123 | 2019 |
Aspectos químicos e biológicos do óleo essencial de cravo da índia RS Affonso, MN Rennó, GBCA Slana, TCC Franca Revista Virtual de Química 4 (2), 146-161, 2012 | 120 | 2012 |
New approaches in antimalarial drug discovery and development: a review ACC Aguiar, EMM da Rocha, NB de Souza, TCC França, AU Krettli Memorias do Instituto Oswaldo Cruz 107, 831-845, 2012 | 105 | 2012 |
Synthesis and biological activity of hydrazones and derivatives: A review J de Oliveira Carneiro Brum, TCC França, SR LaPlante, JDF Villar Mini reviews in medicinal chemistry 20 (5), 342-368, 2020 | 97 | 2020 |
New insights on molecular interactions of organophosphorus pesticides with esterases I Mangas, J Estevez, E Vilanova, TCC França Toxicology 376, 30-43, 2017 | 80 | 2017 |
Homology modeling: an important tool for the drug discovery TCC França Journal of Biomolecular Structure and Dynamics 33 (8), 1780-1793, 2015 | 75 | 2015 |
A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase K Kuca, K Musilek, D Jun, J Zdarova-Karasova, E Nepovimova, O Soukup, ... BMC Pharmacology and Toxicology 19, 1-10, 2018 | 69 | 2018 |
Reactivation steps by 2-PAM of tabun-inhibited human acetylcholinesterase: reducing the computational cost in hybrid QM/MM methods A da Silva Gonçalves, TCC França, MS Caetano, TC Ramalho Journal of biomolecular structure and dynamics 32 (2), 301-307, 2014 | 69 | 2014 |
Antimalarial activity and mechanisms of action of two novel 4-aminoquinolines against chloroquine-resistant parasites ACC Aguiar, RM Santos, FJB Figueiredo, WA Cortopassi, AS Pimentel, ... PLoS One 7 (5), e37259, 2012 | 69 | 2012 |
Neurotoxic effects associated with current uses of organophosphorus compounds I Mangas, E Vilanova, J Estévez, TCC França Journal of the Brazilian Chemical Society 27 (5), 809-825, 2016 | 61 | 2016 |
Molecular dynamics simulations and QM/MM studies of the reactivation by 2-PAM of tabun inhibited human acethylcolinesterase AS Gonçalves, TCC França, JD Figueroa-Villar, PG Pascutti Journal of the Brazilian Chemical Society 22, 155-165, 2011 | 60 | 2011 |
Current approaches against Alzheimer's disease in clinical trials K Kuca, O Soukup, P Maresova, J Korabecny, E Nepovimova, B Klimova, ... Journal of the Brazilian Chemical Society 27 (4), 641-649, 2016 | 58 | 2016 |
Computational enzymology and organophosphorus degrading enzymes: promising approaches toward remediation technologies of warfare agents and pesticides T C. Ramalho, A A. de Castro, D R. Silva, M Cristina Silva, T CC Franca, ... Current Medicinal Chemistry 23 (10), 1041-1061, 2016 | 58 | 2016 |
A three-dimensional structure of Plasmodium falciparum serine hydroxymethyltransferase in complex with glycine and 5-formyl-tetrahydrofolate. Homology modeling and molecular … TCC França, PG Pascutti, TC Ramalho Biophysical chemistry 115 (1), 1-10, 2005 | 51 | 2005 |
Molecular modeling and in vitro reactivation study between the oxime BI-6 and acetylcholinesterase inhibited by different nerve agents JOS Giacoppo, T CC França, K Kuča, EFF Cunha, R Abagyan, ... Journal of biomolecular structure and dynamics 33 (9), 2048-2058, 2015 | 50 | 2015 |
Molecular dynamics of the interaction of pralidoxime and deazapralidoxime with acetylcholinesterase inhibited by the neurotoxic agent tabun AS Gonçalves, TCC França, A Wilter, JD Figueroa-Villar Journal of the Brazilian Chemical Society 17, 968-975, 2006 | 47 | 2006 |